Posaconazole CAS 171228-49-2 API Factory Triazole Antifungal Agent High Quality
Factory Supply Posaconazole Related Intermediates, Commercial Production
Posaconazole CAS 171228-49-2
Posaconazole Yepakati POA CAS 149809-43-8
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate CAS 184177-81-9
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+)-Tartrate CAS 87-91-2
Chemical Name | Posaconazole |
Mashoko anoreva zvakafanana | POS;SCH 56592;4-- [4--[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl] methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one |
Nhamba yeCAS | 171228-49-2 |
Nhamba yeCAT | RF-API77 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
Molecular Formula | C37H42F2N8O4 |
Molecular Weight | 700.78 |
Density | 1.36 g/cm3 |
Solubility | Soluble muDMSO, Insoluble mumvura |
Shipping Condition | Yakatumirwa Pasi peAmbient Temperature |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika kuOff-White Crystalline Powder |
Identification A | IR: Iyo infrared absorption spectrum yechigadzirwa inofanira kuenderana neiyo yezvinhu zvinorehwa. |
Kuzivikanwa B | HPLC Kuchengeta nguva yakafanana nereferenzi chinhu |
Melting Point | 167.0~171.0℃ |
Chaidzo Kutenderera [a]20 | -24.0° ~ -28.0° (C=1, CHCL3) |
Mvura (KF) | ≤1.0% |
Residue paIgnition | ≤0.10% |
Related Substances | |
HT 909-24 | ≤0.20% |
Chero Kusachena Kwemunhu | ≤0.10% |
Zvose Zvisina Kuchena | ≤1.0% |
Residual Solvents | |
Methanol | ≤3000ppm |
Methyl tert-Butyl Ether | ≤5000ppm |
Isopropanol | ≤5000ppm |
Dimethyl Sulfoxide | ≤5000ppm |
Dichloromethane | ≤600ppm |
Assay | 98.0% ~ 102.0% (Yakaverengerwa pane yakaomeswa hwaro) |
Heavy Metals | ≤10ppm |
Isomer | Enantiomer ≤0.10% |
Chero Kusachena Kwemunhu ≤0.10% | |
Zvose Zvisina Kuchena ≤1.0% | |
Test Standard | Enterprise Standard;USP;BP;EP Standard |
Usage | API, Triazole Antifungal Agent |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Posaconazole (CAS 171228-49-2), yakakura-spectrum, yechipiri chizvarwa, triazole musanganiswa ine antifungal chiitiko, yakatangwa muUK, ndiyo nhengo nyowani yeazole kirasi yeantifungal agents kusvika kumusika.Inoratidzwa pakurapa uye kudzivirira kwehuwandu hwehutachiona hwehutachiona hwehutachiona, hunosanganisira aspergillosis, fusariosis, chromoblastomycosis, mycetoma, uye coccidiomycosis kune varwere vanoramba, kana kusashivirira, kurapa kwakajairika neamphotericin B uye/kana itraconazole.MuUS, inotenderwa kudzivirira hutachiona hweAspergillus uye Candida muvarwere vane makore gumi nematatu ezera vari panjodzi huru yekutapukirwa nehutachiona uhu nekuda kwekusabatwa zvakanyanya.Uyezve, inobvumirwa kurapa oropharyngeal candidiasis.Posaconazole ine yakawedzera kuwanda kwekuita pamusoro pedzimwe nhengo dzeazole antifungals.Pamusoro pekuita kwakasimba kunopesana neaspergillosis uye fluconazole-resistant Candida, inoratidza basa rinopesana neZygomycetes.Posaconazole inonzi triazole antifungal drug inotengeswa muUnited States neSchering-Plough pasi pezita rekutengesa Noxafil.