Doxorubicin Hydrochloride CAS 25316-40-9 API USP Standard Factory High Purity
Mugadziri ane Kuchena Kwepamusoro uye Hwakagadzikana Hunhu
Kemikari Zita: Doxorubicin Hydrochloride
CAS: 25316-40-9
Antitumor Antibiotic Agent.Inhibits DNA Topoisomerase II
API High Quality, Commercial Production
Chemical Name | Doxorubicin Hydrochloride |
Mashoko anoreva zvakafanana | Doxorubicin HCl;Adriamycin HCL;Hydroxydaunorubicin Hydrochloride |
Nhamba yeCAS | 25316-40-9 |
Nhamba yeCAT | RF-API38 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C27H30ClNO11 |
Molecular Weight | 579.98 |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Orange-Red kana Red Crystalline Powder;Hapana humbowo hunoonekwa hwekusvibiswa nezvinhu zvekunze |
Solubility | Soluble mumvura uye methanol;zvishoma soluble mu ethanol;inenge isinganyunguriki muacetone |
Identification A | IR spectrum inoenderana neIR spectrum yereferensi chiyero |
Kuzivikanwa B | Nguva yekuchengetedza yedoxorubicin peak muchromatogram yeAssay kugadzirira inoenderana neiyo muchromatogram yeStandard gadziriro, sezvakawanikwa muAssay. |
pH | 4.0~5.5 |
Mvura Yemukati | ≤4.0% |
Related Substances | |
Kusachena A (Doxorubicinol) | ≤0.50% |
Chero Kumwe Kusachena Kusingazivikanwe | ≤0.20% |
Zvose Zvisingazivikanwe Kusvibiswa | ≤0.50% |
Zvose Zvisina Kuchena | ≤1.0% |
Assay | 98.0% ~ 102.0% yeC27H30ClNO11 yakaverengerwa pane anhydrous, solvent-isina hwaro |
Residual Solvents | |
Acetone | ≤0.50% |
Acetone + Ethanol | ≤2.5% |
Methanol | ≤0.30% |
Dichloromethane | ≤0.06% |
Test Standard | United States Pharmacopeia (USP) Reference Standard |
Usage | Active Pharmaceutical Ingredient (API) |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weDoxorubicin Hydrochloride (CAS: 25316-40-9) ine mhando yepamusoro.Doxorubicin hydrochloride, cytotoxic anthracycline antibiotic, inorwisa cancer chemotherapy agent.Doxorubicin hydrochloride ine simba remunhu DNA topoisomerase I uye topoisomerase II inhibitor ine IC50s ye0.8 μM uye 2.67 μM, zvichiteerana.Doxorubicin hydrochloride induces apoptosis uye autophagy.Doxorubicin inhengo ine simba inorwisa tumour inoshanda kurwisa huwandu hwakawanda hwehutsinye, kusanganisira leukemias, sarcomas, kenza yemazamu, kenza diki yemapapu uye kenza yeovarian.