Decitabine CAS 2353-33-5 Kuchena > 99.5% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weDecitabine (CAS: 2353-33-5) ine mhando yepamusoro.Isu tinogona kupa COA, kuendesa pasi rese, zvidiki uye huwandu hwakawanda huripo.Kana iwe uchifarira chigadzirwa ichi, ndapota tumira ruzivo rwakadzama runosanganisira nhamba yeCAS, zita rechigadzirwa, huwandu kwatiri.Please contact: alvin@ruifuchem.com
| Chemical Name | Decitabine |
| Mashoko anoreva zvakafanana | 5-Aza-2'-Deoxycytidine;5-Aza-1-(2-Deoxy-β-D-Ribofuranosyl)cytosine;5-Aza-CdR;5-Aza-dC;5-Deoxy-2'-Azacytidine;ZdCyd;DAC;β-Decitabine |
| Nhamba yeCAS | 2353-33-5 |
| Nhamba yeCAT | RF2728 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C8H12N4O4 |
| Molecular Weight | 228.21 |
| Melting Point | 191 ℃ (Zvita.) |
| Sensitive | Mhepo Inonzwa, Inonzwa Kupisa |
| Solubility | Yakanyungudutswa muDMSO;Zvishoma Soluble mumvura |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kana Isina-White Crystalline Powder |
| Identification A | IR: Sample IR Spectrum Inopindirana Neiyo Yeiyo Standard |
| Kuzivikanwa B | HPLC: Iyo RT yeiyo Major Peak yeTest Solution Inoenderana neiyo yeStandard Solution |
| Chiziviso C | PXRD: Zvakanaka |
| Kuchena / Analysis Method | >99.5% (HPLC) |
| Alpha | +56.0°~ 63.0° |
| Kurasika paKuomesa | <0.50% |
| Residue paIgnition | <0.10% |
| Heavy Metals | <20ppm |
| Related Substances | |
| α-Decitabine | <0.20% |
| Single Unknown Kusachena | <0.20% |
| Zvose Zvisina Kuchena | <0.50% |
| Residual Solvents | |
| DMSO | <0.50% |
| Methanol | <0.30% |
| Methyl Formate | <0.05% |
| Acetonitrile | <0.041% |
| Solubility | Zvisina Ruvara Zvakajeka 50 mg/ml, HOAc uye H2O (1:1) Pass |
| Test Standard | Enterprise Standard |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro
Kutenga sei?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Russia, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
Decitabine (CAS: 2353-33-5) (zita rekutengeserana Dacogen), kana 5-Aza-2'-Deoxycytidine.Kemikari, inonzi cytidine analog.Decitabine inonzi hypomethylating agent.Decitabine yakatangwa kurapa myelodysplastic syndromes (MDS).MDS seti yehematologic kusagadzikana inokanganisa mwongo izvo zvinoguma nekusashanda kuumbwa uye kukura kwemasero eropa.Uyezve, varwere vane MDS vane njodzi yakakura yekufambira mberi kune acute myeloid leukemia (AML).Kurapa kwechivanhu kunosanganisira kuwedzerwa ropa, hematopoietic growth factors, uye prophylactic antibiotics, asi matanho aya anongovandudza hupenyu nemigumisiro inopokana pakuchinja kwechirwere.Nepo stem-cell transplantation iri nzira ine hutsinye, inogona kurapa, kuchembera kana zvimwe zvinonetsa zvehutano zvevarwere vazhinji zvinovatadzisa kufunga nezvesarudzo iyi.Kufambira mberi munguva pfupi yapfuura mune yepasi etiology ye MDS, zvisinei, zvakakonzera kugadzirwa kwekirasi nyowani yemakomponi inozivikanwa se '' demethylating agents ''.Decitabine inotevera kuiswa kwakabudirira kwekutanga DNA methyltransferase inhibitor Azacitidine.Iyo hypomethylates DNA nekudzivisa DNA methyltransferase.Inoshanda nenzira yakafanana neAzacitidine, kunyange zvazvo decitabine inogona kuiswa muDNA tambo apo azacitidine inogona kuiswa mumaketani ose eDNA neRNA.Tsvagiridzo reagents: Decitabine inoshandiswa zvakanyanya mumolecular biology, pharmacology, uye kumwe kutsvagisa kwesainzi.Decitabine seyakajeka DNA methyltransferase inhibitor, inodzoreredza DNA methylation process, yakakonzera bundu masero kune akajairwa masero kuti asiyanise kana kuitisa tumor cell apoptosis.Ndokumbira utarise kuti iyo yakakwira yeDecitabine yaizoridza yayo cytotoxic mhedzisiro: inogona kuvharira DNA synthesis inokonzera kufa kwesero.
