Inosine CAS 58-63-9 Assay 98.0~102.0% Fekitari Yepamusoro Hunhu
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weInosine (CAS: 58-63-9) ine mhando yepamusoro, inosangana nechiyero cheChinese Pharmacopoeia ChP2020 II.Zvigadzirwa zvedu zvinotengeswa zvakanyanya kuAmerica neEurope, India, uye makambani anozivikanwa emishonga muChina.Zvigadzirwa zvakawana mukurumbira wepamusoro mumisika yepasirese uye yemumba.Isu tinokwanisa kupa kuendesa pasirese, zvidiki uye huwandu hwakawanda huripo.Kana iwe uchifarira Inosine (CAS: 58-63-9),Please contact: alvin@ruifuchem.com
Chemical Name | Inosine |
Mashoko anoreva zvakafanana | (-)-Inosine;Hypoxanthine 9-β-D-Ribofuranoside;Hypoxanthine-9-beta-D-Ribofuranoside;Atorel;beta-Inosine;Hypoxanthine D-Riboside;1,9-Dihydro-9-β-D-Ribofuranosyl-6H-purin-6-imwe;Hypoxanthine Riboside;Hypoxanthine Ribonucleoside;9-β-D-Ribofuranosylhypoxanthine |
Stock Status | MuStock, Kukwanisa Kugadzira Matani makumi matatu pamwedzi |
Nhamba yeCAS | 58-63-9 |
Molecular Formula | C10H12N4O5 |
Molecular Weight | 268.23 |
Melting Point | 222.0~226.0℃(Zvita.) (lit.) |
Sensitive | Hygroscopic |
Solubility | Zvishoma Soluble muMvura, Insoluble muEthanol, uye Soluble in Dilute Hydrochloric Acid uye Sodium Hydroxide Solution. |
Kunhuwa | Kusina hwema |
Storage Temp. | Yakavharwa muKuoma, Chengetedza paChikamu Tembiricha |
COA & MSDS | Available |
Brand | Ruifu Chemical |
Hazard Codes | Xi - Irritant | RTECS | NM7460000 |
Risk Statements | 36/37/38 | F | 10 |
Safety Statements | 24/25-36-26 | TSCA | Ehe |
WGK Germany | 2 | HS Code | 2934993090 |
Items | Kuongorora Maitiro | Results |
Chitarisiko | White Crystals kana Crystalline Powder;Odorless;Inovava zvishoma | Conforms |
Identification | 1) Ratidza Positive Rection 2) Nguva Yekuchengeta Inopindirana neChiyero 3) Infraned Absorption | Conforms |
State of Solution (Transmittance) | ≥98.0% | Conforms |
Masimbi anorema (Pb) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
Kurasika paKuomesa | ≤1.00% (pa105 ℃ ye3 Maawa) | 0.40% |
Residue paIgnition (Sulfated) | ≤0.20% | 0.07% |
Related Substances | Hwose hutsvina pamusoro penzvimbo inodarika 1.0% yenzvimbo yekutarisa | Conforms |
Assay | 98.0 kusvika 102.0% | 99.4% |
pH Kukosha | 4.8 kusvika 5.8 (1.0g mu100ml yeH2O) | 5.0 |
Miedzo yeMicrobiological | ||
Total Aerobic Limits | ≤800CFU/g | 40CFU/g |
Total Mold Limits | ≤80 CFU/g | 10CFU/g |
Mbiriso | ≤80 CFU/g | 10CFU/g |
Escherichia Coli | Negative | Negative |
Mhedziso | Inosangana neChiyero cheChP2020 II |
Inosine (CAS: 58-63-9) ChP2020 Test Method
Inosine - DEFINITION
Zvinyorwa zveC10H12N4O5 zvichava pakati pe98.0% uye 102.0% yakaverengwa pane yakaomeswa chigadzirwa.
Inosine - Trait Ichi chigadzirwa ichena crystalline upfu;Kusina hwema.Ichi chigadzirwa chinonyungudika zvishoma mumvura, chisinganyungudika mu ethanol, uye chinonyungudika mu dilute hydrochloric acid uye sodium hydroxide solution.
Inosine - IDENTIFICATION
1. Tora chiyero chakanaka che 0.01% mhinduro yechigadzirwa ichi, wedzera huwandu hwakaenzana hwe3, 5-dihydroxytoluene solution (tora 3, 5-dihydroxytoluene uye ferric chloride 0.lg, wedzera hydrochloric acid kuita 100ml), sanganisa zvakanaka, mushure. kupisa mubhati remvura kwemaminitsi anenge gumi, ruvara rwegirini rwakaonekwa.
2. Mune chromatogram yakanyorwa pasi pechinhu chekutsunga chemukati, nguva yekuchengetedza yepamusoro-soro yemhinduro yekuedza inofanira kuenderana nekuchengetedza nguva yepamusoro-soro yemhinduro yereferensi.
3. Iyo infrared absorption spectrum yechigadzirwa ichi inofanira kuenderana neyekutonga (Spectrum set 605).
Inosine - Analysis
Transmittance of Solution
Tora 0.5g yechigadzirwa ichi, wedzera 50ml yemvura kuti inyunguduke, maererano neUV-inooneka spectrophotometry (General mutemo 0401), sarudza transmittance pa430nm wavelength, kwete pasi pe98.0%.(Yejekiseni)
Related Substances
Tora chigadzirwa ichi, wedzera mvura kunyunguduka uye dilute kuita mhinduro ine 0.5mg pa 1ml semuyedzo mhinduro;Tora 1ml yekuenzanisa kuyerwa, uise mu 100ml yekuyeresa flask, uidure nemvura kusvika pachiyero, sechigadziro chekutonga.Zvinoenderana nemamiriro echromatographic pasi pechinhu chekumisikidza chemukati, 20 u1 yebvunzo mhinduro uye yekudzora mhinduro inoteedzana mune yemvura chromatograph, uye iyo chromatogram inorekodhwa kaviri nguva yekuchengeta yepamusoro peak.Kana paine nhongonya dzehutsvina muchromatogram yemhinduro yebvunzo, huwandu hwenzvimbo yega yega yekusachena haizove yakakura kupfuura iyo huru nzvimbo yepamusoro yemhinduro yekudzora (1.0%).
Kurasika paKuomesa
Tora chigadzirwa ichi, chakaoma kuti chirambe chichirema pa 105 ° C, kurasikirwa kwehuremu hakufaniri kudarika 1.0% (General rule 0831).
Residue paIgnition (Sulfated)
Kwete kupfuura 0.1% (yejekiseni), kana kwete kupfuura 0.2% (yekushandisa nemuromo) (General mutemo 0841).
Heavy Metals
Tora chigadzirwa ichi 1.0g, kuongorora maererano nemutemo (General Principles 0821 mutemo wechipiri), ine heavy metals haifaniri kudarika zvikamu gumi pamiriyoni.
Abnormal Toxicity
Tora chigadzirwa ichi, wedzera sodium chloride jekiseni kunyungudutsa uye dilute mhinduro ine inosine 10mg pa 1ml, tarisa maererano nemutemo (General mutemo 1141), anofanira kutevedzera gadziriro.(Yejekiseni)
Inosine - Kutsunga kwemukati
Kuyerwa neHigh Performance Liquid Chromatography (General 0512).
Chromatographic mamiriro uye system kukodzera bvunzo silica gel yakasungwa negumi nemasere alkyl silane yakashandiswa sekuzadza;Methanol-mvura (10:90) yakashandiswa sechikamu chinotakurika;Iyo yekuona wavelength yaive 248nm.Tora inenge 10mg yeinosine reference, wedzera 1 mol/L hydrochloric acid solution (1ml), kupisa mumvura yekugeza pa80 ℃ kwemaminitsi gumi, rega itonhore, woisa 1ml ye1 mol/L sodium hydroxide solution, isa mvura ku50ml, 20u1 jekiseni remvura chromatograph, gadzirisa chromatographic system, dhigirii rekuparadzanisa yeinosine peak uye peak peak yekusachena inofanira kusangana nezvinodiwa, nhamba yetioretical plate zvinoenderana neinosine peak kuverenga haisi pasi pe2000.
Assay
Tora huwandu hwakakodzera hwechigadzirwa ichi, uiremedze nemazvo, wedzera mvura kuti inyunguduke uye uwedzere kunyorovesa kuti ugadzire mhinduro ine anenge 20ug pa lml, zunza, uye uishandise semhinduro yekuyedza, A 20ul jekiseni mvura chromatograph yakayerwa nemazvo uye. chromatogram yakanyorwa.Nhamba yakakodzera yeinosine referensi yakayerwa nemazvo uye yakatemwa nenzira imwechete, uye nzvimbo yepamusoro yakaverengerwa maererano nekunze kwemaitiro nzira.
Inosine - Category
Sero metabolism kunatsiridza zvinodhaka.
Inosine - Kuchengeta
Chiedza chekudzivirira, chisimbiso chekuchengetedza.
Pharmaceuticals: (1) Inosine Oral Solution (2) Inosine Tablets (3) Inosine Jekiseni (4) Inosine Capsules (5) Inosine uye Glucose Jekiseni (6) Inosine uye Sodium Chloride Jekiseni (7) Inosine yeJekiseni
Package: Fluorinated Bhodhoro, 25kg/bhegi, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera, yakaoma uye inofefetera kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
1. Inosine (CAS: 58-63-9), sechinhu che nucleoside, inonyanya kushandiswa kugadzira mishonga yekurapa zvirwere zvehutachiona uye zvimwe zvirwere.
2. Inosine is a non-canonical nucleotide inonyanya kuwanikwa se monophosphate.Inokwanisa kumisa pair ne deoxythymidine, deoxyadenosine uye deoxyguanosine.Kubatanidzwa kweinosine panzvimbo yeguanine kunogadzirisa zviitiko zvekushandura.Inosine ine antioxidant, anti-inflammatory uye neuroprotective functionality.Inosine inonyorerwa sekuwedzera kwekurapa kwekukuvara kwetsinga, kuzvimba uye oxidative kusagadzikana.Inogadzirisa maitiro ehupenyu kuburikidza neadenosine receptors.Iyo inowedzera neurite kubuda mukuora mwoyo kusagadzikana kuburikidza neadenosine receptors.Inosine inoshandiswawo kurapa sepsis muzvirwere.
3. Inosine chinhu chakakosha chemuviri wemunhu, rudzi rwecoenzyme mushonga unoshandiswa zvakanyanya mumishonga uye indasitiri yechikafu.Inogona kupinda musero remusero musero remuviri zvakananga, uye kuita kuti sero rive mumamiriro ekushaya simba uye anoxia irambe ichiita metabolize zvakanaka.Uye inogona kumisa caetone acid oxides, uye kutora chikamu cheprotein yemuviri mukugadzira.
Kushandiswa kweInosine Pharmaceuticals, yakadai seInosine Tablets uye Inosine Jekiseni
1. Inoshandiswa mukurapa leukopenia uye thrombocytopenia.
2. Mukurapa kwechirwere chehepatitis uye chisingaperi hepatitis uye chiropa chechiropa, hepatic encephalopathy.
3. Inoshandiswa kune coronary atherosclerotic heart disease (coronary heart disease), myocardial infarction, rheumatic heart disease, cor pulmonale axiliary drug use.
4. Inoshandiswa kudzivirira uye kuderedza mishonga yekudzivirira schistosomiasis inokonzerwa nemoyo uye huturu hwechiropa.
5. Inoshandiswa kune zvirwere zvemaziso (central retinal inflammation, optic atrophy) kushandiswa kwemishonga yekubatsira.
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