Lenvatinib Mesylate Yepakati CAS 15568-85-1 Kuchena > 97.0% (HPLC) Factory
Ruifu Chemical Supply Lenvatinib Mesylate Inopindirana Nekuchena Kwakanyanya
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Chemical Name | 5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione |
Mashoko anoreva zvakafanana | 5-(Methoxymethylene) Meldrum's Acid;Cabozantinib Kusachena 56;Lenvatinib Kusachena 79 |
Nhamba yeCAS | 15568-85-1 |
Nhamba yeCAT | RF-PI1967 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C8H10O5 |
Molecular Weight | 186.16 |
Melting Point | 132.0~134.0℃ |
Density | 1.297±0.06 g/cm3 |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Yellow Powder |
1 H NMR Spectrum | Zvinoenderana Nechimiro |
Kuchena / Analysis Method | >97.0% (HPLC) |
Zvose Zvisina Kuchena | <3.00% |
Test Standard | Enterprise Standard |
Usage | Pakati peLenvatinib Mesylate (CAS: 857890-39-2) |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione (CAS: 15568-85-1) iri pakati peLenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib imishonga yekenza yekenza yakagadzirwa neEisai Corporation yeJapan (Code: E7080), iri ye inhibitor ye oral multi-receptor tyrosine kinase (RTK) uye inogona kudzivisa kinase chiitiko chevascular endothelial growth factor (VEGF) Receptors VEGFR1 ( FLT1), VEGFR2 (KDR), uye VEGFR3 (FLT4).Lenvatinib inogonawo kudzivisa kubatanidzwa kwemamwe maRTK mu pathological angiogenesis, tumor kukura, uye kukura kwekenza kunze kwemaitiro avo emagetsi emagetsi anosanganisira fibroblast growth factor (FGF) receptors FGFR1, 2, 3, uye 4;platelet-derived growth factor receptor (PDGFR [alpha]), KIT, uye RET.[Zviratidzo]: Lenvatinib inokodzera kurapwa kwevarwere vekenza yethyroid yemunharaunda kudzoka kana metastasis rudzi, progressivity rudzi uye radioactive iodine-refractory differentiated type.Musi waKukadzi 13, 2015, US FDA yakabvumidza mushonga weanticancer Lenvatinib kurapa cancer yegomarara.Lenvatinib inonzi multi-target enzyme inhibitor, inokwanisa kuvharidzira VEGFR2 uye VEGFR3 (vascular endothelial growth factor receptor).Zita rekutengesa reLenvatinib ndiLenvima.Musi waChivabvu 20, 2015, European Medicines Agency (EMA) yakabvumidza Lenvatinib kurapwa kweanoparadza, munharaunda yepamusoro kana metastatic kusiyaniswa (papillary, follicular, Hurthle type) thyroid cancer (DTC).Mukutongwa, nguva yepakati yekupona kwevarwere veradioactive iodine-refractory DTC vakarapwa neLenvatinib yaive mwedzi gumi nemisere nepo kukosha kwevarwere vanotora placebo kuri mwedzi mitatu chete.