Diethylphosphonoacetic Acid CAS 3095-95-2 Kuchena >99.5% (HPLC) Afatinib Dimaleate Intermediate Factory

Tsanangudzo Pfupi:

Kemikari Zita: Diethylphosphonoacetic Acid

CAS: 3095-95-2

Kuchena:> 99.5% (HPLC)

Chitarisiko: Mvura isina Ruvara

Pakati peAfatinib Dimaleate (CAS: 850140-73-7)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Ruifu Chemical Supply Intermediates yeAfatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
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Chemical Properties:

Chemical Name	Diethylphosphonoacetic Acid
Mashoko anoreva zvakafanana	2-(Diethoxyphosphoryl)acetic Acid;(Diethoxyphosphinyl)acetic Acid;Diethyl Carboxymethylphosphonate;NSC 272281
Nhamba yeCAS	3095-95-2
Nhamba yeCAT	RF-PI2024
Stock Status	MuStock, Kukwanisa Kugadzira 30MT/Mwedzi
Molecular Formula	(C2H5O)2P(O)CH2CO2H
Molecular Weight	196.14
Boiling Point	150℃/0.05 mmHg (lit.)
Density	1.220 g/mL pa25℃ (lit.)
Refractive Index	n20/D 1.445 (lit.)
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Colorless Liquid
Kuzivikanwa (HPLC)	Nguva yekuchengetedza yepamusoro peak yakawanikwa kubva kumuenzaniso iri mukati me5% yereferensi sampuli.
Kuchena / Analysis Method	>99.5% (HPLC)
Infrared Spectrum	Inopindirana neChimiro
Proton NMR Spectrum	Inopindirana neChimiro
Kunyorova (KF)	<0.50%
Zvose Zvisina Kuchena	<0.50%
Test Standard	Enterprise Standard
Usage	Pakati peAfatinib Dimaleate (CAS: 850140-73-7)

Package & Kuchengeta:

Package: Fluorinated Bhodhoro, 25kg / Drum, kana zvinoenderana nezvinodiwa nemutengi

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

FAQ:

Application:

Diethylphosphonoacetic Acid (CAS: 3095-95-2), Inoita se nucleophile ye nucleophilic kuwedzera maitiro ekugadzirisa allene epoxides Reactant ye: Stereoselectivity zvidzidzo zveStaudinger reaction;Enantioselective kuumbwa kwe diols kuburikidza ne epoxidation uye hydration reactions;Horner-Wadsworth-Emmons maitiro;Remote chelation inodzorwa Ireland-Claisen rearrangement;Ugi-Dieckmann maitiro ekugadzirwa kwe tetramic acid derivatives;Inoshandiswa kugadzira phosphonoester intermediates kune intramolecular HEW maitiro.Diethylphosphonoacetic Acid iri pakati peAfatinib Dimaleate (CAS: 850140-73-7).Afatinib Dimaleate yakabvumidzwa neUS Food and Drug Administration (FDA) muna 2013 kurapwa kweiyo isiri-diki cell cancer yemapapu (NSCLC).Kunyanya, yakatenderwa kune varwere vanouya ne metastatic NSCLC tumors ine epidermal growth factor receptor (EGFR) exon deletions kana exon 21 mutations.Afatinib Dimaleate inonzi covalent inhibitor yeErbB tyrosine kinases (tyk), iyo inoderedza zviratidzo zveErbB nekusungirirwa kusingadzoreki kweEGFR tyk kusunga nzvimbo.