Sorafenib CAS 284461-73-0 Purity ≥99.0% (HPLC) API Factory High Quality
Commerce Supply Sorafenib Tosylate uye Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
| Zita | Sorafenib |
| Mashoko anoreva zvakafanana | Sorafenib Yemahara Base |
| Nhamba yeCAS | 284461-73-0 |
| Nhamba yeCAT | RF-API04 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram |
| Molecular Formula | C21H16ClF3N4O3 |
| Molecular Weight | 464.82 |
| Density | 1.454±0.06 g/cm3 |
| Solubility | Soluble muDMSO |
| Shipping Conditions | Ambient Temperature |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kusvika kuOff-White Powder |
| Kuchena / Analysis Method | ≥99.0% (HPLC) |
| Identification | H-NMR, MS |
| Kurasika paKuomesa | ≤1.0% |
| Residue paIgnition | ≤0.10% |
| Kusachena Kumwechete | ≤0.20% (HPLC) |
| Zvose Zvisina Kuchena | ≤1.0% (HPLC) |
| Heavy Metals | ≤20ppm |
| Kujeka Kwemhinduro | Conform to Standard |
| Test Standard | Enterprise Standard |
| Usage | RCC & HCC |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Sorafenib Tosylate (CAS: 475207-59-1) rudzi rutsva rwe-multi-target antitumor drug, yakagadziridzwa neGerman Bayer Pharmaceuticals, uye yakaratidza kuwedzera antitumor chiitiko mu preclinical mhuka bvunzo.Sorafenib inowanikwa mumapiritsi e200-mg ekutonga nemuromo uye inoshandiswa mukurapa kweRCC neHCC.Sorafenib Tosylate (CAS: 475207-59-1) inogona panguva imwechete kukanganisa masero emamota uye tumarara yeropa.Iyo ine kaviri antitumor mhedzisiro: inogona kuvharira sero chiratidzo chekufambisa nzira dzakafambiswa neRAF/MEK/ERK kuvharisa zvakananga tumor cell kukura, uku ichivharisa VEGF uye platelet inotorwa kukura zvinhu (PDGF) receptors kudzivirira kuumbwa kwebundu ropa idzva. midziyo, nokudaro zvisina kunanga inhibiting bundu sero kukura.Sorafenib inhibitor yeRaf-1 uye B-RAF pamwe chete neanoverengeka tyrosine kinases.
