Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8 PF-07321332 Boceprevir Pakati
Commercial Supply PF-07321332 Paxlovid Inoenderana Nepakati Nemhando yepamusoro
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Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8
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Chemical Name | Methyl (S) -2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate |
Mashoko anoreva zvakafanana | Methyl (S) -2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate;(αS,3S) -α--[(tert-Butyloxycarbonyl)aMino]-2-oxo-3-pyrrolidinepropanoic acid Methyl Ester;(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate |
Nhamba yeCAS | 328086-60-8 |
Nhamba yeCAT | RF-PI317 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
Molecular Formula | C13H22N2O5 |
Molecular Weight | 286.33 |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika kuOff-White Powder |
Identification A | IR: Yakafanana neReference Substance |
Kuzivikanwa B | Nguva Yekuchengeta: Yakafanana neReference Substance |
Kurasika paKuomesa | ≤1.0% |
Residue paIgnition | ≤0.20% |
Kusachena Kumwechete | ≤0.50% |
Zvose Zvisina Kuchena | ≤2.0% |
Masimbi anorema (Pb) | ≤20ppm |
Kuchena | ≥98.0% |
Test Standard | Enterprise Standard |
Usage | Pakati pePF-07321332 Paxlovid (CAS 2628280-40-8) uye Boceprevir (CAS 394730-60-0) |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Methyl (S) -2- (Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate (CAS 328086-60-8) iri pakati pePF-07321332 Paxlovid (CAS 2628280-40 -8) uye Boceprevir (CAS 394730-60-0).PF-07321332, chikamu chakakosha chePaxlovid (PF-07321332 uye Ritonavir) inova yekuongorora COVID-19 yemuromo antiviral mumiriri, ndeye nemuromo bioavailable 3C-senge protease (3CLPRO) inhibitor ine simba antiviral mhedzisiro kurwisa hutachiona hweSARS-CoV-2. uye COVID-19.Musi waNove 6, 2021, Pfizer akazivisa kuti Paxlovid akadzikisa zvakanyanya kuchipatara uye kufa, zvichibva pakuongororwa kwechinguvana kwechikamu chechipiri chechikamu chechipiri EPIC-HR (Kuongorora kweProtease Inhibition yeCOVID-19 muVarwere Vepamusoro-soro) yevarwere vakura vasiri muchipatara vane COVID-19, vari panjodzi huru yekuenderera mberi nehurwere hwakanyanya.Boceprevir (EBP-520) iHCV protease inhibitor (Ki = 14 nM) yekurapa hutachiona hwehepatitis C.Boceprevir ine pegylated interferon uye ribavirin (PegIFN/RBV) yakagonesa kuvandudzwa mukuchengetedzwa kwehutachiona hwehutachiona hwevarwere vane genotype 1 HCV.Boceprevir inosangana ne immunosuppressive therapy (IT) nekudzivisa cytochrome P450 3A enzyme.