Daptomycin CAS 103060-53-3 Kuchena ≥95.0% API Factory High Purity

Tsanangudzo Pfupi

Kemikari Zita: Daptomycin

CAS: 103060-53-3

Chitarisiko: Yellow kana Pale Yellow Powder

Kuchena: ≥95.0% (Yakaverengerwa pane yakaomeswa hwaro)

Daptomycin mukurapa kweimwe ganda rakaomarara uye nyoro hutachiona hutachiona hunokonzerwa ne gram-positive bacteria.

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

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Product Detail

Product Tags

Tsanangudzo:

Mugadziri ane Kuchena Kwepamusoro uye Hwakagadzikana Hunhu
Kemikari Zita: Daptomycin
CAS: 103060-53-3
API High Quality, Commercial Production

Chemical Properties:

Chemical Name	Daptomycin
Mashoko anoreva zvakafanana	LY146032
Nhamba yeCAS	103060-53-3
Nhamba yeCAT	RF-API10
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C72H101N17O26
Molecular Weight	1620.69
Melting Point	202.0~204.0℃
Solubility	Solube muMethanol
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Yellow or Pale Yellow Powder
Kuzivikanwa HPLC	Nguva yekuchengeta yenhongonya huru yemuenzaniso mhinduro inofanirwa kuenderana neiyo yereferensi mwero.
Kuzivikanwa IR	IR spectrum yemuyedzo sampuli inofanirwa kuenderana neIR spectrum yereferensi standard.
Kuonekwa kweSolution	Kujeka Mushonga unofanirwa kuve wakajeka kana kusanyanya kutaurwa kupfuura iyo yereferensi kumiswa II.
Specific Optical Rotation	+17.0 ° kusvika +25.0 °
pH	4.0 kusvika 5.0
Residue paIgnition	≤1.0%
Anhydro-Daptomycin	≤2.5%
β-Isomer	≤0.50%
Hydrolysis Kusachena	≤0.50%
Kusachena 1	≤0.75%
Kusachena 2	≤0.75%
Kusachena 3	≤0.75%
Chero Kumwe Kusachena	≤0.15%
Zvose Zvisina Kuchena	≤5.0%
Heavy Metals	≤30ppm
Mvura	≤5.0%
Kuchena	≥95.0% (Yakaverengerwa pane yakaomeswa hwaro)
Bacterial Endotoxins	<0.3EU/mg
Residual Solvents n-Butanol	≤5000ppm
ResidualSolvents Isopropanol	≤5000ppm
Residual Solvents Ethanol	≤5000ppm
Iyo Microbial Limit TAMC	≤100cfu/g
Microbial Limit TYMC	≤10cfu/g
E.Coil	Haina Kuonekwa
Test Standard	Enterprise Standard
Storage Conditions	Chengetedza mumidziyo yakasimba, uye chengetedza pa -25 ~ -10 ℃.
Usage	Active Pharmaceutical Ingredient (API)

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.

Zvakanakira:

FAQ:

Application:

Daptomycin (CAS: 103060-53-3) imhando yecyclic lipopeptide antibiotics ine novel structure.Inotorwa kubva kuStreptomyces fermentation broth.Yakawanikwa naEli Lilly Company muma1980, uye yakabudirira kugadzirwa muna 1997 neCubist Pharmaceuticals.Haisi kungova neinoveli chemakemikari chimiro asiwo ine maitiro ekuita ayo akasiyana nechero mushonga unorwisa mabhakitiriya wakambobvumidzwa kare: inodzivirira sero nekukanganisa kutakurwa kwemaamino acids kuburikidza nesero membrane, nekudaro ichivharira sero rusvingo peptidoglycan biosynthesis uye nekushandura chimiro cheiyo. cell membrane.Inogona kuparadza bhakitiriya cell membrane basa mune zvakawanda zvinhu, uye nekukurumidza kuuraya giremu-positive mabhakitiriya.Pamusoro pebasa rekutora mabhakitiriya akawanda ane giremu ane giremu, zvinotonyanya kukosha ndezvokuti Daptomycin ine simba rakasimba mukurapa majekiseni ari oga ayo akaratidza zviratidzo zvekuramba methicillin, vancomycin uye linezolid.Iyi pfuma yakakosha kuchipatara kune varwere vanotambura nehutachiona hwakanyanya.MunaGunyana 2003, US Food and Drug Administration yakanga yabvumidza kekutanga kuti Daptomycin (CAS: 103060-53-3) ishandiswe pakurapa utachiona hwakanyanya hweganda.Muna Kurume 2006, yakabvumidzwa kurapa zvirwere zvinotapukira.Muna Ndira 2006, inotenderwa neEuropean Commission kurapwa kwezvimwe zvakaomarara zveganda uye zvinyoro-nyoro zvipembenene zvinokonzerwa ne gram-positive bacteria.Musi waGunyana 6, 2007, Cubist Pharmaceuticals yakazivisa kuti European Union yakabvumidza mushonga wayo unorwisa mabhakitiriya, Cubicin kurapwa kwemoyo wekurudyi endocarditis inokonzerwa nehutachiona hweStaphylococcus aureus uye yakaoma ganda uye zvinyoro zvinyoro zvirwere zvine chekuita nezvirwere zvinokonzerwa neStaphylococcus aureus.