(R)-(-)-3-Quinuclidinol CAS 25333-42-0 Kuchena ≥99.0% Chiral Purity ≥99.0%
Chemical Name | (R)-(-)-3-Quinuclidinol |
Mashoko anoreva zvakafanana | (R)-3-Quinuclinol |
Nhamba yeCAS | 25333-42-0 |
Nhamba yeCAT | RF-CC117 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C7H13NO |
Molecular Weight | 127.18 |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | White kana Off-White Powder |
Kuzivikanwa RT (neGC) | Ita zvinoenderana neReference Standard |
Melting Point | 212.0~224.0℃ |
Chaicho Kutenderera [α]D20 | -40.0°~ -48.0° |
Kunyorova (KF) | ≤0.50% |
Residue paIgnition | ≤0.50% |
Kuchena | ≥99.0% |
Zvose Zvisina Kuchena | ≤1.00% |
Chiral Purity | ≥99.0% |
Enantiomer | ≤1.00% |
Assay | 98.0%~101.0% (paAnhydrous Basis) |
Test Standard | Enterprise Standard |
Usage | Chiral Compounds;Pharmaceutical Intermediates |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza & mwando
Shanghai Ruifu Chemical Co., Ltd ndiyo inotungamira mugadziri uye mutengesi we (R)-(-)-3-Quinuclidinol (CAS: 25333-42-0) ine mhando yepamusoro, inoshandiswa zvakanyanya muorganic synthesis, synthesis yemishonga yepakati uye. Active Pharmaceutical Ingredient (API) synthesis.(R)-(-)-3-Quinuclidinol inogona kushandiswa seyepakati mukubatanidzwa kweAPI (CAS: 242478-38-2).(CAS: 242478-38-2) mushonga unorwisa muscarinic unoshandiswa kurapa dundira rinokonzera zviratidzo zvekuwanda, kukurumidza, kana kusagadzikana.(CAS: 242478-38-2) ndeye M3 muscarinic receptor antagonist iyo yakagadzirwa uye yakatangwa kuti irapwe bladder yakawandisa (pollakiuria) muEurope.M3 receptors yakave yakabatanidzwa mune neurally evoked yakatsetseka tsandanyama kubvongodzwa kwebladder, uye M2 receptors yakafungidzirwawo kuita basa nekuda kwehutongi hwavo mu detrusor tsandanyama.Iyo synthesis ye solifenacin inosanganisira kugadzirira kweracemic 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline kuburikidza necyclization yeN-(2-Phenylethyl)benzamide, uye kunotevera kuita ne ethyl chloroformate uye transesterification ne (R) -3-Quinuclidinol. .Chiral chromatography inopa kuparadzaniswa kweiyo diastereomer inodiwa.Neimwe nzira, 1-Phenyl-1,2,3,4-Tetrahydroisoquinoline inogona kuiswa pasi pekugadziriswa kwemaziso ne (+) -Tartaric Acid isati yarapwa ne ethyl chloroformate uye inotevera transesterification.