Lenvatinib Mesylate Yepakati CAS 15568-85-1 Kuchena > 97.0% (HPLC) Factory

Tsanangudzo Pfupi:

5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione

CAS: 15568-85-1

Kuchena:> 97.0% (HPLC)

Chitarisiko: Yellow Powder

Pakati peLenvatinib Mesylate CAS 857890-39-2

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Tsanangudzo:

Chemical Properties:

Chemical Name 5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione
Mashoko anoreva zvakafanana 5-(Methoxymethylene) Meldrum's Acid;Cabozantinib Kusachena 56;Lenvatinib Kusachena 79
Nhamba yeCAS 15568-85-1
Nhamba yeCAT RF-PI1967
Stock Status MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula C8H10O5
Molecular Weight 186.16
Melting Point 132.0~134.0℃
Density 1.297±0.06 g/cm3
Brand Ruifu Chemical

Zvinotsanangurwa:

Item Zvinotsanangurwa
Chitarisiko Yellow Powder
1 H NMR Spectrum Zvinoenderana Nechimiro
Kuchena / Analysis Method
>97.0% (HPLC)
Zvose Zvisina Kuchena <3.00%
Test Standard Enterprise Standard
Usage Pakati peLenvatinib Mesylate (CAS: 857890-39-2)

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

1

FAQ:

Application:

5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione (CAS: 15568-85-1) iri pakati peLenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib imishonga yekenza yekenza yakagadzirwa neEisai Corporation yeJapan (Code: E7080), iri ye inhibitor ye oral multi-receptor tyrosine kinase (RTK) uye inogona kudzivisa kinase chiitiko chevascular endothelial growth factor (VEGF) Receptors VEGFR1 ( FLT1), VEGFR2 (KDR), uye VEGFR3 (FLT4).Lenvatinib inogonawo kudzivisa kubatanidzwa kwemamwe maRTK mu pathological angiogenesis, tumor kukura, uye kukura kwekenza kunze kwemaitiro avo emagetsi emagetsi anosanganisira fibroblast growth factor (FGF) receptors FGFR1, 2, 3, uye 4;platelet-derived growth factor receptor (PDGFR [alpha]), KIT, uye RET.[Zviratidzo]: Lenvatinib inokodzera kurapwa kwevarwere vekenza yethyroid yemunharaunda kudzoka kana metastasis rudzi, progressivity rudzi uye radioactive iodine-refractory differentiated type.Musi waKukadzi 13, 2015, US FDA yakabvumidza mushonga weanticancer Lenvatinib kurapa cancer yegomarara.Lenvatinib inonzi multi-target enzyme inhibitor, inokwanisa kuvharidzira VEGFR2 uye VEGFR3 (vascular endothelial growth factor receptor).Zita rekutengesa reLenvatinib ndiLenvima.Musi waChivabvu 20, 2015, European Medicines Agency (EMA) yakabvumidza Lenvatinib kurapwa kweanoparadza, munharaunda yepamusoro kana metastatic kusiyaniswa (papillary, follicular, Hurthle type) thyroid cancer (DTC).Mukutongwa, nguva yepakati yekupona kwevarwere veradioactive iodine-refractory DTC vakarapwa neLenvatinib yaive mwedzi gumi nemisere nepo kukosha kwevarwere vanotora placebo kuri mwedzi mitatu chete.

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