Olmesartan Medoxomil CAS 144689-63-4 Kuchena > 99.5% (HPLC) API Factory

Tsanangudzo Pfupi

Zita reKemikari: Olmesartan Medoxomil

CAS: 144689-63-4

Kuchena:> 99.5% (HPLC)

Chitarisiko: Chichena kusvika Chinenge Chichena Cyrstalline Powder

Angiotensin II Receptor Antagonist.Anti-Hypertensive

E-Mail: alvin@ruifuchem.com


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Tsanangudzo:

Chemical Properties:

Chemical Name Olmesartan Medoxomil
Mashoko anoreva zvakafanana 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H- imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl) methyl Ester;CS-866
Nhamba yeCAS 144689-63-4
Nhamba yeCAT RF-PI1730
Stock Status MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula C29H30N6O6
Molecular Weight 558.60
Melting Point 180 ℃ (Zvita.)
Mvura Solubility Insoluble muMvura;Zvishoma Soluble muDMSO
Brand Ruifu Chemical

Zvinotsanangurwa:

Item Zvinotsanangurwa
Chitarisiko Ichena kusvika Kunenge Ichena Cyrstalline Powder
Identification IR, HPLC, UV: Inofanirwa Kuenderana neReference Standard
Kuchena / Analysis Method > 99.5% (HPLC paAnhydrous uye Solvent-Free Basis)
Kurasika paKuomesa <0.50%
Residue paIgnition <0.10%
Related Substances
Olmesartan RRT 0.2 <0.50%
Olmesartan Medoxoil Inoenderana Compound A. RRT 0.7 <0.20%
Olefinic Kusachena RRT 1.6 <0.50%
N-Alkyl Kusachena RRT 3.4 <0.10%
Chero Kumwe Kusachena <0.10%
Zvose Zvisina Kuchena <0.50%
Heavy Metals (as Pb) <10ppm
pH yeSolution (2%, W/V) 4.5 kusvika 6.5
Test Standard Enterprise Standard;USP Standard
Usage API

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

1

FAQ:

Application:

Olmesartan Medoxomil (CS-866) (CAS: 144689-63-4) ine simba uye inosarudza angiotensin II mhando 1 (AT (1)) receptor antagonist ine IC50 ye66.2 μM., inoshandiswa mukurapa kwepamusoro yeropa.Inoshandiswa se anti-hypertension.Olmesartan inoshanda nekuvhara kusungwa kweangiotensin II kune AT1 receptors muvascular tsandanyama.Nekuvharira kusunga kwete kuumbwa kweangiotensin II, Olmesartan inhibits yakashata yekutonga mhinduro pane renin secretion.Olmesartan Medoxomil ndeye pro-drug iyo inobviswa esterified kune inoshanda metabolite, olmesartan.Olmesartan Medoxomil yakatangwa muUS seBenicar, mushonga unopihwa nemuromo wehypertension.

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