Irbesartan CAS 138402-11-6 Kuchena > 99.0% (HPLC) API Factory Antihypertensive
Manufacturer Supply, High Purity, Commercial Production
| Chemical Name | Irbesartan |
| Mashoko anoreva zvakafanana | BMS-186295;SR-47436;Aprovel;Avapro;2-Butyl-3-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-- 4-mumwe;2-Butyl-3-[[4--[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one |
| Nhamba yeCAS | 138402-11-6 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C25H28N6O |
| Molecular Weight | 428.54 |
| Density | 1.30±0.10 g/cm3 |
| Solubility mumvura | Insoluble muMvura |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Hunhu | Ichena kusvika Kuchena Crystalline Powder, Inonyungudika zvishoma mudoro uye mumethylene chloride, isinganyungudika mumvura. |
| Kuzivikanwa Infrared Absorption | Iyo IR spectrum inoenderana neyakaonekwa yakawanikwa neIrbesartan RS |
| Identification 2 | Nguva yekuchengetedza yepamusoro peak muchromatogram yeassay inoenderana neIrbesartan RS. |
| Kuchena / Analysis Method | >99.5% (HPLC) |
| Mvura | <0.50% |
| Heavy Metals | <0.002% |
| Residue paIgnition | <0.10% |
| Related Substances | (NeHPLC) |
| USP Kusachena A | <0.20% |
| Chero Kusazivikanwa Kusingazivikanwe | <0.10% |
| Zvose Zvisina Kuchena | <0.50% |
| Organic VolatileImpurities | Inosangana nezvinodiwa neUSP |
| Residual Azide | <10ppm |
| Residual Solvents | (NeGC) |
| Ethanol | <5000ppm |
| Toluene | <890ppm |
| Dichloromethane | <3000ppm |
| N, N-Dimethylformamide | <880ppm |
| T-Butyl Methyl Ether | <5000ppm |
| Assay | 98.0 ~ 102.0% (yakaverengerwa pane anhydrous basis) |
| Test Standard | Enterprise Standard;USP Standard |
| Usage | API;Antihypertensive;Zvekurapa hypertension |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro
Irbesartan (CAS: C) ndeye angiotensin II receptor antagonist inoshandiswa zvakanyanya kurapa hypertension.Irbesartan yakagadzirwa neSanofi Research (ikozvino chikamu cheSanofi-Aventis).Inotengeswa pamwe chete neSanofi-Aventis neBristol-Myers Squibb pasi pemazita ekutengeserana Aprovel, Karvea, uye Avapro.Irbesartan inoshandiswa kurapa BP.Avapro yakatangwa muGermany, UK uye US yehypertension.Sezvineiwo neangiotensin II receptor antagonists, irbesartan inoratidzwa pakurapa hypertension.Irbesartan inogonawo kunonoka kufambira mberi kwechirwere cheshuga nephropathy uye inoratidzirwawo kuderedza kufambira mberi kwechirwere chetsvo muvarwere vane chirwere cheshuga chechipiri, hypertension uye microalbuminuria (> 30 mg / 24 maawa) kana proteinuria.Irbesartan inogona zvakare kuderedza kugadziridzwa kwemagetsi kwemyocardium, nekudaro kuderedza huwandu hwekufa kwevarwere vane hypertension, ndiwo mushonga unoshanda kwazvo pakurapa hypertension uye chirwere chemoyo.
