Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0~102.0% Factory

Tsanangudzo Pfupi

Kemikari Zita: Lenvatinib Mesylate

CAS: 857890-39-2

Chiyero: 98.0 ~ 102.0%

Chitarisiko: Ichena kusvika Kuchena-Ichena Powder kana Makristasi

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Ruifu Chemical Supply Lenvatinib Mesylate Inopindirana Nekuchena Kwakanyanya
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Chemical Properties:

Chemical Name	Lenvatinib Mesylate
Mashoko anoreva zvakafanana	4- [3-Chloro-4-[(cyclopropylaminocarbonyl)amino]phenoxy]-7-Methoxy-6-Quinolinecarboxamide Mesylate;E 7080 Mesylate;Lenvima
Nhamba yeCAS	857890-39-2
Nhamba yeCAT	RF-PI1975
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C21H19N4O4Cl.CH4O3S
Molecular Weight	522.96
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Ichena kusvika kuOff-White Powder kana Makristasi
Identification	By IR;By UV;By HPLC
Solubility	Zvishoma Soluble mumvura, Practically Insoluble muEthanol
Melting Point	228.0~230.0℃
Zvemumvura (KF)	<1.00%
Residue paIgnition	<0.10%
Heavy Metals	<20ppm
Related Substances
Chero Kusachena Kumwe	<0.50%
Zvose Zvisina Kuchena	<1.00%
Assay / Analysis Method	98.0 ~ 102.0% (HPLC Basis on Drying)
Bulk Density	0.40gm/ml ~ 0.60gm/ml
Test Standard	Enterprise Standard
Usage	API

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

FAQ:

Application:

Lenvatinib Mesylate (CAS: 857890-39-2) inhibitor yemuromo uye yakawanda-inotarirwa yeVEGFR1-3, FGFR1-4, PDGFR, KIT, uye RET, ine mabasa ane simba antitumor.Lenvatinib Mesylate ndeye receptor tyrosine kinase (RTK) inhibitor ine selectivity yeVEGFR2.Iyo inoratidzira antineoplastic chiitiko, uye yakaratidzwa kurapwa kwevarwere vane munharaunda inodzokororwa kana metastatic, inofambira mberi, radioactive iodine (RAI) -refractory differentiated thyroid cancer.Lenvatinib Mesylate yakatanga kubvumidzwa neUS Food and Drug Administration (FDA) musi waKukadzi 13, 2015, ndokuzobvumidzwa nePharmaceuticals and Medical Devices Agency yeJapan (PMDA) musi waKurume 26, 2015, uye yakabvumidzwa neEuropean Medicine Agency (EMA) Chivabvu 28, 2015. Yakagadzirwa uye ikatengeswa seLenvima® naEisai.Lenvatinib Mesylate inonzi oral multiple receptor tyrosine kinase inhibitor ine yakasarudzika inosunga nzira inosarudzika inhibits kinase zviitiko zvevascular endothelial growth factor (VEGF) receptors, kuwedzera kune mamwe proangiogenic uye oncogenic nzira-inoenderana tyrosine kinases inofungidzirwa kuti inobatanidzwa mukupararira kwebundu. .Inoratidzirwa pakurapa kweinoenderera mberi radioiodine-refractory differentiated thyroid cancer.Lenvimainoshandiswa pachayo kurapa gomarara rethyroid rakasiyana (DTC), rudzi rwegomarara rerurindi risisagone kurapwa neradioactive iodine uye riri kufambira mberi.LENVIMA inoshandiswa pamwe nemumwe mushonga unonzi everolimus kurapa vanhu vakuru vane rudzi rwegomarara reitsvo rinonzi advanced renal cell carcinoma (RCC) mushure meimwe kosi yekurapwa nemumwe mushonga wekurwisa gomarara.