Luliconazole CAS 187164-19-8 Purity ≥99.0% HPLC Factory API High Quality
Supply Luliconazole uye Related Intermediates
Luliconazole CAS 187164-19-8
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| Chemical Name | Luliconazole |
| Mashoko anoreva zvakafanana | (2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile;NND 502 |
| Nhamba yeCAS | 187164-19-8 |
| Nhamba yeCAT | RF-API110 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C14H9Cl2N3S2 |
| Molecular Weight | 354.27 |
| Melting Point | 150.0 kusvika 154.0 ℃ |
| Kutenderera kwakananga [a]20/D | -48.0° kusvika -53.0° (C=1, DMF) |
| Solubility | Insoluble muMvura;Soluble muacetone;Zvishoma Soluble muMethanol |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Kunze-Kuchena kusvika kuChiedza Yero yeCrystalline Powder |
| Kuzivikanwa IR | Iyo infrared spectrum yemuenzaniso inofanira kuenderana neiyo yereferensi mwero |
| Kuzivikanwa HPLC | Nguva yekuchengeta yenhongonya huru yemuenzaniso mhinduro inofanirwa kuenderana neiyo yeyakajairwa mhinduro sezvakawanikwa muyedzo |
| Kurasika paKuomesa | ≤0.50% |
| Residue paIgnition | ≤0.20% |
| Masimbi anorema (Pb) | ≤20ppm |
| Related Substances | |
| Chero Kusachena Kwemunhu | ≤0.20% |
| Zvose Zvisina Kuchena | ≤0.50% |
| Residual Solvents | |
| Methanol | ≤3000ppm |
| Acetonitrile | ≤410ppm |
| Dichloromethane | ≤600ppm |
| N-Hexane | ≤290ppm |
| Ethyl Acetate | ≤5000ppm |
| Tetrahydrofuran | ≤720ppm |
| Methyl tert-Butyl Ether | ≤5000ppm |
| N-Heptane | ≤5000ppm |
| Triethylamine | ≤320ppm |
| Dimethyl Sulfoxide | ≤5000ppm |
| Kuchena / Analysis Method | ≥99.0% (HPLC) (pane yakaomeswa) |
| Test Standard | Enterprise Standard |
| Usage | Pharmaceutical Intermediates |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro.
Luliconazole (CAS: 187164-19-8) is topical antifungal imidazole antibiotic ine yakakura-spectrum uye ine simba antifungal chiitiko.Luliconazole imhando yeanalogue ye lanoconazole.Inogona kukanganisa fungal cell wall synthesis uye fungal kukura nekudzikira mazinga eergosterol kuburikidza nekudzivisa lanosterol demethylase chiitiko.Kunze kwekushandiswa kurapa tsoka yemutambi, jock itch uye ringworm, yakagadziridzwawo kurapwa kwe onychomycosis (nail fungus) uye yapindawo muchikamu chekiriniki III.Ichi chigadzirwa chakatanga kugadzirwa neJapan pesticide Corporation (NihonNohyaku Co., Ltd.).Muna Mbudzi 2013, iyo FDA yakabvumidza 1% luliconazole cream yekupinda mumusika kurapwa kwepamusoro-soro yetsoka yemumhanyi, jock itch uye ringworm ine zita rekutengesa reLuzu uye yakatanga kupinda mumusika kuNorth America.Kubva muna Kubvumbi 2005, luliconazole yakanga yatenderwa kupinda mumusika muJapan pasi pezita rekutengesa reLulicon.Muna Ndira 2010 naChikumi 2012, yakatenderwa kushambadzira muIndia neChina, zvichiteerana.
