Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Kuchena > 99.0% (HPLC)
Chemical Name | 3-(4-Phenoxyphenyl) -1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Mashoko anoreva zvakafanana | Ibrutinib yepakati N-2;Ibrutinib Deacryloylpiperidine;Ibrutinib Kusachena 8;5-(4-Phenoxyphenyl) -7H-pyrrolo[2,3-d]pyrimidin-4-ylamine;IBT4A;Ibrutinib N-Despiperidinyl Kusachena |
Nhamba yeCAS | 330786-24-8 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C17H13N5O |
Molecular Weight | 303.32 |
Melting Point | >262℃(Zvita) |
Density | 1.380±0.06 g/cm3 |
Hazard Kirasi | 6.1;Chepfu |
Packing Group | III |
COA & MSDS | Available |
Origin | Shanghai, China |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Off-White kune Khaki Powder |
Identification | HNMR, LC-MS |
Kuchena / Analysis Method | >99.0% (HPLC) |
Kurasika paKuomesa | <1.00% |
Single Max.Kusachena | <1.00% |
Zvose Zvisina Kuchena | <1.00% |
Heavy Metals (as Pb) | <20ppm |
Test Standard | Enterprise Standard |
Usage | Pakati peIbrutinib (CAS: 936563-96-1) |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro.
3-(4-Phenoxyphenyl) -1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS: 330786-24-8) inobatsira yepakati pekugadzira mukati mukugadzirwa kweIbrutinib (CAS: 936563-96-1 )Ibrutinib imhando yeBruton tyrosine kinase (BTK) inhibitor, inogona kushandiswa kurapa chronic lymphocytic leukemia (CLL) uye mantle cell lymphoma (MCL).MCL neCLL ndezveB-cell non-Hodgkin's lymphoma, iyo yakaoma kurapa uye nyore kudzokorora.Yakajairwa kemikari immunotherapy haina kunanga, inowanzoitika 3 kana 4 yakashata maitiro.Ibrutinib neB lymphocytes inogona kunanga neBTK iyo inofanirwa kuumbwa, kusiyanisa, uye kutapurirana kweruzivo, inhibit BTK chiitiko chisingachinjike, uye inhibit bundu cell kuwanda uye kurarama zvinobudirira.Ibrutinib inogona kukurumidza kunyura mushure mekutonga kwemuromo, panguva ye1 ~ 2h inosvika pahuwandu hwehuwandu hweropa, maitiro asina kunaka ndeemumwe kana maviri, saka, Ibrutinib ichava sarudzo itsva yekurapa kweCLL neMCL.