Roflumilast CAS 162401-32-3 Assay 99.0~101.0% API

Tsanangudzo Pfupi

Zita reKemikari: Roflumilast

CAS: 162401-32-3

Chiyero: 99.0 ~ 101.0% (Ikaverengerwa pane Dried Basis)

Kuonekwa: Ichena kana Inenge Yakachena Crystalline Powder

API PDE-4 Inhibitor COPD

Bata: Dr. Alvin Huang

Nharembozha/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Ruifu Chemical Supply Roflumilast Intermediates:
Roflumilast CAS 162401-32-3
4-Amino-3,5-Dichloropyridine CAS 22889-78-7

Chemical Properties:

Chemical Name	Roflumilast
Mashoko anoreva zvakafanana	3-(Cyclopropylmethoxy)-N-(3,5-Dichloropyridin-4-yl)-4-(Ddifluoromethoxy)benzamide
Nhamba yeCAS	162401-32-3
Nhamba yeCAT	RF-PI2075
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C17H14Cl2F2N2O3
Molecular Weight	403.21
Density	1.471±0.060 g/cm3
Sensitivity	Heat Sensitive
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Ichena kana Inenge Yakachena Crystalline Powder
Solubility	Yemahara inonyungudika muacetone, isinganyungudika zvishoma muacetronitrile, isinganyungudika zvishoma muanhydrous ethanol, isinganyungudika mumvura.
Melting Point	157.0~162.0℃
Kurasika paKuomesa	<0.50%
Residue paIgnition	≤0.10%
Heavy Metals	≤10ppm
Chloride	≤0.01%
Kuzivikanwa A. UV	Iyo wavelength yekunyudza yakanyanya kunofanirwa kunge iri pa213 ~ 251nm
Kuzivikanwa B. IR	Iyo IR yekunyudza spectrum yemuenzaniso inoenderana neiyo yereferenzi imwe
Chiziviso C.	Inoratidza kuita kweFluoride
Related Substances
Kusachena Kumwechete	≤0.10%
Zvose Zvisina Kuchena	<0.50%
Residual Solvents
Tert-Butanol	<0.10%
Tetrahydrofuran	<0.072%
Toluene	<0.089%
N, N-Dimethylformamide	<0.088%
Assay	99.0 ~ 101.0% (Yakaverengerwa paDried Basis)
Test Standard	Enterprise Standard
Usage	API;COPD

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro

Zvakanakira:

FAQ:

Application:

Roflumilast (CAS: 162401-32-3) inosarudza oral phosphodiesterase-4 (PDE-4) inhibitor uye benzamide compound.Yakagadzirwa nekambani yeGerman Altana muna 1993 uye ndiyo yega yemuromo PDE-4 inhibitor inoshandiswa kurapa zvirwere zvekufema zvakabvumidzwa kutengeswa.Roflumilast ndiyo yekutanga mushonga werudzi rwayo kunanga chirwere chakanyanya chisingaperi chinodzivirira pulmonary chirwere (COPD), uye zvakare ndiyo yekutanga yemuromo anti-inflammation mushonga wakanyatsogadzirirwa varwere veCOPD.Yayo yakasiyana-siyana inogona kubatsira kugadzirisa COPD: kana yakashandiswa pamwe chete nebronchodilators kurapa varwere vakanyanya kuoma COPD, Roflumilast inogona kuva nemukana wekuwedzera kuderedza zviratidzo uye kuderera kwehuwandu, zvichiita kuti uve mushonga wekutanga unotarisana nevarwere vane kudzokorora kuparara kwe phenotype-spAecific COPD. uye kuvharika kwekuyerera kwemhepo kwakanyanya kunoenderana nekukosora kusingaperi uye phlegm yakawandisa.Kunze kwekuve kurapa kweCOPD yakaoma, Roflumilast inogona zvakare kushandiswa kudzivirira nekurapa zvipfuyo zvirwere zvekufema, kuwedzeredza mucosa bronchitis kukosora, asthmatic bronchitis, uye acute bronchitis uye air sacculitis inoperekedzwa neisina kujairika kufema turakiti secretion.