Darunavir CAS 206361-99-1 Anti-HIV Purity ≥99.0% API High Purity HIV Protease Inhibitor
Manufacturer SupplyDarunavir Related Products:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Chemical Name | Darunavir |
| Mashoko anoreva zvakafanana | TMC114;UIC-94017 |
| Nhamba yeCAS | 206361-99-1 |
| Nhamba yeCAT | RF-API68 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
| Molecular Formula | C27H37N3O7S |
| Molecular Weight | 547.66 |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kana Isina-White Crystalline Powder |
| Identification | MS/HNMR HPLC |
| Solubility | Soluble muDMSO, Zvishoma Soluble mumvura |
| Melting Point | 74.0 ~ 76.0℃ |
| Identification | 1H NMR |
| Kuchena / Analysis Method | ≥99.0% (HPLC) |
| Related Substances | |
| Max Single Kusachena | ≤0.30% |
| Zvose Zvisina Kuchena | ≤1.0% |
| Residual Solvents | Ethanol ≤0.30% |
| Kurasika paKuomesa | ≤0.50% |
| Residue paIgnition | ≤0.10% |
| Heavy Metals | ≤20ppm |
| Arsenic | ≤1.5ppm |
| Test Standard | Enterprise Standard |
| Usage | Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor Anti-HIV |
Package: Bhodhoro, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Darunavir (zita rechiratidzo Prezista, yaimbozivikanwa seTMC114) mushonga weprotease inhibitor unoshandiswa kurapa utachiona hweHIV.Darunavir inzira yeOARAC inokurudzirwa kurapwa kune vanhu vakuru nevachiri kuyaruka vane ruzivo rwekurapa.Darunavir rudzi rutsva rwe non peptide anti retroviral protease inhibitors mukurapa kweAIDS.Yakatanga kugadzirwa nebazi reJohnson pharmaceutical Iceland, Tibotec.Ndeyepamusoro-soro yebioavailability muzvikamu zvitanhatu zveprotease inhibitors (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir uye ABT378/r).Inoshanda nekuvharira kuumbwa kwehutachiona hutsva uye hwakura kubva pamusoro pemasero ane hutachiona uye nekuvharira protease yehutachiona.Kana chigadzirwa chacho chikashandiswa kwenguva yakareba, kazhinji chinogona kuderedza hutachiona hweHIV muropa, kuwedzera nhamba yeCD4 masero, kuderedza mukana wekutapukirwa kweHIV, kuvandudza hupenyu uye kuwedzera hupenyu.Inokodzera vanhu vakuru vane hutachiwana hweHIV asi isingaite pakushandiswa kwemishonga iripo.Mushonga unofanirwa kusanganiswa nekushandiswa kwemishonga yakaderera yeritonavir kana mamwe maantiretroviral agents, kuitira kuvandudza kushanda.Iyo antiviral chiitiko mu vitro inogona kuongororwa nekuve inopesana neacute uye isingaperi ine hutachiona lymphocytes uye lymphocytes muropa reperipheral.
