Rapamycin Sirolimus RAPA CAS 53123-88-9 Assay ≥98.5% API Factory High Purity
Mugadziri ane Kuchena Kwepamusoro uye Hwakagadzikana Hunhu
Kemikari Zita: Rapamycin;Sirolimus;RAPA
CAS: 53123-88-9
Macrolide Immunosuppressive Agent
API High Quality, Commercial Production
Chemical Name | Rapamycin |
Mashoko anoreva zvakafanana | Sirolimus;RAPA;AY-22989 |
Nhamba yeCAS | 53123-88-9 |
Nhamba yeCAT | RF-API59 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
Molecular Formula | C51H79NO13 |
Molecular Weight | 914.19 |
Melting Point | 183.0~185.0℃ |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kana Isina-White Crystalline Powder |
Identification A | Iyo IR spectrum ye potassium bromide kugadzirira yemuenzaniso inoratidza maxima paakaenzana wavelengths seiyo yekugadzirira kwakafanana kwemukati-mumba referensi standard. |
Kuzivikanwa B | Iyo UV spectrum ye95% ethanol gadziriro yemuenzaniso inoratidza maxima pa267nm, 277nm, 288nm seyakafanana gadziriro ye-in-house reference standard. |
Chiziviso C | Nguva yekuchengeta yekumusoro kweiyo trans-uye cis-stereoisomers muchromatogram yeassay kugadzirira inoenderana neiyo iri muchromatogram yegadziriro yakajairwa, sezvakawanikwa muyedzo. |
Optical Rotation | -147.0°~ -157.0° |
Kurasika paKuomesa | ≤0.50% |
Residue paIgnition | ≤0.20% |
Heavy Metals | ≤20ppm |
Kusachena Kwemunhu | ≤1.5% |
Zvose Zvisina Kuchena | ≤2.0% (kusanganisa Cis-Stereoisomer yeSirolimus) |
Cis-Stereoisomer yeSirolimus | ≤5.0% |
Residual Solvents | |
Ethanol | ≤5000ppm |
Ethyl Acetate | ≤5000ppm |
Cyclohexane | ≤5000ppm |
Acetone | ≤5000ppm |
Diethyl Ether | ≤5000ppm |
Assay | ≥98.5% (Yakaverengerwa trans- uye cis-stereoisomer ye sirolimus pane yakasarudzika) |
Test Standard | Chinese Pharmacopoeia (CP);Enterprise Standard |
Usage | Active Pharmaceutical Ingredient (API) |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Rapamycin (Sirolimus; AY 22989) is autophagy activator, chimiro chitsva che macrolide immunosuppressive agent ine yakanaka yekurapa mhedzisiro, yakaderera muchetura, uye isina nephrotoxicity.Inogona kushandiswa kuchengetedza kusadzivirirwa kwenhengo dzekutapurirana (kunyanya muitsvo transplants) kudzikisa kurambwa kweimmunological mushure mekuvhiyiwa kwenhengo.