Palonosetron Hydrochloride CAS 135729-62-3 Kuchena >99.0% (HPLC) (T) API Factory

Tsanangudzo Pfupi

Zita reKemikari: Palonosetron Hydrochloride

CAS: 135729-62-3

Chitarisiko: Muchena kana Kunze-Ichena Crystalline Powder

Kuchena: > 99.0% (HPLC) (T)

Palonosetron Hydrochloride ine simba zvakanyanya, inosarudza uye inoshanda nemuromo 5-HT3 receptor antagonist inoshandiswa mukudzivirira uye kurapwa kwechemotherapy-induced nausea uye kurutsa (CINV).Antiemetic.

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

Inquiry: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Commerce Supply Palonosetron Hydrochloride uye Related Intermediates:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API

Chemical Properties:

Chemical Name	Palonosetron Hydrochloride
Mashoko anoreva zvakafanana	Palonosetron HCl;(S,S)-Palonosetron Hydrochloride;RS-25259;RS25259 197;(S)-2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-Hexahydro-1H-Benzo[de]isoquinolin-1-one Hydrochloride;(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-Hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride ;Aloxi;Onicit
Nhamba yeCAS	135729-62-3
Nhamba yeCAT	RF-API03
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C19H24N2O·HCl
Molecular Weight	332.87
Chimiro Chokudzivisa	Heat Sensitive
Melting Point	307℃ (Zvita.)
Solubility mumvura	Yakanyatso Soluble mumvura
Solubility	Yakanyanya Kunyungudika muEthanol
Shipping Temperature	Ambient Temperature
COA & MSDS	Available
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Ichena kana Isina-White Crystalline Powder
Palonosetron Hydrochloride	>99.0% (HPLC) (T)
Kutenderera kwakananga [α]20/D	-98.0°～-104.0°
Identification	Wedzera BiI7K4, Gadzira Orange Yellow Precipitate
Identification	TLC Inopindirana neReference Substance
Identification	IR Inopindirana neStandard IR
Identification	Kuzivikanwa seChloride
Solubility	Yakasununguka Soluble mumvura, zvishoma soluble muMethanol, zvishoma zvishoma soluble mu ethanol, isinganyunguriki muacetone.
Kujeka uye Rudzi rweKugadzirisa	Max.Yero Nhamba 2 Standard Rudzi Solution
pH Vaule	4.5~6.5 (10mg/ml)
Zvinoenderana Nemamiriro ezvinhu
Related Compound A (NO)	<0.10%
Related Compound B (Ene-NO)	<0.10%
Related Compound C (S,R)	<0.10%
Related Compound D (R,S)	<0.50%
Palonosetron Enantiomer	<0.10%
Related Compound E (3-Ene)	<0.50%
Kusachena Kusina Kutaurwa	<0.10%
Residual Solvents
Ethanol	<3000ppm
Tetrahydrofuran	<5000ppm
DMF	<880ppm
Normal Hexane	<290ppm
Methyl Doro	<3000ppm
Isopropanol	<5000ppm
Methylbenzene	<890ppm
Mvura	<0.30%
Residue paIgnition	<0.20%
Kurasika paKuomesa	<1.00%
Heavy Metals	<10ppm
Test Standard	United States Pharmacopoeia (USP);European Pharmacopoeia (EP)
Usage	Palonosetron Hydrochloride API;5-HT3 Antagonist;CINV

Package & Kuchengeta:

Package: Bhodhoro, Kadhibhodhi Drum, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.

Kuchengeta:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.

Zvakanakira:

FAQ:

Application:

Palonosetron Hydrochloride (CAS: 135729-62-3) mushonga wekudzivisa kusvotwa uye kurutsa, iyo rudzi rutsva rwakanyanya kusarudza, high-affinity 5-HT3 receptor antagonist inogona kuvhara kurutsa reflex centre peripheral neurons presynaptic 5-HT.Receptor excitement inobata zvakananga iyo central nervous system mu5-HT.Impulse receptor excitement inogadzirwa nebasa revagal afferent nerve mushure menzvimbo, ichivharira vagus nerve endings mugut, kudzivirira zviratidzo ku5-HT.Receptor trigger zone inogona kuderedza chiitiko chekusvotwa uye kurutsa.Central Clinically kurapwa kweacute emetogenic chemotherapy yakakonzera kunonoka kusvotwa uye kurutsa.Nekuda kweiyo yakanyanya kurapa mhedzisiro, diki mhedzisiro, refu hafu yehupenyu (inenge 40 h), diki dosi, uye zvichingodaro, yakwezva kutarisisa kwakawanda.

Ne 1,2,3,4-Tetrahydro-1-Naphthoic Acid sechinhu chekutanga, kupatsanurwa, amination, kuderedza, cyclization, munyu wepalonosetron hydrochloride granisetron.Zvidzidzo zvekiriniki zvakaratidza kuti palonosetron inogona kushandiswa zvakachengeteka ne corticosteroids, analgesics, antiemetics, antispasmodics uye anticholinergic zvinodhaka sechinhu chekutanga, kupatsanurwa, amination, kuderedza, cyclization, munyu wepalonosetron hydrochloride granisetron.