Erlotinib Hydrochloride CAS 183319-69-9 Kuchena >99.0% (HPLC)

Tsanangudzo Pfupi

Kemikari Zita: Erlotinib Hydrochloride

Anoreva zvakafanana: Erlotinib HCl;Tarceva

CAS: 183319-69-9

Kuchena (HPLC): > 99.0%

Chitarisiko: Ichena kusvika Kure-Ichena Crystalline Powder

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Anotungamira mugadziri uye mutengesi weErlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-imwe CAS 179688-29-0
Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	Erlotinib Hydrochloride
Mashoko anoreva zvakafanana	Erlotinib HCl;Tarceva;CP-358774 Hydrochloride;6,7-Bis(2-methoxyethoxy) -4-(3-ethynylanilino)quinazoline Hydrochloride;N-(3-Ethynylphe nyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine HCl
Nhamba yeCAS	183319-69-9
Nhamba yeCAT	RF-PI2242
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C22H24ClN3O4
Molecular Weight	429.90
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Ichena kusvika kuOff-White Crystalline Powder
Identification	A: IR: Inopindirana neReference Spectrum B: HPLC: Inopindirana neReference RT
Solubility	Yakanyanya Kunyungudika MuMvura, Inonyungudika Zvishoma muMethanol uye Inoshanda Isingasviki muAcetonitrile, Acetone, Ethyl Acetate uye Hexane.
Melting Point	223.0~229.0℃
Kurasika paKuomesa	<0.50%
Residue paIgnition	<0.20%
Heavy Metals	<20ppm
Kusachena Kumwechete	<0.50%
Zvose Zvisina Kuchena	<1.00%
Residual Solvents
Pyridine	<4000ppm
Chloroform	<4000ppm
DMF	<3000ppm
Kuchena / Analysis Method	>99.0%
Assay / Analysis Method	98.5% ~ 101.0% (Yakarongwa paAnhydrous Basis)
Test Standard	Enterprise Standard
Usage	API

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

FAQ:

Application:

Erlotinib Hydrochloride (CAS: 183319-69-9) imorekuru diki re epidermal growth factor receptor tyrosine kinase reversible inhibitor, rinonyanya kushandiswa mukurapa kwenzvimbo yepamusoro kana metastatic isiri diki kenza yemapapu uye yechipiri-mutsara kana matatu mutsara kurapwa. pancreatic cancer.Erlotinib Hydrochloride yakatenderwa muna Mbudzi, 2004, kuitira kurapwa kwepamusoro kana metastatic isiri-diki-diki kenza yemapapu.Iyo ndeyekirasi imwechete seGefitinib, imwe quinazoline yakabvumidzwa kurapwa kwekenza yemapapu yepamusoro, asi ine yakagadziridzwa pharmacokinetic zvivakwa.Iyo morekuru yakavambwa naPfizer uye budiriro yakatangwa mukubatana neOSI, iyo yakatora kodzero dzakakwana kumushonga apo Pfizer akabatanidzwa naWarner Lambert.Zvadaro, Genentech/Roche yakapinda muchibvumirano cherezinesi neOSI kugadzira nekutengesa mushonga uyu muUS nePasi rose.Sarudza epidermal kukura factor receptor (EGFR) -tyrosine kinase inhibitor.Antineoplastic.Erlotinib Hydrochloride inhibitor yeHER1/EGFR ine IC50 ye2 nM.Erlotinib HCl inowanikwa se 25-, 100-, uye 150-mg mapiritsi ekutungamirira kwemuromo.