N-Acetyl-L-Cysteine CAS 616-91-1 (Ac-Cys-OH; NAC) Chiyero 98.5~101.0% Factory High Quality
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weN-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) ine mhando yepamusoro.Ruifu Chemical inopa akateedzana amino acids uye zvinobva.Nekuda kwemhando yezvigadzirwa zvedu zvemhando yepamusoro, mitengo inonzwisisika, takawana mukurumbira wakanaka pamwe nekuvimba nevatengi vedu vekumba nekune dzimwe nyika.Isu tinogona kupa COA, kuendesa pasi rese, zvidiki uye huwandu hwakawanda huripo.Kana iwe uchifarira N-Acetyl-L-Cysteine,Please contact: alvin@ruifuchem.com
Chemical Name | N-Acetyl-L-Cysteine |
Mashoko anoreva zvakafanana | Ac-Cys-OH;Acetylcysteine;NAC;LNAC;N-Acetylcysteine;N-Acetyl-3-Mercaptoalanine;Acetyl-Laevo-Cysteine |
Stock Status | MuStock, Kukwanisa Kugadzira Matani makumi mashanu pamwedzi |
Nhamba yeCAS | 616-91-1 |
Molecular Formula | C5H9NO3S |
Molecular Weight | 163.19 |
Melting Point | 106.0~108.0℃(lit.) |
Sensitive | Air Sensitive |
Mvura Solubility | Soluble muMvura, Anenge Transparency |
Solubility | Soluble muEthanol, Methanol, Doro.Inenge isinganyungudike muEther |
Storage Temp. | Yakavharwa muKuoma, Chengetedza paChikamu Tembiricha |
COA & MSDS | Available |
Classification | Amino Acids & Derivatives |
Brand | Ruifu Chemical |
Risk Statements | 36/37/38 - Kushungurudza maziso, kufema system uye ganda. |
Safety Statements | S22 - Usafeme guruva.S24/25 - Dzivisa kusangana neganda nemeso. |
WGK Germany | 3 |
RTECS | HA1660000 |
F | 10-23 |
TSCA | Ehe |
HS Code | 2922491990 |
Items | Kuongorora Maitiro | Results |
Chitarisiko | White Crystals kana Crystalline Powder;Yakasimba Acid Kuravira | Conforms |
Identification | Infrared Absorption Spectrum | Conforms |
Kutenderera kwakananga [α]20/D | +21.3° kusvika +27.0° (C=5 muPhosphate Buffered Saline) | +23.5° |
State of Solution (Transmittance) | Zvakajeka uye Zvisina Ruvara ≥98.0% | 99.0% |
Chloride (Cl) | ≤0.040% | <0.040% |
Sulfate (SO4) | ≤0.030% | <0.030% |
Ammonium (NH4) | ≤0.020% | <0.020% |
Simbi (Fe) | ≤20ppm | <20ppm |
Masimbi anorema (Pb) | ≤10ppm | <10ppm |
Zinc (Zn) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤1.0ppm | <1.0ppm |
Related Substances | (HPLC Nzira) | |
L-cystine | ≤0.50% | Conforms |
L-Cysteine | ≤0.50% | Conforms |
N,N'-Diacetyl-L-Cystine | ≤0.50% | Conforms |
N,S-Diacetyl-L-Cysteine | ≤0.50% | Conforms |
Mumwe nomumwe Kusachena | ≤0.50% | Conforms |
Zvose Zvisina Kuchena | ≤0.50% | Conforms |
Kurasika paKuomesa | ≤0.50% | 0.20% |
Residue paIgnition (Sulfated) | ≤0.20% | 0.05% |
Assay | 98.5 kusvika 101.0% (paDried Basis) | 99.90% |
pH Kukosha | 2.0 kusvika 2.8 (1.0g mu100ml yeH2O) | 2.5 |
Biochemical Toxicity | Passes | Passes |
Volatile Organic Substances | Pass | Pass |
Endonuclease Detection | ≤0.1 EU/g | <0.1 EU/g |
Mhedziso | Ichi Chigadzirwa neKuongorora Zvibvumirano neiyo Standard yeAJI97 | |
Main Use | Amino Acids;Zvokudya zvinowedzera;Pharmaceutical Intermediates |
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) AJI97 Test Method
N-Acetyl-L-Cysteine, kana yakaomeswa, ine kwete pasi pe98.5 muzana uye kwete kupfuura 101.0 muzana yeN-Acetyl-L-Cysteine (C5H9NO3S).
Tsanangudzo: Makristasi machena kana crystalline poda, yakasimba acid kuravira.
Inonyungudika zvakasununguka mumvura, inonyungudika mu ethanol, isinganyungudika mu ether.
Solubility (H2O, g/100g): 17 (20℃), 80 (40℃), 260 (60℃)
Kuzivikanwa: Enzanisa infrared absorption spectrum yemuenzaniso neiyo yechiyero ne potassium bromide disc nzira.
Kutenderera kwakananga [α]20/D: Sample yakaomeswa, C=8, phosphate buffer solution
State of Solution (Transmittance): 0.5g mu10ml yeH2O, spectrophotometer, 430nm, 10mm sero ukobvu.
Heavy Metals (Pb): 2.0g, (1), ref: 2.0ml yePb Std.(0.01mg/ml)
Zinc (Zn): Atomic absorption nzira
Zvinoenderana Zvinhu: HPLC nzira
Kurasikirwa Pakuomesa: Muvacuum, pa70 ℃ kwemaawa mana
Residue paIgnition (Sulfated): AJI Muedzo 13
Chiyero: Muenzaniso wakaomeswa, 200mg, 0.05mol/L I2 1ml = 16.320mg C5H9NO3S
pH: 1.0g mu100ml yeH2O
Inokurudzirwa kuchengetedza muganho uye mamiriro: Yakachengetedzwa midziyo yakasimba painodzorwa tembiricha yekamuri (1 makore).
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) USP35 Test Method
DEFINITION
Acetylcysteine ine NLT 98.0% uye NMT 102.0% yeL-threonine (C5H9NO3S), yakaverengerwa pane yakaomeswa.
KUZIVA
A. INFRARED AVORPTION <197K>
ASSAY
PROCEDURE
Nharembozha: 6.8 g/L ye monobasic potassium phosphate.Gadzirisa nephosphoric acid kusvika pH ye3.0.
Sodium metabisulfite mhinduro: 0.5 mg / mL ye sodium metabisulfite mumvura, ichangobva kugadzirirwa
Yemukati chiyero mhinduro: 5 mg/mL yeUSP L-Phenylalanine RS muSodium metabisulfite mhinduro
Yakajairika stock solution: 10 mg/mL yeUSP Acetylcysteine RS muSodium metabisulfite mhinduro
Mushonga wakajairika: 0.5 mg/mL yeUSP Acetylcysteine RS uye 0.25 mg/mL yeUSP L-Phenylalanine RS muSodium metabisulfite mhinduro kubva kuStandard stock solution uye Internal standard solution
Sample stock solution: 10 mg/mL yeAcetylcysteine muSodium metabisulfite mhinduro
Sample solution: 0.5 mg/mL yeAcetylcysteine uye 0.25mg/mL yeUSP L-Phenylalanine RS muSodium metabisulfite solution kubva kuSample stock solution uye Internal standard solution
Chromatographic system
(Ona Chromatography <621>, System Suitability.)
Modhi: LC
Detector: UV 214 nm
Column: 3.9-mm × 30-cm;kurongedza L1
Kuyerera kweyero: 1.5 mL/min
Jekiseni saizi: 5 µL
Kukodzera kwehurongwa
[Cherechedza-Nguva dzekuchengeta acetylcysteine neL-phenylalanine dzinenge 0.5 uye 1.0, zvichiteerana.]
Kukodzera zvinodiwa
Chisarudzo: NLT 6 pakati peacetylcysteine uye L-phenylalanine
Kutsauswa muyero: NMT 2.0%
Analysis
Samples: Yakajairwa mhinduro uye Sample mhinduro
Verenga chikamu cheacetylcysteine (C5H9NO3S) muchikamu cheAcetylcysteine yakatorwa:
Mhedzisiro = (RU/RS) × (CS/CU) × 100
RU = peak mhinduro chiyero cheacetylcysteine kuL-phenylalanine kubva kuSample solution
RS = peak response ratio yeacetylcysteine ku-L-phenylalanine kubva kuStandard solution
CS = kusungwa kweUSP Acetylcysteine RS muStandard solution (mg/mL)
CU = kusanganiswa kweacetylcysteine mumhinduro yeSample (mg/mL)
Maitiro ekugamuchira: 98.0% -102.0% pane yakaomeswa hwaro
KUSIRIRA
ZVINOSARA PAZVINOBATIDZA <281>: NMT 0.5%
ZVINORERA METALS, Nzira II <231>
[KUCHENJERA-Ita nehanya nekuti kuputika kunogona kuitika.]
Ongororo: Nenzira inodonha, nyorovesa sampuli ne 2 mL ye nitric acid, uye enderera sezvakarairwa kugadzirira Muedzo.
Maitiro ekugamuchira: NMT 10 ppm
ZVIYEDZO ZVAKANAKA
OPTICAL kutenderera, Chaiyo Rotation <781S>
Buffer: Sanganisa 29.5 mL ye1 N sodium hydroxide, 50 mL ye1 M monobasic potassium phosphate, uye mvura yakakwana kuita zana remL.Rongedza kune pH ye7.0 ± 0.1 nekuwedzera imwe mhinduro, sezvinodiwa.
Sample solution: Mu 25-mL volumetric flask, sanganisa 1.25 g ne 1 mL ye edetate disodium solution (1 mu 100), wedzera 7.5mL yesodium hydroxide solution (1 mu25), wosanganisa kuti inopera.Dilute neBuffer kusvika kuvhoriyamu.
Maitiro ekugamuchira: +21 ° kusvika +27 °
pH <791>: 2.0-2.8 mune mhinduro (1 mu100)
KURASUKA PAKUOMESA <731>: Pukuta sampuli pakumanikidzwa kwe50 mm ye mer cury pa 70 ° kwe4 h: inorasikirwa neNMT 1.0% yehuremu hwayo.
ZVIMWE ZVINODIWA
PACKAGE AND STORAGE: Chengetedza mumidziyo yakaoma, uye chengeta patembiricha yekamuri inodzorwa.
USP REFERENCE MITIRO <11>
USP Acetylcysteine RS
USP L-Phenylalanine RS
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
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HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
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Basa & Kushandiswa kweN-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) powder
1. N-Acetyl-L-Cysteine, inozivikanwawo seN-Acetylcysteine kana Acetylcysteine (NAC), mushonga wemishonga uye kudya kunovaka muviri kunoshandiswa kunyanya semucolytic agent uye mukutarisira kweparacetamol (acetaminophen) kudarika.Mamwe mashandisirwo anosanganisira sulfate repletion mumamiriro ezvinhu, senge autism, uko cysteine uye zvinoenderana nesarufa amino acids zvinogona kupera.
2. N-Acetyl-L-Cysteine inobva ku cysteine apo boka reacetyl rinosungirirwa paatomu yenitrogen.Mushonga uyu unotengeswa sechikafu chekuwedzera chinowanzo daidza antioxidant uye chiropa kuchengetedza mhedzisiro.Inoshandiswa semushonga wechikosoro nekuti inotyora zvisungo zve disulfide mumukasi uye inonyorovesa, zvichiita kuti zvive nyore kukosora.Icho zvakare ichi chiito chekutyora disulfide zvisungo zvinoita kuti zvive zvakakosha mukuonda zvisina kujairika gobvu mucus mune cystic uye pulmonary fibrosis varwere.
3. Acetylcysteine is a mucolytic agent ine simba mucolytic effect.Iro sulfhydryl boka riri mumorekuru rinogona kutyora disulfide bond mu glycoprotein polypeptide cheni musputum, nokudaro kuderedza viscosity ye sputum, uye kuita sputum mvura uye nyore kukosora.Ichi chigadzirwa chinogonawo kuputsa DNA fibers mu purulent sputum, saka haigoni kungopedza sputum yakachena inonamira, asiwo purulent sputum.Kune varwere vane general expectorants isingashande, chigadzirwa ichi chinogona kuramba chichishanda.
4. Inoshandiswa semushonga wekunyungudutsa phlegm.Inoshandiswa mukutsvagisa biochemical uye mushonga senge antidote yephlegm uye acetaminophen chepfu.Biochemical reagent, mushonga, chigadzirwa ichi chinoshandiswa se expectorant, akati phlegm iri nyore kuchenesa.
5. Zvinowanzoitika zvinosanganisira kusvotwa uye kurutsa kana uchinge watorwa nemuromo.Ganda rinogona kutsvuka nekukwenya chero nguva.A non-immune type yeanaphylaxis inogonawo kuitika.Zvinoita kunge zvakachengeteka pamuviri.Kune paracetamol overdose, inoshanda nekuwedzera mwero we glutathione, antioxidant iyo inogona kudzikamisa muchetura kuputswa zvigadzirwa zveparacetamol.Kana ikafemerwa, inoita semucolytic nekuderedza ukobvu hwemachu.
6. Acetylcysteine yakatanga kushandiswa muna 1960 uye yakatanga kushandiswa mune zvekurapa muna 1968. Iri paWorld Health Organization's List of Essential Medicines, iyo inonyora mishonga yakachengeteka uye inoshanda zvikuru inodiwa muhutano hwehutano.Inowanikwa semushonga wegeneric uye haidhure.
7. N-Acetyl-L-Cysteine ndiyo acetylated fomu yeL-cysteine iyo inonyanya kushandiswa uye inoshandiswa.Iyo zvakare antioxidant inobatsira kurwisa mavhairasi.N-Acetyl-l-Cysteine yakashandiswa sekudzivirira chiropa uye kuputsa pulmonary uye bronchial mucus.
8. N-Acetyl-L-Cysteine inogona kuwedzera glutathione mazinga mumasero.
9. N-Acetyl-L-Cysteine iamino acid yakakosha, imwe chete yetatu chete ine sarufa-ine amino acids, mamwe ari taurine (iyo inogona kugadzirwa kubva kuL-cysteine) uye L-methionine iyo L-cysteine inogoneka. kugadzirwa mumuviri nematanho akawanda.
10. N-Acetyl-L-Cysteine inogona kuita se antioxidant, inogona kudzivirira zvirwere zvechiropa, uye inogona kubatsira kuomesa madhayamita ega ebvudzi riripo kana yakatorwa nguva dzose.
11. Kushandiswa muminda yezvokurapa Sezvo Respiratory system agent, inogona kushandiswa semushonga wekunyungudutsa madhiramu ephlegm.inogona kurapa bronchitis.uyezve, N-Acetyl-L-Cysteine inogona kushandiswa semushonga apo acetaminophen chepfu.
12. Kushandiswa muminda yecosmetic N-Acetyl-L-Cysteine ine simba guru mukubvisa okisijeni isina radicals nemamwe maokisi uye kunonotsa kuchembera, inogonawo kukanganisa kugadzirwa kwe melanin, uye inobatsira kubvisa freckle paganda.
13. Kushandiswa mukudya kwemhuka N-Acetyl-L-Cysteine inogona kushandiswa sekuwedzera kwekudya.
14. Cosmetics inonyanya kushandiswa kwerunako mvura, perm fluid, sun-proof skin care cream.Iine basa rekudzivirira kuchembera kwebiological.N-Acetyl-l-Cysteine inogona kudzivirira nekurapa kukuvara kwemwaranzi.N-acetyl Cysteine inogona kubvisa ganda melanin pachayo, kushandura chimiro cheganda pachayo, ganda rinova chena chena.Iri rudzi rwezvakanakira chena zvizoro.
15. Chikafu chekuwedzera.Inoshandiswa muchingwa, kukurudzira kuumbwa kwe gluten uye kukurudzira kuvirisa, mold, kudzivirira kukwegura.Inoshandiswa mumajusi echisikigo kudzivirira vhitamini C kubva kune oxidizing uye kudzivirira majusi kubva kushanduka shava.
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