(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1 Ibrutinib Intermediate Purity >99.0% (GC)
Chemical Name | (S) -1-Boc-3-Hydroxypiperidine |
Mashoko anoreva zvakafanana | (S) -1-(tert-Butoxycarbonyl) -3-Hydroxypiperidine;(S)-1-Boc-3-Piperidinol |
Nhamba yeCAS | 143900-44-1 |
Nhamba yeCAT | RF-CC299 |
Stock Status | MuStock, Kukwanisa Kugadzira Matani makumi maviri / Mwedzi |
Molecular Formula | C10H19NO3 |
Molecular Weight | 201.27 |
Melting Point | 52.0 ~ 56.0℃ |
Solubility | Soluble muMethanol |
Kutenderera kwakananga [a]20/D | +9.0°~+11.0° (C=1 muChloroform) |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | White Powder kana Makristasi |
Chiral Purity | >99.5% (GC) |
Chemical Purity | >99.5% (GC) |
Mvura (KF) | ≤0.50% |
Methanol (GC) | ≤50ppm |
Ethanol (GC) | ≤50ppm |
DCM (GC) | ≤500ppm |
3-Hydroxypiperidine | ≤0.10% |
3-Hydroxypyridine | ≤0.20% |
1-Boc-3-Piperidone | ≤0.10% |
1-Boc-4-Hydroxypiperidine | ≤0.10% |
1.96 RRT | ≤0.20% |
Chero Kusachena Kusina Kutaurwa | ≤0.10% |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediates;Chiral Compounds |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro.
(S) -1-Boc-3-Hydroxypiperidine (CAS: 143900-44-1) inokosha chiral yepakati pekugadzirwa kweIbrutinib (CAS: 936563-96-1).Ibrutinib imhando yeBruton tyrosine kinase (BTK) inhibitor, inogona kushandiswa kurapa chronic lymphocytic leukemia (CLL) uye mantle cell lymphoma (MCL).MCL neCLL ndezveB-cell non-Hodgkin's lymphoma, iyo yakaoma kurapa uye nyore kudzokorora.Yakajairwa kemikari immunotherapy haina kunanga, inowanzoitika 3 kana 4 yakashata maitiro.Ibrutinib neB lymphocytes inogona kunanga neBTK iyo inofanirwa kuumbwa, kusiyanisa, uye kutapurirana kweruzivo, inhibit BTK chiitiko chisingachinjike, uye inhibit bundu cell kuwanda uye kurarama zvinobudirira.Ibrutinib inogona kukurumidza kunyura mushure mekutonga kwemuromo, panguva ye1 ~ 2h inosvika pahuwandu hwehuwandu hweropa, maitiro asina kunaka ndeemumwe kana maviri, saka, Ibrutinib ichava sarudzo itsva yekurapa kweCLL neMCL.