Gliepiride CAS 93479-97-1 Assay 98.0%~102.0% API Factory High Purity
Supply with High Purity and Stable Quality
Zita reKemikari: Glimepiride
CAS: 93479-97-1
Glimepiride mukurapa kweNoninsulin-Dependent Type 2 Diabetes Mellitus
API High Quality, Commercial Production
Chemical Name | Glimepiride |
Mashoko anoreva zvakafanana | Amaryl |
Nhamba yeCAS | 93479-97-1 |
Nhamba yeCAT | RF-API24 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C24H34N4O5S |
Molecular Weight | 490.62 |
Melting Point | 212.2~214.5℃ |
Shipping Condition | Under Ambient Temperature |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Upfu Huchena kana Hunenge Huchena |
Identification | IR (Yakafanana neStandard) |
Related Substances | |
Cis-Isomer (A) | ≤0.80% |
Sulfonamide (B) | ≤0.40% |
Urethane (C) | ≤0.10% |
3-Isomer (D) | ≤0.20% |
Chero Kumwe Kusachena | ≤0.10% |
Zvose Zvisina Kuchena | ≤0.50% |
Kurasika paKuomesa | ≤0.50% |
Residue paIgnition | ≤0.10% |
Heavy Metals | ≤0.001% |
Assay | 98.0%~102.0% |
Test Standard | European Pharmacopeia (EP);United States Pharmacopoeia (USP) |
Usage | Active Pharmaceutical Ingredient (API) |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weGlimepiride (CAS: 93479-97-1) ine mhando yepamusoro, inoshanda yemishonga yemishonga (API).Glimepiride mushonga weantidiabetic unobatsira kudzora mazinga eshuga.Gliepiride inogara kwenguva refu, yechitatu-chizvarwa sulfonylurea ine hypoglycemic chiitiko.
Glimepiride (zita rekutanga rekutengesa Amaryl) ndeye nemuromo inowanikwa yepakati-kusvika-yakareba-inobata sulfonylurea antidiabetic drug.Kufanana neyese sulfonylureas, glimepiride inoshanda se insulin secretagogue.Iyo inoderedza shuga yeropa nekukurudzira kuburitswa kwe insulin kubva mukushanda kwepancreatic beta masero uye nekuwedzera kunzwisiswa kweparipheral tishu kune insulin.Gliepiride inogona kunge inosunga kuATP-sensitive potassium chiteshi receptors pane pancreatic sero pamusoro, ichideredza potassium conduction uye kukonzera depolarization ye membrane.Membrane depolarization inoita kuti calcium ion iwedzere kuburikidza nemagetsi-sensitive calcium channels.Uku kuwedzera kweiyo intracellular calcium ion concentration inokonzeresa secretion ye insulin.Gliepiride inonyanya kushandiswa kurapa varwere vane Type 2 chirwere cheshuga uye inogona zvakare kuderedza mikana yekuti mumwe munhu aite matambudziko erudzi rwechipiri chirwere cheshuga.Mushonga uyu wakatenderwa neFDA muna 1995 uye unogadzirwa neSanofi-Aventis.Inogona kushandiswa pamwe chete nekudya kwakakodzera uye chirongwa chekurovedza muviri uye inogona zvakare kushandiswa yoga kana nemimwe mishonga yekurwisa chirwere cheshuga kana ichidikanwa.Gliepiride inogona kushandiswa kungave se monotherapy kana musanganiswa ne insulin.