Lasofoxifene Tartrate CAS 190791-29-8 Chiral Purity ≥99.0% Purity ≥98.0% (HPLC) API High Purity
Mugadziri Wekutengesa ane Kuchena Kwepamusoro uye Hunhu Hwakagadzikana
Kemikari Zita: Lasofoxifene Tartrate
CAS: 190791-29-8
Lasofoxifene Tartrate (CAS: 190791-29-8) mukurapa kwePostmenopausal Osteoporosis
Chemical Name | Lasofoxifene tartrate |
Mashoko anoreva zvakafanana | (5R,6S) -5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl) ethoxy]phenyl] -2-naphthalenol Tartrate Oporia |
Nhamba yeCAS | 190791-29-8 |
Nhamba yeCAT | RF-API20 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
Molecular Formula | C28H31NO2.ClH |
Molecular Weight | 450.019 |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika kuOff-White Powder |
Kunyorova (KF) | ≤0.50% |
Heavy Metals | ≤20ppm |
Chiral Purity | ≥99.0% |
Kuchena / Analysis Method | ≥98.0% (HPLC) |
Kurasika paKuomesa | ≤0.50% |
Residue paIgnition | ≤0.50% |
Test Standard | Chinese Pharmacopoeia (CP);Enterprise Standard |
Usage | Active Pharmaceutical Ingredient (API);Postmenopausal Osteoporosis |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weLasofoxifene Tartrate (CAS: 190791-29-8) ine mhando yepamusoro.
Lasofoxifene Tartrate ndeyechitatu-chizvarwa, isiri-steroidal inosarudza estrogen receptor modulator (SERM).Iyo inosarudza inosunga kumunhu ERalpha ine IC50 kukosha kwe1.5 nM uye inhibits kurasikirwa kwemapfupa mumakonzo ane ovariectomized.Muzvidzidzo zvemakiriniki zve postmenopausal osteoporosis, 0.5 mg / zuva lasofoxifene yakabatanidzwa nenjodzi dzakaderedzwa dze nonvertebral uye vertebral fractures, ER-positive kenza yemazamu, chirwere chemwoyo, uye sitiroko asi kuwedzera kwengozi yezviitiko zvevenous thromboembolic.Lasofoxifene yakaratidzawo kuita seanverse agonist paCB2 cannabinoid receptor, zvichiratidza kugona kwayo kudzokororwa semushonga wezviratidzo umo CB2 inotarisirwa.