Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Assay 97.5 ~ 102.0% Factory
Ruifu Chemical Supply With High Purity
Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1
N-Methyl Paroxetine CAS 110429-36-2
| Chemical Name | Paroxetine Hydrochloride Hemihydrate |
| Mashoko anoreva zvakafanana | (3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate;Paxil;Seroxat;BRL29060 Hydrochloride Hemihydrate;BRL29060A Hemihydrate;Paroxetine-D4 HCl |
| Nhamba yeCAS | 110429-35-1 |
| Nhamba yeCAT | RF-PI1946 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C19H20FNO3·HCl·1/2H2O |
| Molecular Weight | 374.84 |
| Melting Point | 140.0~143.0℃ |
| Kutenderera kwakananga [α]20/D | -88.0° kusvika -92.0° (C=1, MeOH, Calcd.on anh.substance) |
| Solubility | Inenge isinganyungudike mumvura;Yakanyanya Soluble muDimethylformamide, Methanol;Soluble muEthanol |
| Brand | Ruifu Chemical |
| Zviri mukati | Zvinotsanangurwa | Results |
| Chitarisiko | Ichena kana Inenge Yakachena Crystalline Powder | Conform |
| Identification A | Iyo infrared absorption spectrum inofanirwa kuenderana nereferenzi spectrum | Conform |
| Kuzivikanwa B | Nzvimbo huru yepamusoro uye nguva yekuchengetedza yemhinduro yebvunzo inofanirwa kuenderana nereferensi mhinduro | Conform |
| Chiziviso C | Mvura (neKF) | Conform |
| Kuzivikanwa D | Reaction yeClorides | Conform |
| Kusachena D | ≤0.20% | Absent |
| Kusachena G | ≤0.001% | |
| Related Substances | Kusachena A: ≤0.30% | 0.03% |
| Kusvibiswa Kusina Kutaurwa: Pakusachena kwega kwega, ≤0.10% | 0.06% | |
| Zvose Zvisina Kuchena: ≤0.50% | 0.10% | |
| Heavy Metals | ≤0.002% | <0.002% |
| Mvura (neKF) | 2.20%~2.70% | 2.46% |
| Sulfated Ash | ≤0.10% | <0.10% |
| Assay | 97.5% ~ 102.0% (Anhydrous Substance) | 100.2% |
| Residual Solvents | ||
| Methanol | ≤0.30% | 0.001% |
| Acetone | ≤0.50% | 0.001% |
| Isopropanol | ≤0.50% | 0.04% |
| Dichloromethane | ≤0.06% | Hapana |
| Toluene | ≤0.089% | 0.003% |
| Mhedziso: Kuenderana neEP7.0. | ||
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro
Paroxetine Hydrochloride Hemihydrate (CAS: 110429-35-1) ndeimwe yeakanyanya simba uye anosarudza sarudzo ye serotonin reuptake inhibitors (SSRI);antidepressant.Inonzi phenylpiperidine derivative, ine simba uye inosarudza ST (serotonin transporter/5-HT) uptake inhibitor.Inoshanda nekusunga ku ST (serotonin transporter / SERT) ine hukama hwepamusoro (Ki = 05 nM).Antidepressant uye anxiolytic in vivo.Paroxetine hydrochloride inogona kushandiswa kurapa kuora mwoyo, inova mushonga mutsva unodzvinyirira.Inogona zvakare kushandiswa kurapa kuvhunduka, generalized kusagadzikana kusagadzikana, kushushikana kwemagariro kusagadzikana, obsessive-compulsive disorder (OCD), kushaya hope, premenstrual syndrome, premenstrual ejaculation uye zvimwe zvirwere, zvine kurapa kwakanaka mhedzisiro uye kushoma kuita kwakashata.Rapa marudzi ese ekuora mwoyo.Kusanganisira kuora mwoyo nekuzvidya mwoyo uye reactive depression.Zviratidzo zvinowanzoitika zvekuora mwoyo: kuneta, kukanganisa kurara, kusava nehanya uye kufara mumabasa ezuva nezuva, kurasikirwa kwechido.Mushure mekunge mushonga wekurapa wagutsikana, unogona kudzivirira kudzoka kwekuora mwoyo.
