Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5 (HP-β-CD) Pharmaceutical Excipients
Ruifu Chemical ndiyo inotungamira kugadzira Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) nehupamhi hwepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, sevhisi yakanakisa, idiki uye yakawanda huwandu huripo.Tenga Hydroxypropyl-β-Cyclodextrin,Please contact: alvin@ruifuchem.com
| Chemical Name | Hydroxypropyl-β-Cyclodextrin |
| Mashoko anoreva zvakafanana | Cyclodextrin HPB;Hydroxypropyl-Beta-Cyclodextrin;(2-Hydroxypropyl) -β-Cyclodextrin;(2-Hydroxypropyl) -beta-Cyclodextrin;beta-Hydroxypropylcyclodextrin;HBC;HPBCD;HP-β-CD |
| Stock Status | MuStock, Commercial Production |
| Nhamba yeCAS | 128446-35-5 |
| Molecular Formula | C63H112O42 |
| Molecular Weight | 1541.54 g/mol |
| Melting Point | 262.0~269.0℃ |
| Density | 1.05 |
| Kutenderera kwakananga [a]20/D | +120° kusvika +135° (C=1, H2O) |
| Mvura Solubility | Soluble mumvura |
| COA & MSDS | Available |
| Yemahara Muenzaniso | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Zvinotsanangurwa | Results |
| Chitarisiko | White Powder, Insipid, Innocent | Conforms |
| IR Spectrum | Same Absorption Mabhendi ane USP Hydroxypropyl Betadex RS | Conforms |
| pH | 5.0~7.5 | 6.57 |
| Kujeka Kwemhinduro | Yakajeka uye isina Ruvara Solution | Conforms |
| Kurasika paKuomesa | ≤10.0% | 3.5% |
| Residue paIgnition | ≤0.20% | 0.09% |
| Heavy Metals | ≤20ppm | <10ppm |
| Chloride | ≤0.05% | <0.05% |
| Molar Kutsiva | 0.4~1.5 | 0.63 |
| Conductivity | 10% (w / v) Mvura Solution ≤200μS / cm | 154µS/cm |
| Dhigirii reKutsiva | 2.8~10.5 | 5.3 |
| Residue Betadex | ≤1.50% | 0.12% |
| Propylene Glycol | ≤2.50% | 0.29% |
| Propylene oxide | ≤1ppm | <1ppm |
| Chero Kumwe Kusachena Kumwechete | ≤0.25% | <0.25% |
| Huwandu Hwezvimwe Zvisina Kuchena | ≤1.00% (Kunze Betadex uye Propylen Glycol) | 0.51% |
| TAMC | ≤1000cfu/g | 30cfu/g |
| TYMC | ≤100cfu/g | 10cfu/g |
| Escherichia Coli | Not Detectable | Conforms |
| Salmonella | Absent | Absent |
| Bacterial Endotoxins | <10IU/g | <10IU/g |
| Mhedziso | Yakaedzwa uye Inopindirana neiyo Standard USP35 | |
Package:Fluorinated Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mudziyo wakavharwa zvakasimba uye chengeta muimba inotonhorera, yakaoma uye ine mhepo yakanaka kure nezvinhu zvisingaenderani.Dzivirira kubva kuchiedza uye unyoro.Hazvienderani neakasimba oxidizing agents.
KutumiraKuendesa kupasirese nemhepo, neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
| Tsanangudzo Yekuchengetedza | 24/25 - Dzivisa kusangana neganda nemeso. |
| WGK Germany | 3 |
| RTECS | GU2293332 |
| HS Code | 3505100000 |
Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) inoshandiswa zvakanyanya kugadziriswa cyclodextrin, iyo lipophilic cavity inoumbwa ne7 glucose units.Kunyungudika kwezvinodhaka mumvura kunosimudzirwa zvakanyanya nekugadzirisa neHP-β-CD.Enteric coating, yakagadziriswa kuburitswa maumbirwo, buccal uye transdermal drug delivery.
Hydroxypropyl-β-Cyclodextrin, hydroxyalkyl derivative, inowana kushandiswa semotokari yekugadzira iyo inoshandiswa kusimbisa kunyungudika kwemishonga mumagetsi ekugadzirisa kwekubudirira kwemishonga yemishonga kune biological systems.Inowanzo shandiswa sechinotsiva α-, β- uye γ-Cyclodextrins.
Hydroxypropyl betadex yakaongororwa zvakanyanya mumishonga uye yakanyanya kushandiswa sesolubilizer yehydrophobic mamorekuru mune zvinwiwa zvemukanwa, oral solids, parenterals, yakamanikidzwa metered dose inhalers, yakaoma poda inhalers, uye topical formulations.Yakave yakaratidzawo kuita seyakagadzikana panguva yekugadzirisa nekuchengetedza maitiro.Hydroxypropyl betadex inclusion complexes anonzi anoratidza michina zvimiro zvakasiyana kubva kune zvakachena zvinhu.Iyo yakashumwa mukana wehydroxypropyl betadex pane isina kuisirwa b-cyclodextrin ndiko kunyungudika kwayo kukuru kwemvura.
1. Solubilization uye solubilization, ita kuti mishonga isingagadziriswi inyunguduke, inovandudza kunyungudika kwezvikamu zvinoshanda zvemishonga ine mafuta, chinangwa chekuendesa zvinodhaka uye kudzivirira kushanda kwemishonga yemishonga.
2. Kuvandudza bioavailability yemushonga, wedzera kurapa kwemushonga kana kuderedza dosi.
3. Gadzirisa kana kudzora kusunungurwa kwezvinodhaka kuderedza migumisiro yechirwere.
4. Fukidza kunhuwa kwakashata.
1) Mumunda wemishonga,
1. Hydroxypropyl Beta Cyclodextrin inogona kuwedzera kunyungudika kwemushonga uye kuwanikwa kwebiological, kuwedzerawo maitiro akanaka uye kuderedza muyero.
2. HP-β-CD inogona kudzora kana kugadzirisa reactive speed, kuderedza chepfu yezvinodhaka uye kuwedzera kugadzikana kwezvinodhaka.
3. Yakanaka jekiseni solubilizer uye zvinodhaka excipients nokuda kwepasi pamusoro pekuita uye hemolytic basa, hapana tsandanyama kushatirwa.
4. HP-β-CD haisi kungoshandiswa mumishonga yemuromo, jekiseni, mucosal drug delivery system, transdermal drug delivery system, lipotropy inotarisa mishonga inotakura, asiwo inogona kushandiswa seprotein protective agent uye stabilizer.
5. Kuvandudza organoleptic maitiro ezvinovava kana zvisingafadzi zvinoshanda.
2) Mumunda wekudya,
1. HP-β-CD inogona kudzivirira kubuda kwezvinhu zvinoputika kuchengetedza kugadzikana kwezvokudya zvayo, kubvisa kunhuhwirira kunotyisa uye kunogona kuwedzera zvakanyanya migumisiro ye emulsification pamwe chete nekushandiswa kwekudya emulsifiers.
2. HP-β-CD inogonawo kuita kuchengetedza kusunungurwa kwezvokudya zvishoma nezvishoma, kusimudza maitiro e-anti-corrosion uye kuwedzera hupenyu hwesherufu yezvokudya.
3) In Cosmetics Indasitiri
1. Muzvizoro zvinhu mbishi inoshandiswa se stabilizer, emulsifier, solubilizer nezvimwe.
2. HP-β-CD inogona kuderedza kukurudzira kuganda, uye kuwedzera kugadzikana kwezvinhu zvinoshanda.
3. HP-β-CD inogona kuderedza kana kuvhara kunhuhwirira kwakashata kwezvokudya zvinovaka muviri.
4. Kudzivirira kuumbwa kwehutano hwehutu, oxidation, kuwedzera infusibility, essence, perfume mvura-soluble uye Chengetedza kunhuhwirira kunononoka kusunungurwa uye kusingaperi.
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