Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Purity ≥98.5% (GC) Vonoprazan Fumarat Intermediate Factory
Supply Vonoprazan Fumarate uye Related Intermediate
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Chemical Name | Pyridine-3-Sulfonyl Chloride |
| Mashoko anoreva zvakafanana | 3-Pyridinesulfonyl Chloride;3-Pyridylsulfonyl Chloride;m-Pyridinesulfonyl Chloride;Piperidine-3-Sulfonylchloride |
| Nhamba yeCAS | 16133-25-8 |
| Nhamba yeCAT | RF-PI540 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C5H4ClNO2S |
| Molecular Weight | 177.61 |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Isina Ruvara kana Pale Yellow Liquid |
| Kuchena / Analysis Method | ≥98.5% (GC) |
| Boiling Point | 110.0 ~ 112.0℃/2mm Hg |
| Kusachena Kumwechete | ≤0.50% |
| Zvose Zvisina Kuchena | ≤1.5% |
| Test Standard | Enterprise Standard |
| Usage | Pakati peVonoprazan Fumarate (CAS: 1260141-27-2) |
Package: Bhodhoro, 25kg / Barrel, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro.
Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) iri pakati peVonoprazan Fumarate (CAS: 1260141-27-2).Vonoprazan Fumarate, yakawanikwa uye yakagadziridzwa naTakeda naOtsuka, yakagamuchirwa nePMDA yeJapan muna Zvita 2014, uye inoratidzwa pakurapa gastric ulcer, duodenal ulcer uye reflux esophagitis.Vonoprazan fumarate ine nzira itsva yekuita inonzi potassium-competitive acid blockers, iyo inodzivisa kusungwa kwe potassium ions kuH +, K + -ATPase (inozivikanwawo seproton pump) muchikamu chekupedzisira chegastric acid secretion mugastric parietal cells.Vonoprazan haidziviriri basa reNa +, K + -ATPase kunyange pazvikamu 500 nguva dzakakwirira kudarika iyo yeIC50 tsika dzavo pamusoro pegastric H +, K + -ATPase basa.Uyezve, mushonga wacho hauna kukanganiswa negastric secretory state, kusiyana nePPIs.
