Fondaparinux Sodium CAS 114870-03-0 API
Supply with High Purity and Stable Quality
Kemikari Zita: Fondaparinux Sodium
CAS: 114870-03-0
An Antithrombotic Anticoagulant, Factor Xa Inhibitor
API High Quality, Commercial Production
Chemical Name | Fondaparinux Sodium |
Nhamba yeCAS | 114870-03-0 |
Nhamba yeCAT | RF-API84 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
Molecular Formula | C31H43N3O49S8.10Na |
Molecular Weight | 1728.08 |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika kuOff-White Powder |
Assay / Analysis Method | 95.0% ~ 103.0% (payakaomeswa) |
Solubility | Inonyungudika Zvakasununguka muMvura, 2.0M Sodium Chloride uye 0.5M Sodium Hydroxide uye Isinganyunguriki muEthanol |
Kuzivikanwa 13C-NMR | Resonances yeFondaparinux Sodium inofanira kuonekwa pa 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 103.9, pp76.7, pp.Kuchinja kweKemikari kwezvikwangwani izvi hakuna kusiyana nekupfuura ± 0.3ppm mamwe masaini ehurefu hwakasiyana uye kuchinja kwemakemikari, kunokonzerwa neFondaparinux Sodium, pamwe inoonekwa pakati pe58.0 ~ 80.5 ppm uye 98.7 ~ 104.5ppm. |
Kuzivikanwa HPLC | Nguva yekuchengetwa kwepamusoro pepamusoro pemhinduro yemuenzaniso inoenderana neiyo yemhinduro yakajairwa |
Kuzivikanwa AAS | Sodium inofanira kuva nehunhu hwekunyura pa330.2nm pasi pekugadzwa kwesodium |
pH | 6.0~8.0 |
Sodium (Na) | 11.5% ~ 15.0% (Yakaverengerwa pane anhydrous uye zvinonyungudutsa zvemahara) |
Free Sulfate | ≤0.30% |
Residual Chloride | ≤1.00% |
Related Substances | |
Kusachena A | ≤0.80% |
Kusachena B | ≤0.60% |
Single Other Kusachena | ≤0.30% |
Zvose Zvisina Kuchena | ≤2.00% |
Residual Solvents | |
Methanol | ≤3000ppm |
Ethanol | ≤5000ppm |
Ethyl Acetate | ≤5000ppm |
DMF | ≤880ppm |
Methylbenzene | ≤890ppm |
Pyridine | ≤50ppm |
Zvemumvura (KF) | ≤15.0% |
Bacterial Endotoxins | ≤3.3EU/mg |
Microbial Limit | Huwandu hwese hweMicroorganisms ≤100cfu/g |
Test Standard | Enterprise Standard;United States Pharmacopoeia (USP) Standard |
Usage | API, An Antithrombotic Anticoagulant, Factor Xa Inhibitor |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
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Fondaparinux Sodium (CAS 114870-03-0) ndiyo yekutanga yekirasi nyowani yeantithrombotic anticoagulant kemikari ine chekuita ne low molecular weight heparins (LMWH).Fondaparinux sodium chinhu Xa inhibitor kuumba yakakwira affinity inosunga saiti yeanti-coagulant factor antithrombin III (ATIII).Fondaparinux sodium inosunga panzvimbo ino inogonesa iyo yakasikwa inhibitory mhedzisiro yeATIII inopesana nefactor Xa nechinhu chingangoita mazana matatu, izvo zvinokonzeresa inhibition yechizvarwa chethrombin.Inotengeswa neGlaxoSmithKline.Chimiro chakagadzirwa neAlchemia chinotengeswa muUS naDr. Reddy's Laboratories.Fondaparinux sodium yakatanga kuunzwa muUS yekudzivirira yakadzika vein thrombosis iyo inogona kutungamirira kupulmonary embolism zvichitevera kuvhiyiwa kukuru kwemapfupa.Iyi molecule yakazara ikopi yeheparin pentasaccharide sequence, chimedu chipfupi chinokwanisa kukonzeresa antithrombin lllmediated inhibition ye factor Xa nokudaro ichivharira thrombin chizvarwa pasina antithrombin chiito.
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