Fulvestrant (ICI 182780) CAS 129453-61-8 API Factory High Quality

Tsanangudzo Pfupi

Zita: Fulvestrant (ICI 182780)

CAS: 129453-61-8

Chitarisiko: Ichena kusvika Kure-Ichena Crystalline Powder

Assay: 97.0% ~ 102.0% (pane yakaomeswa)

Fulvestrant inoshandiswa mukurapa kenza yemazamu yehomoni-sensitive muvakadzi vepomenopausal.

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

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Product Detail

Product Tags

Tsanangudzo:

Mugadziri Wekutengesa ane Kuchena Kwepamusoro uye Hunhu Hwakagadzikana
Zita: Fulvestrant
CAS: 129453-61-8
Fulvestrant inoshandiswa mukurapa kenza yemazamu yehomoni-sensitive muvakadzi vepomenopausal.
API High Quality, Commercial Production

Chemical Properties:

Chemical Name	Fulvestrant
Mashoko anoreva zvakafanana	(7α,17β) -7-[9-[(4,4,5,5,5-Pentafluorpentyl)sulfinyl]nonyl]estra-1,3,5(10)-trien-3,17-diol;ICI 182780
Nhamba yeCAS	129453-61-8
Nhamba yeCAT	RF-API81
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram
Molecular Formula	C32H47F5O3S
Molecular Weight	606.77
Melting Point	104.0~106.0℃
Solubility	Soluble muMethanol, Ethanol;Insoluble muMvura
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Ichena kusvika kuOff-White Crystalline Powder
Identification	By IR, HPLC
Specific Optical Rotation	+108.0 ° kusvika +115.0 °
Kurasika paKuomesa	≤0.50%
Residue paIgnition	≤0.10%
6-Keto-Fulvestrant	≤0.10%
6,7-Fulvestrant	≤0.10%
Fulvestrant Sulfone	≤0.20%
Fulvestrant Yakawedzerwa	≤0.30%
Fulvestrant sterol Dimmer	≤0.80%
Chero Munhu Mumwe Nemumwe Munhu Asina Kusvibiswa	≤0.10%
Zvose Zvisina Kuchena	≤1.0%
Fulvestrant A	42.0%~48.0%
Fulvestrant B	52.0%~58.0%
DMF	≤620ppm
Heavy Metals	≤10ppm
Assay	97.0% ~ 102.0% (payakaomeswa)
Storage	Chengetedza mumidziyo yakavharwa-inodzivirira chiedza chitoro chefiriji pa2 ~ 8 ℃
Test Standard	United States Pharmacopoeia (USP) Standard
Usage	Estrogen Receptor Antagonist

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.

Zvakanakira:

FAQ:

Application:

Fulvestrant (ICI-182780) CAS 129453-61-8, mushonga wejekiseni mhasuru wakagadzirwa nekambani yeAstraZeneca uye unoshandiswa mukurapa kenza yemazamu yehomoni-sensitive advanced muvakadzi vepamenopausal.Fulvestrant ndiyo yega antiestrogen mushonga inogona kushandiswa zvakanyanya kuchipatara zvichitevera kusabudirira kurapwa kwetamoxifen.Mushonga uyu imhando ye endocrine therapy, saka haizokonzeri chero yakaipa mhedzisiro inowanzoonekwa mune chemotherapy, ichipa kutevedzera kwakanaka kwemurwere.Miedzo yakawanda yemakiriniki yakawana kuti 250mg Fulvestrant inoshanda uye inogara yakachengeteka semutsara wechipiri wekurapa kenza yemazamu yepamusoro.Fulvestrant is a synthetic Estrogen Receptor (ER) Antagonist ine IC50 ye0.94 nM mune sero-isina assay.Fulvestrant zvakare induces autophagy uye apoptosis uye ine antitumor chiitiko.