N-Hydroxysuccinimide (HOSu) CAS 6066-82-6 Coupling Reagent Purity >99.0% (HPLC)

Tsanangudzo Pfupi

Kemikari Zita: N-Hydroxysuccinimide

Anoreva zvakafanana: HOSu;NHS

CAS: 6066-82-6

Kuchena:> 99.0% (HPLC)

Kuonekwa: White Crystalline Powder

Coupling Reagent yePeptide, Yemhando yepamusoro

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri weN-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6) ine mhando yepamusoro.Ruifu Chemical inopa akateedzana ekudzivirira reagents uye coupling reagents.Ruifu inogona kupa kutumirwa kwepasirese, mutengo wemakwikwi, madiki uye akawanda akawanda aripo.Tenga N-Hydroxysuccinimide,Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	N-Hydroxysuccinimide
Mashoko anoreva zvakafanana	HOSu;NHS;1-Hydroxysuccinimide;1-Hydroxy-2,5-Pyrrolidinedione;N-Hydroxy-2,5-dioxopyrrolidine
Stock Status	MuStock, Mass Production
Nhamba yeCAS	6066-82-6
Molecular Formula	C4H5NO3
Molecular Weight	115.09 g/mol
Melting Point	93.0~98.0℃(lit.)
Density	1.649
Sensitive	Hygroscopic.Heat Sensitive, Kunyorova Kunzwa
Solubility muDioxane	Soluble in Dioxane, Anenge Transparency
Solubility mumvura	Soluble mumvura
Storage Temp.	Nzvimbo Inotonhorera & Yakaoma (2~8℃)
COA & MSDS	Available
Category	Coupling Reagents
Brand	Ruifu Chemical

Zvinotsanangurwa:

Items	Kuongorora Maitiro	Results
Chitarisiko	White Crystalline Powder	Zvinoenderana
Melting Point	93.0~98.0℃	94.0~97.0℃
Kurasika paKuomesa	<0.50%	0.15%
Kuchena / Analysis Method	>99.0% (HPLC)	99.5%
Infrared Spectrum	Inopindirana neChimiro	Zvinoenderana
Proton NMR Spectrum	Inopindirana neChimiro	Zvinoenderana
Mhedziso	Chigadzirwa chacho chakaedzwa uye chinoenderana nezvinodiwa

Test Method:

Nharembozha chikamu: 0.1% phosphoric acid mhinduro: acetonitrile =90:10
Wavelength: 220nm
Kuyerera kweyero: 1ml/min

Pakeji/Kuchengeta/Shipping:

Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Kunyorova.Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma (2~8℃) yekuchengetera kure nezvinhu zvisingaenderane.Dzivirira kubva kuchiedza uye unyoro.
KutumiraKuendesa kupasirese neFedEx / DHL Express.Ipa kutumirwa nekukurumidza uye kwakavimbika.

Zvakanakira:

Yakakwana Capacity: Inokwana zvivakwa uye matekiniki

Professional Service: Imwe inomira kutenga sevhisi

OEM Package: Tsika pasuru uye label iripo

Fast Delivery: Kana iri mukati me stock, mazuva matatu ekutumira anovimbiswa

Yakagadzika Supply: Chengetedza zvine musoro stock

Tsigiro yehunyanzvi: Tekinoroji mhinduro iripo

Tsika Synthesis Service: Kubva pamagiramu kusvika makirogiramu

Hunhu Hwepamusoro: Yakagadzira yakakwana yemhando yekusimbisa system

FAQ:

Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.

Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.

Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.

HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.

Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.

Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.

MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.

Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.

Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.

Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.

Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.

Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.

6066-82-6 - Njodzi uye Kuchengeteka:

Hazard Symbols Xi - Irritant
Risk Codes
36/37/38 - Kushungurudza maziso, kufema system uye ganda.
Tsanangudzo Yekuchengetedza
S22 - Usafeme guruva.
S24/25 - Dzivisa kusangana neganda nemeso.
S26 - Kana wasangana nemaziso, simbura nekukasira nemvura yakawanda uye tsvaga mazano ekurapwa.
S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera.
WGK Germany 3
TSCA Hongu
HS Code 2925190090
Hazard Note Irritant

Application:

N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6), reagent yekugadzirira ester inoshanda yeamino acids.Peptide solid phase synthesis linking agent.
N-Hydroxysuccinimide inowanzoshandiswa kubatsira carbodiimide-mediated peptide coupling kuburikidza nekugadzira ester inoshanda yepakati kuburikidza ne condensation yepamusoro carboxyl boka uye NHS.Iyo NHS-reactive ester yepakati inotapukirwa nekurwiswa kwenucleophilic nema primary amines uye inoguma nekuumbwa kweamide bonds yakagadzikana pakati peiyo biomaterial surface uye N-terminus yepeptide.
N-Hydroxysuccinimide is hydroxylated succinimide inoshandiswa zvakanyanya mukushandiswa kwecarboxylic acids kuNHS-esters kukurudzira kubatana nemanucleophiles.Iyi nzira inonyanya kushandiswa mukumisikidza emahara asidhi mafomu efluorophores ekusimudzira kusangana kweiyi fluorophores kune amine masara emapuroteni.Kushandiswa kweNHS ester activation yakatsanangurwa zvakare mukubatanidzwa kweN-acyl amino acids.
Inoshandiswa pakugadzirwa kweamino acid inodzivirira, semi-synthetic kanamycin uye pharmaceutical intermediates.N-hydroxybutyldiimide uye zvigadzirwa zvayo zvakakosha zvakagadziriswa zvekugadzirwa kwepeptides, antibiotics, amino acids uye mapuroteni.N-hydroxybutyldiimide inoshandiswa mukugadzirira kushanda. esters, uye kuvharirwa kweiyo optically inoshanda mhedzisiro yekubatanidza peptide ine huwandu hwakasiyana hweUSES mukurapa, uye zvakare iri yakakosha kemikari raw material.
N-Hydroxysuccinimide inoshandiswa pakuvandudza amidations munzira ye carbodiimide.Inoshandiswawo kumisa boka recarboxyl uye rinosangana neamine kugadzira amide.Inobatanidzwa mukugadzirira kweN-hydroxymaleimide-styrene copolymer.

Nzira yekugadzira:

N-Hydroxysuccinimide yakagadzirirwa sezvinotevera: 100g (1.0mol) succinic anhydride uye 70g (1.0mol) yehydroxylamine hydrochloride inopisa pamwe chete, maitiro ekugadzirisa anochengetwa pasi pekumanikidzwa kwakashata kuti abvise mavhiri anogadzirwa, uye anokurumidza kupisa kusvika pamusoro pe125 ℃ , yozosimuka zvishoma nezvishoma kusvika 160℃ mushure me1H.Kudziya kwakamiswa uye tembiricha payakadonha kusvika 125 ℃, iyo yemvura reaction yakadirwa mukati mediethyl ether uye yakamutswa zvine simba.Mushure mekunge chigadzirwa charapwa, iyo ether layer yakabviswa, chigadzirwa chakaporeswa chakapisa kusvika pakuvira ne400ml yebutanol, inopisa yakasefa, uye filtrate yakakurumidza kutonhora kusvika ku0 ℃.Mushure mekusefa kwe1H, makristasi akagezwa zvakatevedzana nebutanol uye diethyl ether, uye yakawanikwa isina kuchena chigadzirwa yakadzokororwa kubva ethyl acetate kuti iwane 50g yechigadzirwa chakapedzwa mugoho re44%.