H-Gly-OMe·HCl CAS 5680-79-5 Glycine Methyl Ester Hydrochloride Assay >99.0%

1. Properties: Ichi chigadzirwa chinofanira kuva chena crystalline upfu.
2. Muedzo:
1) Kutsunga kweGlycine Methyl Ester Hydrochloride assay
1.1 Nzira
Mumamiriro ezvinhu ane acidic, sampu inopindirana neimwe sirivha nitrate, uye iyo yakawandisa sirivha nitrate inodzoserwa neammonium thiocyanate, zvichireva ammonium ferric sulfate.
Sechiratidzo, iyo yakazara chlorine yemukati yakatemerwa zvichienderana nehuwandu hweyakajairwa mhinduro yakadyiwa, uye yakazara chlorine yemukati yakabviswa kubva pane zvirimo glycine hydrochloride kuwana Glycine Methyl Ester Hydrochloride zvirimo.
1.2 Reagents
Dibutyl phthalate;
Nitric acid solution: 2 + 3;
Silver nitrate standard titration solution: c(AgNO3) = 0.1 mol/L
Ammonium thiocyanate yakajairika titration mhinduro: c(NH4SCN) = 0.1 mol/L
Ammonium ferric sulfate (III) chiratidzo chemvura: 80 g/L
1.3 Analysis Procedure
Kuyera nezve 0.5g sampuli, yakarurama kusvika 0.0001g.Isa mu 250ml conical flask, nyungudusa mu 40ml mvura, wedzera 10 ml nitric acid solution, Wedzera (50 ± 0.02) mL silver nitrate standard titration solution, 3mL ammonium ferric sulfate indicator solution, 4mL dibutyl phthalate, uye thiocyanate solution yaiva thiocyanate Ammonium. titrated kusvikira mushonga wacho watsvukira uye wakaramba usina ruvara kwe30 s.
1.4 Mhedzisiro kuverenga
Chikamu chikuru che glycine methyl ester hydrochloric acid yemukati w1, iyo inoratidzwa se%, inoverengerwa maererano neEquation (1):
w1= (c1V1-c2V2)*M/1000/m * 100-w2 *1.126 fomula (1)
Kupi:
V1: Vhoriyamu yesirivheri nitrate yakajairwa titration mhinduro (ml)
V2: Vhoriyamu yeammonium thiocyanate yakajairika titration mhinduro inopedzwa netitration (ml)
c1: Kukosha chaiko kwesirivheri nitrate yakajairwa titration mhinduro (mol/L)
c2: Kukosha chaiko kweammonium thiocyanate standard titration solution (mol/L)
w2: Chikamu chemasa (%) che glycine hydrochloride yemukati sekutsanangurwa muChikamu 4.2
M: Molar mass ye glycine methyl ester hydrochloride (g/mol)
1.126: Shanduko coefficient ye glycine hydrochloride kuGlycine methyl ester hydrochloride.
Masvomhu anoreva kukosha kwezviyero zviviri zvakaenzana zvakatorwa semugumisiro wekuyera, uye musiyano wakakwana pakati pezviyero zviviri zvakada kufanana hazvina kudarika 0.05%.
2) Kutsunga kweglycine hydrochloride content
2.1 Nzira
Ichishandisa dimethyl yero sechiratidzo, sampu yakaverengerwa nesodium hydroxide standard titrating solution, uye vhoriyamu yemhinduro yakaderedzwa zvichienderana nekushandiswa kwesodium hydroxide standard.
Verenga iyo glycine hydrochloride yemukati.
2.2 Reagent
Standard titration solution ye sodium hydroxide: c (NaOH) = 0.1mol/L
Dimethyl yero inoratidza mvura: 10 g/L
2.3 Analysis Procedure
Weresa 5.0 g yemurabhoritari sampuli, yakarurama kusvika 0.0001g, mubeaker 200 ml, nyunguduka ne50ml mvura, uye wedzera madonhwe mashanu edimethyl.
Yellow indication liquid, ine sodium hydroxide standard titration solution titration kusvika mhinduro kubva kutsvuku kuenda kuorenji yero ndiyo yekupedzisira.
2.4 Mhedzisiro Kuverenga
Chikamu chikuru w2 che glycine hydrochloride yemukati chinoratidzwa se% uye chinoverengerwa maererano neEquation (2):
w2 =(V/1000)cM/m *100 formula (2)
Kupi:
V: Vhoriyamu ye sodium hydroxide standard titration solution (mL)
c: Kukosha chaiko kwesodium hydroxide standard titration solution concentration (mol/L)
M: Molar mass yeglycine hydrochloride (g/mol)
m: Kukosha kwehukuru hwemuenzaniso (g)
Masvomhu anoreva kukosha kwezviyero zviviri zvakaenzana zvakatorwa semugumisiro wekuyera, uye mutsauko wakakwana pakati pezviyero zviviri zvakaenzana hazvina kudarika 0.05%
3. Nzvimbo yakanyunguduka: Maererano nenzira yekugadzirisa nzvimbo yekunyunguduka (Chinese Pharmacopoeia 2010 Appendix VIC), nzvimbo yekunyunguduka ndeye 172-178 ºC.
4. Kuomesa uremu: tora chigadzirwa ichi pa105.0 ℃ uye woomesa kuti urambe uchirema.Kurasikirwa kwehuremu hakufaniri kudarika 0.5%.
5. Kuchengetedza: Ichi chigadzirwa chinofanira kuiswa mufiriji kure nechiedza.