L-(-)-Tyrosine CAS 60-18-4 (H-Tyr-OH) Chiyero 98.5~101.5% Factory High Quality

L-(-)-Tyrosine (H-Tyr-OH) (CAS: 60-18-4) AJI 97 Test Method
Kuzivikanwa: Enzanisa infrared absorption spectrum yemuenzaniso neiyo yechiyero ne potassium bromide disc nzira.
Chaiyo Kutenderera [α]20/D: Yakaomeswa Sample, C=5, 1mol/L HCl
State of Solution (Transmittance): 0.5g mu10ml ye1mol/L HCl, spectrophotometer, 430nm, 10mm sero ukobvu.
Chloride (Cl): 0.7g, A-1, ref: 0.40ml ye0.01mol/L HCl
Ammonium (NH4): B-2
Sulfate (SO4): 1.2g, (1), ref: 0.50ml ye0.005mol/L H2SO4
Simbi (Fe): 1.5g, (2), ref: 1.5ml yeIron Std.(0.01mg/ml)
Heavy Metals (Pb): 2.0g, (2), ref: 2.0ml yePb Std.(0.01mg/ml)
Arsenic (As2O3): 2.0g, (2), ref: 2.0ml yeAs2O3 Std.
Mamwe maAmino Acids: Dilute ammonia R2 Test Sample: 50μg, F-6-a, control: L-Tyr 0.25μg
Kurasikirwa paKuomesa: pa105 ℃ kwemaawa matatu.
Residue paIgnition (Sulfated): AJI Muedzo 13
Chiyero: Sample yakaomeswa, 180mg, (1), 6ml yeformic acid, 50ml yeglacial acetic acid, 0.1mol/L HCLO4 1ml = 18.119mg C9H11NO3
pH Muedzo: 0.02g mu100ml yakazara aqueous mhinduro

L-(-)-Tyrosine (H-Tyr-OH) (CAS: 60-18-4) USP35 Test Method
DEFINITION
Tyrosine ine NLT 98.5% uye NMT 101.5% yeL-Tyrosine (C9H11NO3), yakaverengerwa pane yakaomeswa.
KUZIVA
A. INFRARED AVORPTION <197K>
ASSAY
PROCEDURE
Muenzaniso: 180 mg yeTyrosine
Chisina chinhu: Sanganisa 6 mL yeformic acid uye 50 mL yeglacial acetic acid.
Titrimetric system
(Ona Titrimetry <541>)
Mode: Direct titration
Titrant: 0.1 N perchloric acid VS
Endpoint kuona: Potentiometric
Ongororo: Dissolve Sample mu6 mL yeformic acid uye 50mL yeglacial acetic acid, uye titrate neTitrant.Ita kusarudzika.
Verenga iyo muzana ye tyrosine (C9H11NO3) muSample yakatorwa:
Mhedzisiro = {[(VS-VB) x N x F]/W} x100
VS = vhoriyamu yeTitrant inopedzwa neSample (mL)
VB = vhoriyamu yeTitrant inopedzwa neiyo Blank (mL)
N = hunhu chaihwo hweTitrant (mEq/mL)
F= equivalency factor, 181.2 mg/mEq
W = uremu hwemuenzaniso (mg)
Maitiro ekugamuchira: 98.5% ~ 101.5% pane yakaomeswa hwaro
KUSIRIRA
RESIDUEON IGNITION <281>: NMT 0.4%
CHLORIDE NESULFATE, Chloride <221>
Mushonga wakakwana: 0.20mL ye0.020 N hydrochloric acid
Muenzaniso: 0.35 g yeTyrosine.[Cherechedza-Kana zvichidikanwa, nyungudutsa Sample nekudziya kusvika pedyo nekufashaira uye kuwedzera 1 mL yenitric acid.]
Maitiro ekugamuchira: NMT 0.04%
CHLORIDE UYE SULFATE, Sulfate <221>
Mushonga wakajairika: 0.50mL ye0.020 N sulfuric acid
Muenzaniso: 1.2 g yeTyrosine.[Cherechedza-Kana zvichidikanwa, nyudza Sample nekuwedzera 6 mL yediluted hydrochloric acid.]
Maitiro ekugamuchira: NMT 0.04%
IRON <241>: NMT 30ppm [Cherechedza-Kana zvichidikanwa, shandisa 2 mL yehydrochloric acid kunyungudutsa Sample.]
METALS ZVIKURU, Nzira I <231>: NMT 15ppm
RELATED COMPOUNDS
Diluted ammonia solution: Diluted 16 mL ye concentrated ammonia nemvura kusvika ku100 mL.
System suitability solution: Dissolve 10 mg yeUSP L-Tyrosine RS uye 10 mg yeUSP L-Phenylalanine RS mu 1 mL yeDiluted ammonia solution, uye dilute nemvura kusvika pa25.0 mL.
Mushonga wakajairika: Mubhokisi rakakodzera, nyungudutsa huwandu hweUSP L-Tyrosine RS mu1 mL yeDiluted ammonia solution.Dilute nemvura kusvika kuhuwandu kuwana mhinduro ye 0.05mg/mL.[Cherechedza-Iyi mhinduro ine kusungwa kwakaenzana ne0.5% yeiyo yeSample solution.]
Sample solution: Tumira 0.1 g yeTyrosine mu10-mL volumetric flask, wedzera yakakwana Diluted ammonia solution yekunyunguduka, uye wedzera nemvura kusvika kuhuwandu.
Chromatographic system (Ona Chromatography <621>, Thin-Layer Chromatography.)
Modhi: TLC
Adsorbent: 0.25-mm layer yechromatographic silica gel musanganiswa
Kushandiswa kwevhoriyamu: 5μL
Kugadzira solvent system: Isopropyl doro uye ammonium hydroxide (7: 3)
Spray reagent: 2 mg/mL yeninhydrin mumusanganiswa webutyl doro uye 2N acetic acid (95:5)
Kukodzera kwehurongwa
Zvinodiwa zvekukodzera: Iyo chromatogram yeSystem yekukodzera mhinduro inoratidza maviri akapatsanurwa mavara.
Analysis
Samples: Kukodzera kweSistimu mhinduro, Yakajairwa mhinduro, uye Sample mhinduro.
Pukuta ndiro pakati pe100 ° ne105 ° kusvikira ammonia yanyangarika zvachose.Pfaya neSpray reagent, wopisa pakati pe100° ne105° kwemaminetsi gumi nemashanu.Ongorora ndiro pasi pechiedza chichena.
Maitiro ekugamuchira: Chero nzvimbo yechipiri yeSample solution haina kukura kana kusimba kupfuura nzvimbo huru yeStandard solution.
Chero tsvina Yemunhu: NMT 0.5%
Yese tsvina: NMT 2.0%
ZVIYEDZO ZVAKANAKA
OPTICAL kutenderera, Chaiyo Rotation <781S>
Sample solution: 50 mg/mL mu 1 N hydrochloric acid
Maitiro ekugamuchira: -9.8 ° kusvika -11.2 °
LOSSON PAKUOMESA <731>: Pukuta sampuli pa105℃ kwe3 h: inorasikirwa neNMT 0.3% yehuremu hwayo.
ZVIMWE ZVINODIWA
PACKAGE AND STORAGE: Chengetedza mumidziyo yakavharwa zvakanaka.
USP REFERENCE MITIRO <11>
USP L-Phenylalanine RS
USP L-Tyrosine RS