Remdesivir GS-5734 CAS 1809249-37-3 COVID-19 API Yemhando yepamusoro

Tsanangudzo Pfupi

Kemikari Zita: Remdesivir (GS-5734)

CAS: 1809249-37-3

Chitarisiko: Ichena kusvika Kuchena-Ichena Solid Powder

Chiyero: 98.0% ~ 102.0%

Remdesivir yekurapa COVID-19

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com


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Tsanangudzo:

Chemical Properties:

Chemical Name Remdesivir
Mashoko anoreva zvakafanana GS-5734;2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano -3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Nhamba yeCAS 1809249-37-3
Nhamba yeCAT RF-API96
Stock Status MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram
Molecular Formula C27H35N6O8P
Molecular Weight 602.58
Density 1.47±0.1 g/cm3
Brand Ruifu Chemical

Zvinotsanangurwa:

Item Zvinotsanangurwa
Chitarisiko Ichena kusvika Kuchena-Ichena Solid Powder
Identification A IR: Iyo infrared absorption spectrum yechigadzirwa inofanira kuenderana neiyo yezvinhu zvinorehwa.
Kuzivikanwa B HPLC Kuchengeta nguva yakafanana nereferenzi chinhu
Specific Rotation -19.0° ~ -22.0°
Solubility Solunle muMethanol, Inonyungudika Zvishoma muEthanol, Inonyungudika zvishoma muAcetonitrile, Isinganyungudike mumvura
Related Substances
Chero Kusachena Kwemunhu ≤0.10%
Zvose Zvisina Kuchena ≤1.0%
RD-3.1 ≤0.10%
RD-C ≤0.10%
RD-D ≤0.10%
RD-E ≤0.10%
RP-Isomer ≤0.10%
Nitrophenol ≤0.10%
Residual Solvents
Methanol Dichloride ≤6000ppm
Acetone ≤5000ppm
Isopropyl Doro ≤5000ppm
Acetonitrile ≤410ppm
Dichloromethane ≤600ppm
Methyl tert Butyl Ether ≤5000ppm
Ethyl Acetate ≤5000ppm
Tetrahydrofuran ≤720ppm
n-Heptane ≤5000ppm
Assay 98.0% ~ 102.0% (Yakaverengerwa pane yakaomeswa hwaro)
Total Aerobic Counts
Aerobic Bacteria ≤100cfu/g
Mbiriso uye Mold ≤10cfu/g
E. Coil Negative
Bacterial Endotoxin ≤1.0EU
Heavy Metals ≤20ppm
Test Standard Enterprise Standard
Usage API, COVID-19

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.

Zvakanakira:

1

FAQ:

Application:

Remdesivir (CAS 1809249-37-3), inotengeswa pasi pezita rezita reVeklury, mushonga unorwisa utachiona wakagadzirwa nekambani yebiopharmaceutical yeGiriyedhi Sayenzi.Inoitwa kuburikidza nejekiseni mutsinga.Munguva yeCOVID-19 denda, remdesivir yakatenderwa kana kupihwa mvumo yekushandiswa kwekukurumidzira kurapa COVID-19 munyika dzinosvika makumi mashanu.Nhungamiro dzakagadziridzwa kubva kuWorld Health Organisation muna Mbudzi 2020 dzinosanganisira kurudziro yekupokana nekushandiswa kweRemdesivir kurapwa kweCOVID-19.Remdesivir yakatanga kugadzirwa kurapa hepatitis C, uye yakazoferefetwa nezvechirwere cheEbola virus uye Marburg virus utachiona isati yadzidzwa semushonga wekubatira hutachiona hweCOVID-19.Izvo zvinowanzoitika kune vanozvipira vane hutano zvinosimudza mazinga eropa echiropa enzymes (chiratidzo chezvinetso zvechiropa).Iyo inonyanya kukonzeresa muvanhu vane COVID-19 kusvotwa.Mhedzisiro inogona kusanganisira kuzvimba kwechiropa uye kuita kwakabatana-nekupinda nekusvotwa, kuderera kweropa, uye dikita.Remdesivir iprodrug inoitirwa kubvumira intracellular kuendeswa kweGS-441524 monophosphate uye inotevera biotransformation muGS-441524 triphosphate, ribonucleotide analogue inhibitor yeviral RNA polymerase.

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