Dantrolene Sodium Salt Hydrate CAS 14663-23-1 API Factory Yepamusoro Hunhu
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Zita reKemikari: Dantrolene Sodium Salt Hydrate
CAS: 14663-23-1
Skeletal Muscle Relaxant.Calcium Channel Inhibitor
API High Quality, Commercial Production
Chemical Name | Dantrolene Sodium Munyu Hydrate |
Mashoko anoreva zvakafanana | 1-[5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium Munyu Hydrate |
Nhamba yeCAS | 14663-23-1 |
Nhamba yeCAT | RF-API78 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
Molecular Formula | C14H11N4NaO5 |
Molecular Weight | 338.25 |
Solubility | Soluble muDMSO |
Shipping Condition | Yakatumirwa Pasi peAmbient Temperature |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Yero-Orenji kusvika kuOrange Crystalline Powder.Hapana humbowo hunoonekwa hwekusvibiswa nezvinhu zvekunze |
Identification A | Iyo IR Absorption (197K) |
Kuzivikanwa B | Iyo nguva yekuchengetedza yepamusoro peak muchromatogram yeassay kugadzirira inoenderana neiyo muchromatogram yeyakajairwa gadziriro, sezvakawanikwa muyedzo. |
Chiziviso C | Inosangana nezvinodiwa zvekuyedzwa kwemoto weSodium (191) |
Kuzivikanwa D | Chikamu 1: Iyo yakawanda, chena, crystalline precipitate inoumbwa Chikamu 2: Mvura haina kupera Chikamu 3: Mvura inonyungudika zvachose Chikamu 4: Hapana mvura inogadzirwa |
Mvura Yemukati (neKF) | 14.5%~17.0% |
Particle Size | 90% isingasviki 200um |
Assay | 90.0% ~ 96.0% yeC14H10N405 pane anhydrous basis |
Related Substances | (HPLC, Nzvimbo%) |
Related Compound A | ≤0.15% |
Inoenderana Musanganiswa B | ≤0.50% |
Inoenderana Musanganiswa C | ≤0.30% |
Residual Solvents | |
Ethanol | ≤2000ppm |
Methanol | ≤2000ppm |
Acetone | ≤2000ppm |
DMF | ≤620ppm |
Heavy Metals | ≤10ppm |
Sherufu Hupenyu | 2 Makore |
Test Standard | United States Pharmacopoeia (USP) |
Usage | Skeletal Muscle Relaxant.Calcium Channel Inhibitor |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
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Dantrolene Sodium Salt Hydrate (CAS 14663-23-1), idiki molecule inhibitor yeRyonodine receptor antagonist uye Calcium chiteshi inhibitor.Dantrolene Sodium Munyu is skeletal muscle relaxant, iyo inodzivisa intracellular Ca 2 + kusunungurwa kubva kune sarcoplasmic reticulum.Kuvharwa kweCa2 + kuburitswa kubva ku sarcoendoplasmic reticulum, ine hukama zvakanyanya nekunakidzwa uye kudhonzwa kwemhasuru, inoburitsa tsandanyama inozorodza mhedzisiro yakabatana neDantrolene.Iyo neurotoxicity inoratidzwa neyakanzi glutamate chiitiko inoenderana nekukwira kwakanyanya mu cytoplasmic Ca2 + mazinga, uye Dantrolene inoenderana inoratidzwa seyeuroprotective agent kurwisa neurotrasmitter-induced excitotoxicity.Dantrolene, Sodium Munyu inhibitor yeRyR-1 uye RyR-3.