Indapamide CAS 26807-65-8 Purity ≥99.5% (HPLC) API EP Standard Factory High Quality
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weIndapamide uye inoenderana nepakati nemhando yepamusoro.
Indapamide CAS 26807-65-8
2-Methylindoline CAS 6872-06-6
1-Amino-2-Methylindoline Hydrochloride CAS 102789-79-7
| Chemical Name | Indapamide |
| Mashoko anoreva zvakafanana | N-(4-Chloro-3-Sulfamoylbenzamido)-2-Methylindoline |
| Nhamba yeCAS | 26807-65-8 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C16H16ClN3O3S |
| Molecular Weight | 365.83 |
| Melting Point | 160.0~162.0℃ |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kana Inenge Yakachena Crystalline Powder |
| Solubility | Inenge isinganyungudike mumvura;Soluble muEthanol |
| Identification A | Ultraviolet uye Inooneka Absorption Spectrophotometry |
| Kuzivikanwa B | Infrared Absorption Spectrophotometry |
| Chiziviso C | Thin-layer Chromatography |
| Optical Rotation | -0.80°~ +0.80° (C=5, C2H5OH) |
| Mvura (EP 2.5.12) | <3.00% |
| Sulphated Ash (EP 2.4.14) | <0.10% |
| Heavy Metals (EP 2.4.8) | <10ppm |
| Related Substances | |
| Kusachena B | <0.30% |
| Kusachena Kusingataurwi | <0.10% |
| Zvose Zvisina Kuchena | <0.50% |
| Kuchena / Analysis Method | >99.5% (HPLC) |
| Test Standard | EP Standard |
| Usage | API;Antihypertensive uye A diuretic |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro.
Indapamide (CAS: 26807-65-8) inonzi antihypertensive uye diuretic.Nekudzivisa Na + reabsorption pamagumo ekupedzisira e distal conflexion tubules, inobudisa diuretic effect uye inovharawo Ca2 + kupinda.Iyo ine yakakwira selectivity kune vascular smooth muscle, dilates peripheral midziyo midiki uye inoburitsa hypotensive effect.Asi mhedzisiro pavascular smooth tsandanyama yakasimba diuretic effect, iri pasi peiyo diuretic doses inogona kudzika-pasi, yakakwirira madosi yakaratidza diuretic effect, asi hapana thiazide diuretic kukanganisa, iyo isingakonzere orthostatic hypotension, flush uye reflective tachycardia, pamufananidzo weropa, metabolism yeropa. mafuta, shuga uye renal kushanda zvakare kwakanga kusina maitiro akajeka, kurapa kwemaitiro ekurova kwemwoyo, kubuda kwemwoyo, kusina kuchinja kukuru mu electrocardiogram (ecg) yakanga Haina mhedzisiro yakajeka pane central nerve system uye autonomic nerve.Oral administration ye2 ~ 3 chemicalbook H yakagadzira hypotensive effect, iyo yakachengetwa kwe24h.Diuretic effect yakaonekwa pa 3h uye yakasvika pakunyanya mhedzisiro pa4 ~ 6h.Indapamide yakakodzera kune yakapfava uye ine mwero yekutanga hypertension, inogona zvakare kushandiswa kune congestive moyo kukundikana kunokonzerwa nemvura sodium retention, nekutadza kwerenal kunoshandawo kune varwere vane BP, chirwere cheshuga, hyperlipidemia, shandisa antihypertensive effect inoshamisa.
