Fondaparinux Sodium CAS 114870-03-0 API

Tsanangudzo Pfupi

Kemikari Zita: Fondaparinux Sodium

CAS: 114870-03-0

Chitarisiko: Muchena kusvika Kuchena-Upfu

Chiyero: 95.0% ~ 103.0% (paDried Basis)

An Antithrombotic Anticoagulant, Factor Xa Inhibitor

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Supply with High Purity and Stable Quality
Kemikari Zita: Fondaparinux Sodium
CAS: 114870-03-0
An Antithrombotic Anticoagulant, Factor Xa Inhibitor
API High Quality, Commercial Production

Chemical Properties:

Chemical Name	Fondaparinux Sodium
Nhamba yeCAS	114870-03-0
Nhamba yeCAT	RF-API84
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram
Molecular Formula	C31H43N3O49S8.10Na
Molecular Weight	1728.08
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Ichena kusvika kuOff-White Powder
Assay / Analysis Method	95.0% ~ 103.0% (payakaomeswa)
Solubility	Inonyungudika Zvakasununguka muMvura, 2.0M Sodium Chloride uye 0.5M Sodium Hydroxide uye Isinganyunguriki muEthanol
Kuzivikanwa 13C-NMR	Resonances yeFondaparinux Sodium inofanira kuonekwa pa 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 103.9, pp76.7, pp.Kuchinja kweKemikari kwezvikwangwani izvi hakuna kusiyana nekupfuura ± 0.3ppm mamwe masaini ehurefu hwakasiyana uye kuchinja kwemakemikari, kunokonzerwa neFondaparinux Sodium, pamwe inoonekwa pakati pe58.0 ~ 80.5 ppm uye 98.7 ~ 104.5ppm.
Kuzivikanwa HPLC	Nguva yekuchengetwa kwepamusoro pepamusoro pemhinduro yemuenzaniso inoenderana neiyo yemhinduro yakajairwa
Kuzivikanwa AAS	Sodium inofanira kuva nehunhu hwekunyura pa330.2nm pasi pekugadzwa kwesodium
pH	6.0~8.0
Sodium (Na)	11.5% ~ 15.0% (Yakaverengerwa pane anhydrous uye zvinonyungudutsa zvemahara)
Free Sulfate	≤0.30%
Residual Chloride	≤1.00%
Related Substances
Kusachena A	≤0.80%
Kusachena B	≤0.60%
Single Other Kusachena	≤0.30%
Zvose Zvisina Kuchena	≤2.00%
Residual Solvents
Methanol	≤3000ppm
Ethanol	≤5000ppm
Ethyl Acetate	≤5000ppm
DMF	≤880ppm
Methylbenzene	≤890ppm
Pyridine	≤50ppm
Zvemumvura (KF)	≤15.0%
Bacterial Endotoxins	≤3.3EU/mg
Microbial Limit	Huwandu hwese hweMicroorganisms ≤100cfu/g
Test Standard	Enterprise Standard;United States Pharmacopoeia (USP) Standard
Usage	API, An Antithrombotic Anticoagulant, Factor Xa Inhibitor

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.

Zvakanakira:

FAQ:

Application:

Fondaparinux Sodium (CAS 114870-03-0) ndiyo yekutanga yekirasi nyowani yeantithrombotic anticoagulant kemikari ine chekuita ne low molecular weight heparins (LMWH).Fondaparinux sodium chinhu Xa inhibitor kuumba yakakwira affinity inosunga saiti yeanti-coagulant factor antithrombin III (ATIII).Fondaparinux sodium inosunga panzvimbo ino inogonesa iyo yakasikwa inhibitory mhedzisiro yeATIII inopesana nefactor Xa nechinhu chingangoita mazana matatu, izvo zvinokonzeresa inhibition yechizvarwa chethrombin.Inotengeswa neGlaxoSmithKline.Chimiro chakagadzirwa neAlchemia chinotengeswa muUS naDr. Reddy's Laboratories.Fondaparinux sodium yakatanga kuunzwa muUS yekudzivirira yakadzika vein thrombosis iyo inogona kutungamirira kupulmonary embolism zvichitevera kuvhiyiwa kukuru kwemapfupa.Iyi molecule yakazara ikopi yeheparin pentasaccharide sequence, chimedu chipfupi chinokwanisa kukonzeresa antithrombin lllmediated inhibition ye factor Xa nokudaro ichivharira thrombin chizvarwa pasina antithrombin chiito.