N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Yepakati Yakanyanya Kuchena
Commerce Supply Imatinib Mesylate uye Related Intermediates:
Imatinib Mesylate CAS: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS: 152460-09-8
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride CAS: 106261-49-8
| Chemical Name | N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine |
| Mashoko anoreva zvakafanana | Imatinib Mesylate Intermediate;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine |
| Nhamba yeCAS | 152460-09-8 |
| Nhamba yeCAT | RF-PI228 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C16H13N5O2 |
| Molecular Weight | 307.31 |
| Melting Point | 188.0~193.0℃ |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Yero kana Yero Hupfu |
| Kuchena | ≥98.0% (HPLC) |
| Kunyorova (KF) | ≤0.50% |
| Zvose Zvisina Kuchena | ≤2.0% |
| Maximum Single Kusachena | ≤1.0% |
| Residue pamoto | ≤0.50% |
| Heavy Metals | ≤20ppm |
| Test Standard | Enterprise Standard |
| Usage | Pakati peImatinib Mesylate (CAS: 220127-57-1) |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weN-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine (CAS: 152460-09-8) nemhando yepamusoro.Iyo yepakati kazhinji mune synthesis yeImatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate imorekuru diki rinovharira c-Abl protein-tyrosine kinase, Yakanyanya kurongeka yeBCR-ABL, iyo enzyme yakabatana nekusingaperi myelogenous leukemia (CML) uye mamwe mafomu eacute lymphoblastic leukemia (ALL).Chiitiko chekufambisa pakati pemakromosomes 9 ne22 chinoburitsa chromosome yePhiladelphia, iyo inobva yagadzira Bcr-Abl fusion protein ine aberrant kinase chiitiko chinosimudzira kukurumidza kuwanda kwesero.Imatinib Mesylate inosunga iyi yakakosha kinase, inomisa CML ine chekuita nekukura.Imatinib Mesylate yakaramba ichiratidzwa kuti inhibit PDGFR uye tyrosine kinases yakabatana ne c-Kit.Magadzirirwo ane Imatinib Mesylate akashandiswa mukurapa kwakasiyana kenza.
![4--[(4-Methylpiperazin-1-yl) methyl]benzoic acid dihydrochloride CAS 106261-49-8 Imatinib Mesylate Yepakati Yakanyanya Kuchena](https://www.ruifuchemical.com/uploads/d1fa2a19-300x300.jpg)