Entecavir CAS 142217-69-4 API Factory High Quality Anti-HBV
Mugadziri Wekutengesa ane Kuchena Kwepamusoro uye Hunhu Hwakagadzikana
Zita reKemikari: Entecavir
CAS: 142217-69-4
Antiviral mushonga unoshandiswa mukurapa Hepatitis B Infection
API High Quality, Commercial Production
Chemical Name | Entecavir |
Mashoko anoreva zvakafanana | 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopenyl]-6H-purin-6-imwe |
Nhamba yeCAS | 142217-69-4 |
Nhamba yeCAT | RF-API80 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
Molecular Formula | C12H15N5O3 |
Molecular Weight | 277.28 |
Melting Point | 249.0~252.0℃ |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | White Crystalline Powder |
Kuzivikanwa IR | Iyo infraed absorption spectrum yemuyedzo sampuli inofanirwa kuenderana nereferensi chiyero |
Kuzivikanwa HPLC | Nguva yekuchengeta yemuenzaniso webvunzo inoenderana neiyo yereferensi mwero |
pH | 5.5~7.5 |
Specific Optical Rotation | +24.0°-+28.0° (DMF: MeOH=1:1 C=1%) |
Related Substances | |
Zvose Zvisina Kuchena | ≤0.30% |
Maximum Single Kusachena | ≤0.10% |
Enantiomer | ≤0.20% |
Residual Solvents | |
Methanol | ≤0.30% |
Dichloromethane | ≤0.06% |
n-Hexane | ≤0.029% |
Tetrahydrofuran | ≤0.072% |
N, N-Dimethylformamide | ≤0.088% |
Toluene | ≤0.089% |
Mvura Yemukati | 5.8%~6.5% |
Residue paIgnition | ≤0.10% |
Heavy Metals | ≤20ppm |
Assay | 98.0% ~ 102.0% (C12H15N5O3 yakaverengerwa pane anhydrous basis) |
Particle Size | D90: ≤100µm |
Test Standard | Enterprise Standard |
Usage | API, Antiviral drug inoshandiswa mukurapa Hepatitis B Infection |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Entecavir chizvarwa chitsva cheguanine nucleoside analogues mushonga wemuromo wekurapa kweHepatitis B Virus (HBV) utachiona, kunyanya kurapwa kwevarwere vakuru vane hutachiona hwekudzokorora basa uye serum transaminase yakaramba ichiwedzera, kana chiropa chechiropa chechirwere chechirwere chechirwere chisingaperi chehepatitis B. , pari zvino hutachiona huri pasi hunokurumidza uye hune simba zvakanyanya, mwero wekuchinja wakaderera nucleoside analogues.Dhiyabhorosi inoratidza kuti zvakasiyana nevarwere vane chirwere chisingaperi chehepatitis B, kusanganisira nucleoside naive uye nucleoside yakabatwa uye chiropa chechirrhosis varwere, kushandisa zvakanaka mahwendefa entecavir mukurapa kunogona kudzora chirwere chacho nokukurumidza uye nyore kusvika pakurapa kwechokwadi kuguma, kureva hutachiona hweH hepatitis B husingaenzaniswi;kuburikidza nekuomerera kukurapa, chikamu chikuru chevarwere chinogona kusvika pamagumo ekugutsikana kwekurapa, kureva e antigen serology kutendeuka, vamwe varwere vanogona kutosvika kune yakanakira kurapwa kwekupedzisira, iyo inonzi surface antigen negative.