EDC·HCl CAS 25952-53-8 Coupling Reagent Kuchena > 99.0% (T) Factory

Tsanangudzo Pfupi

1-(3-Dimethylaminopropyl) -3-Ethylcarbodiimide Hydrochloride

Anoreva zvakafanana: EDC·HCl

CAS: 25952-53-8

Kuchena:> 99.0% (Argentmetric Titration)

Kuonekwa: White Crystalline Powder

Coupling Reagent yePeptides Synthesis

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira 1-(3-Dimethylaminopropyl)-3-Ethylcarbodiimide Hydrochloride (EDC · HCl) (CAS: 25952-53-8) nemhando yepamusoro.Ruifu Chemical inopa akateedzana ekudzivirira reagents uye coupling reagents.Ruifu inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, madiki uye akawanda akawanda aripo.Tenga EDC·HCl,Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	1-(3-Dimethylaminopropyl) -3-Ethylcarbodiimide Hydrochloride
Mashoko anoreva zvakafanana	EDC·HCl;EDAC·HCl;EDCI·HCl;EDC Hydrochloride;EDAC Hydrochloride;N-(3-Dimethylaminopropyl)-N′-Ethylcarbodiimide Hydrochloride;1-Ethyl-3-(3-Dimethylaminopropyl)carbodiimide Hydrochloride;N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide Hydrochloride;Mvura Soluble Carbodiimide
Stock Status	MuStock, Mass Production
Nhamba yeCAS	25952-53-8
Molecular Formula	C8H17N3·HCl
Molecular Weight	191.70 g/mol
Melting Point	110.0~115.0℃
Density	0.877 g/mL pa20℃(lit.)
Refractive Index n20/D	1.461
Chengetedza Pasi Inert Gasi	Chengetedza Pasi Inert Gasi
Sensitive	Hygroscopic.Kunyorova, Kupisa Kunzwa
Mvura Solubility	Yakanyatso Soluble mumvura
Solubility	Soluble muDimethylformamide, Doro
Storage Temp.	Nzvimbo Inotonhorera & Yakaoma (<5℃)
COA & MSDS	Available
Category	Coupling Reagents
Brand	Ruifu Chemical

Zvinotsanangurwa:

Items	Kuongorora Maitiro	Results
Chitarisiko	White Crystalline Powder	Zvinoenderana
Melting Point	110.0~115.0℃	112.0~114.0℃
Mvura naKarl Fischer	<0.50%	0.10%
Residue paIgnition	<0.10%	0.04%
Kuchena (Argentmetric Titration)	>99.0%	99.70%
Kuchena / Analysis Method	>99.0% (HPLC)	Zvinoenderana
Infrared Spectrum	Inopindirana neChimiro	Zvinoenderana
Solubility muH2O (100 mg/mL)	Zvisina Ruvara kusvika Zvakanyanya Kufenda Yero, Zvakajeka	Pass
Mhedziso	Chigadzirwa chacho chakaedzwa uye chinoenderana nezvakapihwa

Pakeji/Kuchengeta/Shipping:

Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Hunyoro Inonzwa.Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma (<5℃) yekuchengetera kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.

Test Method:

Properties: Ichi chigadzirwa ichena crystalline poda.
2. Kutsunga zvemukati:
2.1 Zvishandiso uye reagents: potentiometric titrator, nitric acid mhinduro (12.5 wt%), AgNO3 yakajairwa mhinduro (0.1mol/L)
2.2 Kugadzirira uye kushanda kwemuenzaniso:
200 kusvika 220mg yakanyungudutswa mu40ml yemvura yakasvibiswa, uye mushure mokunge 5ml ye nitric acid solution yakawedzerwa, mhinduro yacho yakanyungudutswa nesirivha nitrate.
Mvura yacho yainge yakamisikidzwa kusvika kumagumo.Iyo formula yekuverenga yezvigadzirwa zvemukati ndeyekutevera:
X = (VAgNO3*19.171)/W,
X- The percentage of EDC.HCl, 100%.
V-Iyo vhoriyamu inopedzwa neiyo AgNO3 yakajairwa mhinduro, ml
19.171-1ml AgNO3 yakagadziriswa mhinduro (0.1mol / L) inopedza EDC.HCl mass, mg;
W - sampuli yakawanda, mg;
Nzira yacho yakaitwa katatu mukufanana uye avhareji yakatorwa, uye kukanganisa hakufaniri kudarika 0.3%.Chigadzirwa chemukati chinofanira kunge chiri> 99.0%.
3. Kunyunguduka: maererano ne-melting point determination method (Appendix VII C yeChinese Pharmacopoeia 2010 edition), nzvimbo inonyunguduka yechigadzirwa ichi inofanira kuva 110.0 ~ 115.0 ℃.
4. Kutsunga kwehuwandu hwemvura: maererano nenzira yekuyera kunyorova (KF nzira) yekuona, mvura yechigadzirwa ichi inofanira kuva <0.50%.
5. Kuchengeta: Chengetedza munzvimbo ine rima uye inotonhorera yakaoma (<5 ℃).
6. Kudzokorora nguva: gore rimwe

Synthetic nzira:

Zvakanakira:

Yakakwana Capacity: Inokwana zvivakwa uye matekiniki

Professional Service: Imwe inomira kutenga sevhisi

OEM Package: Tsika pasuru uye label iripo

Fast Delivery: Kana iri mukati me stock, mazuva matatu ekutumira anovimbiswa

Yakagadzika Supply: Chengetedza zvine musoro stock

Tsigiro yehunyanzvi: Tekinoroji mhinduro iripo

Tsika Synthesis Service: Kubva pamagiramu kusvika makirogiramu

Hunhu Hwepamusoro: Yakagadzira yakakwana yemhando yekusimbisa system

FAQ:

Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.

Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.

Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.

HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.

Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.

Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.

MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.

Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.

Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.

Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.

Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.

Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.

25952-53-8 - Njodzi uye Kuchengeteka:

Risk Codes
R34 - Zvinokonzera kupisa
R36/37/38 - Kushungurudza maziso, kufema system uye ganda.
R41 - Ngozi yekukuvara kwakakomba kwemaziso
R37/38 - Inogumbura kune yekufema system uye ganda.
R20/21/22 - Inokuvadza nekufema, kubata neganda uye kana ikamedzwa.
Tsanangudzo Yekuchengetedza
S26 - Kana wasangana nemaziso, simbura nekukasira nemvura yakawanda uye tsvaga mazano ekurapwa.
S36/37/39 - Pfeka zvipfeko zvekudzivirira zvakakodzera, magurovhosi uye kudzivirira maziso/chiso.
S45 - Kana pakaitika tsaona kana ukanzwa usinganzwe zvakanaka, tsvaga zano rekurapa nekukasira (ratidza chinyorwa pese pazvinogoneka.)
S37/39 - Pfeka magirovhosi akakodzera uye dziviriro yeziso / kumeso
S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera.
UN IDs UN 2735 8/PG 3
WGK Germany 3
RTECS FF2200000
FLUKA BRAND F CODES 1-3-10
TSCA Y
HS Code 2925290090
Hazard Note Irritant
Toxicity LD50 intravenous in mouse: 56mg/kg

Application:

1-(3-Dimethylaminopropyl) -3-Ethylcarbodiimide Hydrochloride (EDC · HCl) (CAS: 25952-53-8) ichena crystalline poda, nyore kuparara, inonyunguduka mumvura, inonyunguduka mu ethanol, inoshandiswa se activating reagent ye carboxyl. mapoka ari muamide synthesis, anoshandiswawo kumisikidza phosphate mapoka, cross-linking yemapuroteni uye nucleic acids, uye kugadzirwa kwema immunocouplers.EDC-HCl inoshandiswa mu pH ye 4.0-6.0 uye inowanzoshandiswa pamwe chete neN-Hydroxysuccinimide (NHS) kana N-Hydroxysulfosuccinimide sodium munyu kuti ivandudze kubatanidza kushanda.
EDC·HCl is water-soluble carbodiimide, inoshandiswa zvakanyanya kubatanidza peptide.EDC·HCl inoshandiswa secarboxyl activating agent.Inoita basa rakakosha rekumisa kwema biomolecules makuru mukubatana neN-hydroxysuccinimide.Inoshandiswawo mu acylation ye phosphoranes.
Mvura-inonyungudika kubva kune carbodiimide inobatsira pakubatanidza haptens kumapuroteni uye polypeptides.Inoshandiswa kushandura maNMDA receptors uye seanotsikisa mumiriri mune peptide synthesis.Mukana wakakura wekubatanidza EDAC ndiko kubviswa kuri nyore kweyakawandisa reagent uye inoenderana urea nekugeza ne dilute acid kana mvura.Carbodiimides inokonzeresa kuumbwa kwemaamide bond, carboxylic acids, uye maamines nekuita kuti carboxylate iite O-acylurea.Iyi yepakati inogona kurwiswa neamine zvakananga kuita amide.EDAC inoburitswa seyakanyungudika urea kubva.
EDC · HCl inogona kushandiswa kugadzira amides.Inoshandiswa sechinhu chekubatanidza mukugadzirwa kwe esters kubva ku carboxylic acids uchishandisa dimethylaminopyridine sechinhu chinokonzera.
Kune kunyanya matatu anowanzo shandiswa condensing agents: DCC, DIC uye EDC·HCl.Kushandiswa kwerudzi urwu rwe condensing agent kazhinji kunoda kuwedzerwa kweacylation catalysts kana activators, zvakadai seDMAP, HOBt, etc. Sezvo kuwedzera kwepakati yeasidhi kune carbodiimide muchikamu chekutanga chekuita haina kugadzikana, kana acylation. catalyst haishandiswe kuishandura kuita ester inoshanda kana inoshanda amide, inozorongedzerwa kuita inowirirana yakagadzikana ne-chigadzirwa cheurea (Path B).Condensation activator: Kune anotevera marudzi eanowanzo shandiswa condensation activator.Parizvino, 4-N, N-dimethylpyridine (DMAP) yakashandiswa zvakanyanya kukonzeresa maitiro akasiyana acylation.Dzimwe nguva 4-PPY inogona kushandiswa kana iyo catalytic mhedzisiro yeDMAP isiri yakanaka.Zvinoenderana nemabhuku akakodzera, kugona kwayo kwekuita kunosvika chiuru chepamusoro kupfuura DMAP.pakati peatatu anowanzo shandiswa condenser, DCC neDIC zvakachipa.Kazhinji DCC neDMAP zvinoshandiswa pamwechete.Chimwe chezvakanyanya kuipa pakushandisa DCC ndechekuti chimwe chigadzirwa chemhinduro, dicyclohexylurea, ine kunyungudika kudiki mune yakajairika organic chikamu asi inonyungudika zvishoma, saka zvinonetsa kuibvisa zvakakwana kuburikidza nedzimwe dzinowanzoshandiswa nzira dzekuchenesa, recrystallization. column chromatography, nezvimwewo;nekuti kunyungudika kwe dicyclohexylurea mu ether kudiki pane zvimwe zvinonyungudutsa, saka, kurapwa kwerudzi urwu rwekuita kunowanzo bvisa iyo reaction solvent uye inowedzera ether, uye kusefa yakawanda ye dicyclohexylurea isati yawedzera kurapwa.Nekuti diisopropylurea inogadzirwa neDIC ine kunyungudika kuri nani mune zvakajairika organic zvinonyungudutsa, inowanzoshandiswa mucombinatorial chemistry solid-phase synthesis.EDCI parizvino inoshandiswa zvakanyanya mumakemikari ekurapa.Imwe yeayo hunhu hukuru ndeyekuti iyo urea inogadzirwa mushure mekuita inonyungudika nemvura uye iri nyore kugezwa.Kazhinji, EDCI inosanganiswa neHOBt (chinyorwa: iyi maitiro HOBt inowanzokosha, zvikasadaro inogona kutungamira kune yakaderera condensation goho).Dzimwe nguva kana iyo-chinzvimbo chipingamupinyi cheasidhi yakakura kana paine boka rekubvisa maerekitironi, mhinduro icharamba iri munhanho inoshanda ester (iyo inoshanda ester ine yakasimba mass spectrum chiratidzo uye inogona kuonekwa neMS kana LC-MS).