(S) -3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Kuchena ≥99.0% ee≥99.0% Palonosetron Hydrochloride Pakati
Commerce Supply Palonosetron Hydrochloride uye Related Intermediates:
(S)-1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
| Chemical Name | (S) -3-Aminoquinuclidine Dihydrochloride |
| Mashoko anoreva zvakafanana | (S)-(-)-3-Aminoquinuclidine 2 HCL |
| Nhamba yeCAS | 119904-90-4 |
| Nhamba yeCAT | RF-CC112 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C7H16Cl2N2 |
| Molecular Weight | 199.12 |
| Density | 1.24g/cm3 |
| Melting Point | 260 ℃ |
| Boiling Point | 470.4 ℃ pa760mmHg |
| Solubility mumvura | Soluble |
| Shipping Condition | Yakatumirwa Pasi peAmbient Temperature |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kusvika kuChiedza Yero yeCrystalline Powder |
| IR | Absorption Spectra Inopindirana neReference |
| Chloride Reaction | Positive Reaction |
| Kuchena (HPLC) | ≥98.0% |
| Kurasika paKuomesa | ≤0.50% |
| Chaicho Kutenderera [α]D20 | -22.0°~ -26.0° (C=1, H2O) |
| Heavy Metals | ≤20ppm |
| Storage | 5-8 ℃ Kudzivirira mhepo |
| Test Standard | Enterprise Standard |
| Usage | Palonosetron Hydrochloride (CAS: 135729-62-3) Pakati |
(S)-3-Aminoquinuclidine Dihydrochloride (CAS: 119904-90-4) Synthetic Route
Package: Bhodhoro, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi we (S) -3-Aminoquinuclidine Dihydrochloride (CAS: 2133-40-6) ine mhando yepamusoro.Iyo yemishonga yepakati kazhinji mune synthesis yePalonosetron Hydrochloride (CAS: 135729-62-3).
Palonosetron Hydrochloride (CAS: 135729-62-3) mushonga wekudzivisa kusvotwa uye kurutsa, iyo rudzi rutsva rwakanyanya kusarudza, high-affinity 5-HT3 receptor antagonist inogona kuvhara kurutsa reflex centre peripheral neurons presynaptic 5-HT.Receptor excitement inobata zvakananga iyo central nervous system mu5-HT.Impulse receptor excitement inogadzirwa nebasa revagal afferent nerve mushure menzvimbo, ichivharira vagus nerve endings mugut, kudzivirira zviratidzo ku5-HT.Receptor trigger zone inogona kuderedza chiitiko chekusvotwa uye kurutsa.Central Clinically kurapwa kweacute emetogenic chemotherapy yakakonzera kunonoka kusvotwa uye kurutsa.Nekuda kweiyo yakanyanya kurapa mhedzisiro, diki mhedzisiro, refu hafu yehupenyu (inenge 40 h), diki dosi, uye zvichingodaro, yakwezva kutarisisa kwakawanda.Ne 1,2,3,4-tetrahydro-1-naphthoic acid sechinhu chekutanga, kupatsanurwa, amination, kuderedza, cyclization, munyu wepalonosetron hydrochloride granisetron.Zvidzidzo zvekiriniki zvakaratidza kuti palonosetron inogona kushandiswa zvakachengeteka ne corticosteroids, analgesics, antiemetics, antispasmodics uye anticholinergic zvinodhaka sechinhu chekutanga, kupatsanurwa, amination, kuderedza, cyclization, munyu wepalonosetron hydrochloride granisetron.
