Ganciclovir CAS 82410-32-0 API BW 759 GCV Antiviral CMV Inhibitor High Quality
Mugadziri Wekutengesa ane Kuchena Kwepamusoro uye Hunhu Hwakagadzikana
Zita reKemikari: Ganciclovir
CAS: 82410-32-0
Antiviral Agent yeKurapa kweCytomegalovirus (CMV) Infection
API High Quality, Commercial Production
Chemical Name | Ganciclovir |
Mashoko anoreva zvakafanana | GCV;BW 759;9- [[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine;2-Amino-9- (1,3-dihydroxypropan-2-yloxymethyl) -3H-purin-6-imwe;2'-Nor-2'-Deoxyguanosine |
Nhamba yeCAS | 82410-32-0 |
Nhamba yeCAT | RF-API82 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C9H13N5O4 |
Molecular Weight | 255.23 |
Melting Point | 250 ℃ |
Storage Temperature | 2-8℃ |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika kuOff-White Crystalline Powder |
Solubility | Yakanyanya Kunyungudika MuMvura |
Identification | Ultraviolet Absorption, Infrared Absorption |
Kurasika paKuomesa | ≤6.0% |
Residue paIgnition | ≤0.10% |
Related Substances | Ganciclovir Related Compound A ≤0.50% |
Muganhu weGuanine | ≤0.50% |
Residual Solvents (GC) | Ethanol ≤5000ppm |
Heavy Metals | ≤10ppm |
Absorption Coefficient | 516-548 pa252nm |
Bacterial Endotoxins | ≤0.84EU/mg |
Assay | 98.0%~102.0% (Titration) |
Test Standard | Enterprise Standard;United States Pharmacopoeia (USP) Standard |
Usage | API, CMV Inhibitor |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Ganciclovir (CAS 82410-32-0) ndeye nucleoside antiviral mishonga, iri rudzi rweguanosine derivatives.Ganciclovir inonzi parenterally-active antiviral agent inoratidzwa nokuda kwekuona- kana hupenyu hunotyisidzira cytomegalovirus (CMV) zvirwere muvarwere vasina immunocompromised.Iine yakakura-yakasiyana-siyana, yakakwirira-inoshanda inhibitory mhedzisiro paherpes virus uye ndiyo yekutanga-sarudzo mushonga wekurapa cytomegalovirus hutachiona hune simba rakasimba pahutachiona hwehepatitis B uye adenovirus zvakare.Ihomologue yeacyclovir (ACV) ine antiviral mhedzisiro yakafanana, asi yakasimba kupfuura aciclovir, ine zvakanyanya inhibitory mhedzisiro pa cytomegalovirus yakabatana nevarwere veAIDS.Ikiriniki inoshandiswa kurapa induction chikamu uye danho rekugadzirisa pavarwere vasina immunocompromised (kusanganisira varwere veAIDS) vane cytomegalovirus retinitis yakafanana.Inogonawo kushandiswa kudzivirira cytomegalovirus chirwere kune varwere vanogamuchira organ transplantation kana AIDS varwere vane migumisiro yakanaka cytomegalovirus serology bvunzo.
Ganciclovir (CAS 82410-32-0) inoshanda zvakanyanya, yakaderera-chepfu uye yakakwirira-selectivity virus inhibitor yakagadzirwa neSyntex Company (United States).Ndiwo mushonga wekutanga wakabvumidzwa neUS FDA kurapwa kwechirwere checytomegalovirus (CMV).Syntex yakapihwa kodzero yega yekugadzira.Muna Chikumi 1988, piritsi iri rakabvumidzwa kekutanga kunyorwa muUK, richiteverwa nekubvumidzwa zvakatevedzana neFrance, United States, Japan, neWest Germany, Italy neCanada nedzimwe nyika.Kusvika pakupera kwaChikumi 1999, yakabvumidzwa munyika dzinopfuura makumi manomwe uye matunhu ekudzivirira immunodeficiency varwere uye cytomegalovirus utachiona hwevarwere of organ transplantation.Muna 2002, mapiritsi eGanciclovir akawana mvumo kubva kuFDA, ave kuwanikwa izvozvi.