Letrozole CAS 112809-51-5 API Factory Aromatase Inhibitor II High Quality
Supply with High Purity and Stable Quality
Zita reKemikari: Letrozole
CAS: 112809-51-5
Aromatase Inhibitor II
API High Quality, Commercial Production
| Chemical Name | Letrozole |
| Mashoko anoreva zvakafanana | CGS-20267;Femara |
| Nhamba yeCAS | 112809-51-5 |
| Nhamba yeCAT | RF-API86 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
| Molecular Formula | C17H11N5 |
| Molecular Weight | 285.3 |
| Melting Point | 181.0 kusvika 183.0 ℃ |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kusvika kuOff-White Crystalline Powder |
| Solubility | Yakasununguka Soluble muDichloromethane, Zvishoma Soluble muEthanol uye Practically Insoluble muMvura |
| Kuzivikanwa IR | Spectrum yemuenzaniso inoenderana neyereferensi mwero |
| Kuzivikanwa HPLC | Nguva yekuchengeta yemuenzaniso webvunzo inoenderana neiyo yereferensi mwero |
| Mvura Yemukati (neKF) | ≤0.30% |
| Residue paIgnition | ≤0.10% |
| Related Substances | |
| Zvinhu zvinoenderana A | ≤0.30% |
| Zvinhu zvinoenderana B | ≤0.20% |
| Chero Kusachena Kusina Kutaurwa | ≤0.10% |
| Zvose Zvisina Kutaurwa Netsvina | ≤0.30% |
| Zvose Zvisina Kuchena | ≤0.50% |
| Residual Solvents | |
| Ethyl Acetate | ≤0.50% |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| DMF | ≤0.088% |
| Heavy Metals | ≤10ppm |
| Assay | 98.0% ~ 102.0% (pane anhydrous basis) |
| Sherufu Hupenyu | 24 Mwedzi |
| Test Standard | Enterprise Standard |
| Usage | API, Aromatase Inhibitor II |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Letrozole (CAS 112809-51-5) chikamu chechizvarwa chitsva che aromatase inhibitors anonyanya kusarudzwa uye inogadzirwa nemaitiro ebenzotriazole derivative.Letrozole inhibits aromatase kudzikisa estrogen mazinga, nokudaro kudzivirira estrogen kubva mukukurudzira bundu kukura.Yayo mu vivo chiitiko ndeye 150-250 nguva yakasimba kupfuura yechizvarwa chekutanga aromatase inhibitor Amarante.Sezvo yakanyanya kusarudzwa, haizokanganisa glucocorticoid, mineralocorticoid uye thyroid mabasa;kunyangwe pamadosi akakwirira, haizove nechero inhibiting mhedzisiro pane adrenal corticosteroid secretion, ichipa iyo yakanyanya kurapwa index.Letrozole haina huturu hwehupfu kune chero masystem emuviri uye nhengo dzinotariswa, haina mutagenicity uye carcinogenic mhedzisiro, ine zvishoma muchetura mhedzisiro, inoshivirirwa zvakanaka, uye ine yakasimba anticancer mhedzisiro kupfuura mamwe aromatase inhibitors uye antiestrogen zvinodhaka.Letrozole inokodzera varwere vekenza yemazamu postmenopausal avo vasina kupindura estrogen-kudzvinyirira kurapwa uye nekutanga kenza yemazamu kurapwa.Inoshandiswa kurapa varwere vane postmenopausal vane gomarara rezamu repamusoro uye inoshanda senzira yechipiri yekutevera kurapwa isina kubudirira antiestrogen.
