Epalrestat CAS 82159-09-9 Kuchena > 99.5% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira kugadzira Epalrestat (CAS: 82159-09-9) ine mhando yepamusoro.Ruifu Chemical inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, madiki uye akawanda akawanda aripo.Tenga Epalrestat,Please contact: alvin@ruifuchem.com
| Chemical Name | Epalrestat |
| Mashoko anoreva zvakafanana | Epalrest;ONO-2235;Eabeth;Kinedak;Sorbistat;(5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-Thiazolidineacetic Acid;2- [(5Z)-5-[(E)-3-Phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic Acid;(E,E) -2-[5-(2-Methyl-3-phenyl-prop-2-enyldene)-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic Acid |
| Stock Status | MuStock, Mass Production |
| Nhamba yeCAS | 82159-09-9 |
| Molecular Formula | C15H13NO3S2 |
| Molecular Weight | 319.39 g/mol |
| Melting Point | 222.0 kusvika 226.0 ℃ |
| Density | 1.43±0.10 g/cm3 |
| Solubility | DMSO 2 mg/mL Mvura <1 mg/mL Ethanol <1 mg/mL |
| Storage Temp. | Nzvimbo Inotonhorera & Yakaoma (-20 ℃) |
| COA & MSDS | Available |
| Category | API |
| Brand | Ruifu Chemical |
| Items | Kuongorora Maitiro | Results |
| Chitarisiko | Orange kusvika Orange Red Crystalline Powder | Zvinoenderana |
| Identification | Zvakafanana neHPLC yekuchengetedza nguva yeyakajairwa | Pass |
| Melting Point | 222.0 kusvika 226.0 ℃ | 222.4~224.3℃ |
| Kurasika paKuomesa | <0.50% | 0.04% |
| Residue paIgnition | <0.20% | 0.03% |
| Masimbi anorema (Pb) | ≤20ppm | <20ppm |
| Zvose Zvisina Kuchena | ≤0.50% | 0.20% |
| Kuchena / Analysis Method | >99.5% (HPLC) | 99.8% |
| Infrared Spectrum | Inopindirana neChimiro | Zvinoenderana |
| Mhedziso | Chigadzirwa chacho chakaedzwa uye chinoenderana nezvakapihwa | |
Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma (-20 ℃) yekuchengetera kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
UN IDs 2811
WGK Germany 3
RTECS XJ5131855
Njodzi Kirasi 6.1
Packing Group II
Epalrestat (CAS: 82159-09-9) ndiyo yechipiri aldose reductase inhibitor kuti iunzwe pasi rose uye yekutanga kutangwa muJapan.Epalrestat inoratidzirwa kurapwa kwechirwere cheshuga neuropathy.Iri zvakare kuongororwa nezvechirwere cheshuga retinopathy uye nephropathy.Epalrestat inonzi aldose reductase inhibitor ine IC50 ye72 nM.
Epalrestat inhibits Aldose Reductase (AR) inobatanidzwa muyero yekumisa nhanho mukushandurwa kweglucose ku sorbitol pasi pe hyperglycemic mamiriro.Aldose reductase yanga iri chinangwa chevakawanda vekiriniki vanoongorora kurapa chirwere cheshuga neuropathy uye retinopathy.Epalrestat mushonga unotenderwa muJapan neIndia, unoshandiswa kurapa chirwere cheshuga neuropathy.
Epalrestat inoshandiswa kudzivirira, kugadzirisa, uye kurapa peripheral neuropathy (kusanzwa, kurwadziwa), vibrational paresthesia, uye kusagadzikana kwemoyo kunoenderana nechirwere cheshuga.
Epalrestat semumiririri wayo wemishonga inoderedza intracellular kuunganidzwa kwefructose uye sorbitol nekudzoreredza inhibiting aldose reductase basa, inodzoreredza Na+-K+-ATPase uye inositol basa, inowedzera HAPANA kuumbwa muendothelial masero, inhibits protein kinase C chiratidzo nzira, endothelial high cell- adhesion. mediated neutrophil uye endothelial adhesion factor expression uye inoderedza carboxymethyl lysine zvigadzirwa muvarwere vane chirwere cheshuga, nokudaro kurapa zvirwere zvakadai seshuga uye zvinetso zvayo.
