Sitagliptin Triazole Hydrochloride CAS 762240-92-6 Kuchena > 99.0% (HPLC) Factory High Quality
Supply Sitagliptin Phosphate Monohydrate Related Intermediates:
Sitagliptin API CAS 486460-32-6
Purogiramu inonzi Sitagliptin Phosphate Monohydrate CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Yepakati CAS 486460-21-3
Chemical Name | 3-(Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride |
Mashoko anoreva zvakafanana | sitagliptin Triazole Hydrochloride;Sitagliptin Yepakati A |
Nhamba yeCAS | 762240-92-6 |
Nhamba yeCAT | RF-PI1193 |
Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
Molecular Formula | C6H7F3N4·HCl |
Molecular Weight | 228.60 |
Melting Point | 236.0~246.0℃ |
Solubility | Soluble muMethanol |
Brand | Ruifu Chemical |
Item | Zvinotsanangurwa |
Chitarisiko | Ichena kusvika kuOff-White Crystalline Powder |
Kuzivikanwa neHPLC | Nguva yekuchengetedza yemuenzaniso inopindirana nereferensi standard |
Kuzivikanwa neIR | Zvinoenderana |
Kurasika paKuomesa | <0.50% |
Related Substances | |
Chero Kusachena Kumwe | <0.50% |
Zvose Zvisina Kuchena | <1.00% |
Heavy Metals | <20ppm |
Kuchena / Analysis Method | >99.0% (HPLC) |
Test Standard | Enterprise Standard |
Usage | Yepakati yeSitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Package: Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza uye unyoro.
3-(Trifluoromethyl) -5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride (CAS: 762240-92-6) iri pakati peSitagliptin Phosphate Monohydrate ( CAS: 654671-77-9), inova yemuromo-bioavailable yakasarudzwa DPP4 inhibitor yakawanikwa kuburikidza nekugadzirisa kwekirasi ye β-aminoacid-yakatorwa DPP4 inhibitors.Iyo inoderedza chiitiko cheDPP4 nenzira yakatsiga ichitevera kamwechete zuva nezuva kutonga, inochengetedza mazinga ekutenderera eGIP uye GLP1 anotevera kudya mune zvese acute uye zvisingaperi zvidzidzo uye inoderedza mazinga eglucose eropa pasina kuwedzera kwakanyanya mu hypoglycaemia.Sitagliptin Phosphate (STG) inoshandiswa kurapa DM Type 2 nekuti inovandudza glycemic control nekuwedzera mazinga eanoshanda incretin mahomoni, GLP-1 (peptide-1) uye GIP (glucose-inotsamira insulinotropic peptide).STG yakabvumidzwa neFDA muna 2006.