Potassium Bis(trimethylsilyl)amide CAS 40949-94-8 (0.5M Solution muToluene)
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Chemical Name | Potassium Bis (trimethylsilyl) amide |
Mashoko anoreva zvakafanana | Hexamethyldisilazane Potassium Munyu;Potassium Hexamethyldisilazane;KHMDS |
Nhamba yeCAS | 40949-94-8 |
Nhamba yeCAT | RF-PI2227 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C6H18KNSi2 |
Molecular Weight | 199.49 |
Boiling Point | 111℃ |
Density | 0.877 g/mL pa25℃ |
Hazard Kirasi | 3 (8);Mvura Inopisa, Inoparadza |
Packing Group | II |
Solubility | Miscible NeTerahydrofuran, Ether, Benzene uye Toluene |
Mvura Solubility | Reacts Nemvura |
Hydrolytic Sensitivity | 8: Inoita Nekukurumidza Nekunyorova, Mvura, pProtic Solvents |
Kugadzikana | Kunyorova, Kunzwa Mhepo, Kunzwa Kupisa.Chengetedza Pasi peNitrogen.Inogona Kugadzira Kunaya.Ambient Temperature. |
Safety | Njodzi-Imwe Yekuwedzera Njodzi Yekutakura Zvinhu Muchaja Inogona Kushandiswa |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Yero kuBrown Liquid |
Zvimwe Zvisina Kuchena | ≤3.00% |
Zvemukati zveActive Base | 0.45~0.55 M |
Test Standard | Enterprise Standard |
Package:Bhodhoro, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Inonzwa kune unyoro nemhepo.Chengeta munzvimbo inotonhorera.Chengeta chigadziko chakavharwa zvakasimba munzvimbo yakaoma uye ine mhepo yakanaka.Magaba anenge akavhurwa anofanirwa kunyatsovharwa uye kugara akati twasu kudzivirira kudonha.Bata uye chengetedza pasi pegesi inert.Hazvienderani neakasimba oxidizing agents.
Hazard Statements:Mvura inobvira zvikuru uye mhute.Zvinokonzera kupisa kwakanyanya kweganda uye kukuvara kwemaziso.Zvinokonzera kukuvara kwakanyanya kwemaziso.Kufungidzirwa kukuvadza mbereko kana mwana asati azvarwa.Inogona kukonzera kukuvara kunhengo kuburikidza nekuratidzwa kwenguva refu kana kudzokororwa.Inogona kukonzera kukotsira kana dzungu.
Potassium Bis(trimethylsilyl)amide (0.5M Solution muToluene) (inowanzo kupfupikiswa seKHMDS) (CAS: 40949-94-8) yakasimba, isiri-nucleophilic base ine pKa ye26 (kuenzanisa ne lithium diisopropylamide, pa36). )Inowanikwa pakutengesa sechinhu chakasimba uye semushonga mune zvakasiyana siyana zvinonyungudutsa (ex. THF, 2Me-THF, toluene, uye MTBE).Mareagents akafanana anosanganisira lithium bis (trimethylsilyl) amide (LiHMDS) uye sodium bis (trimethylsilyl) amide (NaHMDS).Non-nucleophilic megasteric yakasimba base.Pharmaceutical intermediates, inoshandiswa mukugadzira synthetic cephalosporins.KHMDSikemikari reagent inoshandiswa mukugadzirira yakakwirira-inoshanda liquid chromatography.Inoshandiswa kuumba yakagadzikana ma complexes ane potassium, ayo anobva aparadzaniswa nekoromo.KHMDS inoshandiswawo mukutsvagisa biochemical uye seasymmetric synthesis catalyst.KHMDS chigadziko chakasimba chinoshandiswa mualkylation carbonyl compounds.KHMDS inoshandiswa mukugadzirira kwe5-Azacytidine, an antineoplastic drug.Inoshandiswawo mukugadzirira kwe β3-AR agonists inoshandiswa mukurwisa-stress formulations.Iyo inoshandiswawo se reagent mukugadzirira kwe lanthanide complexes inoshandiswa mukusarudza cyclization maitiro.