Molnupiravir (EIDD-2801) CAS 2349386-89-4 COVID-19 API High Quality
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Molnupiravir (EIDD-2801) CAS 2349386-89-4
| Chemical Name | Molnupiravir (EIDD-2801) |
| Mashoko anoreva zvakafanana | MK-4482;β-D-N4-Hydroxycytidine-5′-isopropyl ester;((2R,3S,4R,5R)-3,4-dihydroxy-5-((E)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2 -yl) methyl isobutyrate |
| Nhamba yeCAS | 2349386-89-4 |
| Nhamba yeCAT | RF-API97 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
| Molecular Formula | C13H19N3O7 |
| Molecular Weight | 329.31 |
| Solubility | Soluble muDMSO |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kusvika kuOff-White Powder |
| Kuzivikanwa IR | Sample Spectrum inoenderana neiyo yereferenzi standard |
| Kuzivikanwa HPLC | Nguva yekuchengetwa kwepamusoro pepamusoro pemhinduro yemuenzaniso inoenderana neiyo yemhinduro yakajairwa |
| Related Substances | |
| Kusachena A | ≤0.15% |
| Kusachena B | ≤0.15% |
| Chero Kusachena Kusina Kutaurwa | ≤0.15% |
| Zvose Zvisina Kutaurwa Netsvina | ≤0.30% |
| Zvose Zvisina Kuchena | ≤0.50% |
| Residual Solvents | |
| N-Heptane | ≤5000ppm |
| Ethanol | ≤5000ppm |
| Isopropyl Acetate | ≤5000ppm |
| Acetonitrile | ≤410ppm |
| Methylene Dichloride | ≤600ppm |
| Acetone | ≤5000ppm |
| Isopropanol | ≤5000ppm |
| Zvemumvura (KF) | ≤0.50% |
| Residue paIgnition | ≤0.10% |
| Optical Rotation | -7.5° kusvika -9.5° (C=0.5, Methanol) |
| Heavy Metals | ≤10ppm |
| Kuchena / Analysis Method | ≥99.5% (230nm) |
| Assay / Analysis Method | 98.0% ~ 102.0% (HPLC pane yakaomeswa) |
| Sherufu Hupenyu | 24 Mwedzi |
| Test Standard | Enterprise Standard |
| Usage | API, Molnupiravir (EIDD-2801) COVID-19 Inhibitor |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Molnupiravir (EIDD-2801, MK-4482) is an orally bioavailable prodrug of the ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) ine wide-spectrum antiviral chiitiko kurwisa SARS-CoV-2, MERS-CoV, SARS-CoV, uye iyo inokonzeresa mumiriri weCOVID-19.Molnupiravir inotengeswa pasi pezita remhando yeLagevrio uye kazhinji se emorivir.Molnupiravir yakaratidzwa kuvandudza kushanda kwepulmonary, kuderedza uremu hwemuviri uye kuderedza huwandu hwehutachiona mumapapu.Pamusoro pekuita kurwisa coronavirus, Molnupiravir, muzvidzidzo zvemurabhoritari, yakaratidza chiitiko chinopesana nemwaka uye furuwenza yeshiri, kufema syncytial virus, chikungunya virus, Ebola virus, Venezuelan equine encephalitis virus, uye Eastern equine encephalitis virus.Molnupiravir yakatanga kugadzirwa kuti irape furuwenza kuEmory University nekambani yeyunivhesiti iyi inogadzira mishonga, Drug Innovation Ventures kuEmory (DRIVE), asi inonzi yakasiiwa nekuda kwekunetsekana nekusagadzikana.Yakazotorwa nekambani yeMiami-based Ridgeback Biotherapeutics, iyo yakazobatana neMerck & Co kugadzira mushonga uyu zvakare.Molnupiravir yakatenderwa kushandiswa mukurapa muUnited Kingdom muna Mbudzi 2021.
