Ramelteon (TAK-375) CAS 196597-26-9 Kuchena > 99.5% (HPLC)
Kutungamira Mugadziri uye Mutengesi, Pakati peRamelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-imwe CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
| Chemical Name | Ramelteon |
| Mashoko anoreva zvakafanana | (S)-N-[2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethyl]propionamide;TAK-375;TAK375;TAK 375;Rozerem |
| Nhamba yeCAS | 196597-26-9 |
| Nhamba yeCAT | RF2885 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C16H21NO2 |
| Molecular Weight | 259.35 |
| Melting Point | 113.0 kusvika 116.0 ℃ |
| Boiling Point | 455.3±24.0℃ |
| Density | 1.119±0.06 g/cm3 |
| Kutenderera kwakananga [α]20/D | -55.0° kusvika -60.0° (C=1, CHCL3) |
| Solubility mumvura | Isinganyungudika muMvura (11 mg/l 25℃) |
| Solubility | Soluble muEthanol, Methanol, DMSO |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | White Crystalline Powder |
| Kuchena / Analysis Method | >99.5% (HPLC) |
| Melting Point | 113.0~116.0℃ |
| Kurasika paKuomesa | <0.50% |
| Residue paIgnition | <0.10% |
| Isomer Purity | <0.10% |
| Heavy Metals | <10ppm |
| Acidity kana alkalinity | Conform |
| Ethanol | <5000ppm |
| Kusachena Kumwechete | <0.20% |
| Zvose Zvisina Kuchena | <0.50% |
| Infrared Spectrum | Inopindirana neChimiro |
| Test Standard | Enterprise Standard |
| Usage | API, Yakatenderwa Kurapwa kweInsomnia |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro
Kutenga sei?Please contactDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Makore 15 Oupenyu?Tine makore anopfuura 15 ane ruzivo mukugadzira uye kutumira kunze kwemhando dzakasiyana-siyana dzepamusoro dzemishonga yepakati kana makemikari akanaka.
Main Markets?Tengesa kumusika wepamba, North America, Europe, India, Korea, Japan, Australia, nezvimwe.
Zvakanakira?Hunhu hwepamusoro, mutengo unokwanisika, masevhisi ehunyanzvi uye rutsigiro rwehunyanzvi, kuendesa nekukurumidza.
HunhuSimbiso?Strict quality control system.Midziyo yehunyanzvi yekuongorora inosanganisira NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, nezvimwe.
Samples?Zvigadzirwa zvakawanda zvinopa mahara emahara ekuongorora kwemhando, mutengo wekutumira unofanirwa kubhadharwa nevatengi.
Factory Audit?Factory audit inogamuchirwa.Ndapota itai nguva isati yasvika.
MOQ?Hapana MOQ.Kurongeka kudiki kunogamuchirwa.
Delivery Nguva? Kana mukati me stock, mazuva matatu kutumirwa anovimbiswa.
Transportation?Ne Express (FedEx, DHL), neMhepo, neGungwa.
Zvinyorwa?Mushure mekutengesa sevhisi: COA, MOA, ROS, MSDS, nezvimwe zvinogona kupihwa.
Custom Synthesis?Inogona kupa echinyakare synthesis masevhisi kuti aenderane nezvinodiwa zvako zvekutsvagisa.
Payment Terms?Proforma invoice inozotumirwa kutanga mushure mekusimbisa kurongeka, yakavharirwa ruzivo rwedu rwebhangi.Kubhadhara neT/T (Telex Transfer), PayPal, Western Union, nezvimwe.
Ramelteon (CAS: 196597-26-9) yakatanga kutenderwa neUS Food and Drug Administration (FDA) musi waChikunguru 22, 2005, ndokuzotenderwa nePharmaceuticals and Medical Devices Agency (PMDA) musi wa16 Kubvumbi 2010. Yakagadzirwa uye inotengeswa seRozerem® naTakeda,inogona kushandiswa kurapa kushaya hope nedambudziko rekukotsira, uye ine mhedzisiro yekusagona kusingaperi uye kushaya hope kwenguva pfupi.Ichi chigadzirwa chinogona kusarudza kumisa mhando 1 uye mhando 2 receptors ye melatonin (MT1, MT2), kuwedzera inononoka wave kurara (SWS) uye nekukurumidza kwekufamba kwemaziso kurara (REW), nekudaro kuderedza kushaya hope.Ramelteamide ndiyo yekutanga isiri-inopindwa muropa yekurapa insomnia mushonga iyo isiri pasi pehutongi hwakakosha.Ichi chigadzirwa ndeye melatonin receptor agonist.Iine hukama hwepamusoro ne melatonin MT1 uye MT2 receptors, uye ine chaiyo uye yakakwana agonistic effect paMT1 uye MT2 receptors, asi haipindirani neMT3 receptor.Mukuwedzera, haisungiri kune neurotransmitter receptors yakadai seGABA receptor complexes, uye haipindiri nebasa rema enzymes akawanda mukati mehumwe huwandu.Nokudaro, inogona kudzivisa kukanganisa kunobatanidza nemishonga yeGABA (iyo inogona kukonzera njodzi dzemotokari, kuwira uye kuputsika).Etc.) uye kupindwa muropa nezvinodhaka uye kuvimba.Rozerem® inowanikwa sefirimu-yakavharwa piritsi rekushandisa nemuromo, ine 8 mg yemahara Ramelteon.Iyo yakakurudzirwa yevakuru dose ndeye 8 mg inotorwa mukati me30 maminetsi ekuenda kunorara.
