Pregabalin CAS 148553-50-8 Kuchena >99.0% (HPLC) Antiepileptic API
Mugadziri ane High Purity uye Commerce Production
Zita reKemikari: PregabalinCAS: 148553-50-8
Pregabalin ndeyechipiri-chizvarwa antiepileptic drug (AED)
Chemical Name | Pregabalin |
Mashoko anoreva zvakafanana | (S) -3-(Aminomethyl) -5-Methylhexanoic Acid;PD-144723;PD144723;CI 1008;CI-1008;Lyrica |
Nhamba yeCAS | 148553-50-8 |
Nhamba yeCAT | RF-API57 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C8H17NO2 |
Molecular Weight | 159.23 |
Melting Point | 194.0 ~ 196.0℃ |
Solubility mumvura | Inoita Insoluble muMvura |
Solubility | Yakanyanya Kunyungudika muEthanol |
Shipping Condition | Under Ambient Temperature |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika kuOff-White Crystalline Powder |
Identification | IR: Yakafanana neReference Substance |
Specific Rotation | +10.0°~+13.0° (C=1, Mvura) |
Kurasika paKuomesa | <0.50% |
Sulfated Ash | <0.10% |
Related Substances | Kusachena A <0.15% |
Kusvibiswa Kusina Kutaurwa Kunopera Pamberi pePregabalin (bvunzo A) <0.10% | |
Kusvibiswa Kusina Kutaurwa Kunopera Mushure mePregabalin (bvunzo B) <0.10% | |
Yese yebvunzo A uye B <0.50% | |
Purity By HPLC R-Isomer | <0.15% |
Heavy Metals (as Pb) | <10ppm |
Chlorides (Cl) | <0.05% |
Residual Solvents | |
Isopropyl Doro | <5000ppm |
Ethyl Acetate | <5000ppm |
Tetrahydrofuran | <250ppm |
Isopropyl Ether | <500ppm |
Ethanol | <1000ppm |
Kuchena / Analysis Method | > 99.0% (HPLC pane yakaomeswa) |
Test Standard | Enterprise Standard |
Usage | Antiepileptic Drug API |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza & mwando
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Pregabalin chizvarwa chechipiri antiepileptic drug (AED) inozivikanwa nezita rezita reLyrica (Pfizer, Tadworth) muUK neUSA, ine γ-amino butyric acid chimiro pane yayo molecular chimiro, ine anticonvulsant mhedzisiro, uye iri. yakabudirira kugadzirwa nekambani Pfizer yekurapa kweperipheral neuropathic pain, kana adjuvant kurapwa kwekubatwa kwechikamu.Pregabalin is Anticonvulsant uye antiepileptic drug inoshandiswa kurapa pfari, neuropathic pain, fibromyalgia, uye generalized kusagadzikana kusagadzikana.Kushandiswa kwaro kwepfari kwakafanana nekuwedzera kurapa kwekubatwa nepfari uye kana pasina chechipiri generalization muvakuru.Muna Zvita 2008, US Food and Drug Administration (FDA) yakabvumidza pregabalin (zita rekutengesa "Lyrica") kuti irapwe diabetic peripheral neuropathic pain (DPN) uye postherpetic neuralgia (PHN) anove Maviri anonyanya kuzivikanwa neuropathic marwadzo.Pregabalin ine chiratidzo chinotenderwa uye inoshandiswa zvakanyanya pakurapa generalized kusagadzikana kusagadzikana.Miedzo yakati wandei, yakapetwa kaviri-mapofu, inodzorwa ne placebo yakawana kuti pregabalin kurapa kunoshanda kune varwere vane generalized kusagadzikana kusagadzikana uye magariro kusagadzikana kusagadzikana.Dose titration Epilepsy-adjunctive therapy: 25 mg bd kwemazuva manomwe, kuwedzerwa ne50 mg mazuva manomwe oga oga;nguva dzose kuchengetedza 300 mg zuva nezuva, yakakamurwa kuva 2 kana 3 doses (max. 600 mg zuva nezuva, yakakamurwa kuva 2 kana 3 doses).Generalized fungal disorder: 150 mg zuva nezuva, yakakamurwa kuva 2 kana 3 doses, kwemazuva 7, kuti iwedzere ne 150 mg mazuva ose e7 (max. 600 mg zuva nezuva, yakakamurwa kuva 2 kana 3 doses).Kana ukamisa pregabalin, zvinokurudzirwa kuti uite tepi kweinenge vhiki imwe kuti udzivise kubvisa kamwe kamwe.Yambiro Varwere vane mamiriro anogona kukonzera encephalopathy.Varwere vane yakanyanya congestive heart failure.
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