Tacrolimus FK-506 Fujimycin CAS 104987-11-3 API Factory High Purity

Tsanangudzo Pfupi

Zita reKemikari: Tacrolimus

Synonyms: FK-506;Fujimycin

CAS: 104987-11-3

Chitarisiko: Ichena-Ichena kana Yero Yero Yakanaka Powder, isinganhuhwi, Yakakosha Inonaka Inonaka

Assay: ≥72.0% (HPLC, pane yakaomeswa nheyo)

API, High Quality, Commercial Production

E-mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Tsanangudzo:

Mugadziri ane Kuchena Kwepamusoro uye Hwakagadzikana Hunhu
Zita reKemikari: Tacrolimus
Synonyms: FK-506;Fujimycin
CAS: 104987-11-3
API, High Quality, Commercial Production

Chemical Properties:

Chemical Name	Tacrolimus
Mashoko anoreva zvakafanana	FK-506;Fujimycin
Nhamba yeCAS	104987-11-3
Nhamba yeCAT	RF-API46
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Matani
Molecular Formula	C44H69NO12
Molecular Weight	804.02
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Off-White kana Yellow Fine Poda, isinganhuhwi, Special Sweet Taste
Identification	Inofanira kuva Positive Reaction
Kujeka	Teerera neChimiro
pH	5.0~6.0
Chloride	≤0.014%
Sulfate	≤0.029%
Masimbi anorema (Pb)	≤10ppm
Arsenic	≤0.0002%
Kunyorova (KF)	≤8.0%
Residue paIgnition	18.0%~22.0%
Assay	≥72.0% (HPLC, pane yakaomeswa nheyo)
Test Standard	Enterprise Standard
Usage	API

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.

Zvakanakira:

FAQ:

Application:

Tacrolimus (zvakare FK-506 kana Fujimycin) is immunosuppressive drug iro rinonyanya kushandiswa kuri mushure mekudyarwa kwenhengo kuderedza chiitiko chemurwere immune system uye nekudaro njodzi yekurambwa kwenhengo.Inoshandiswawo mukugadzirwa kwemusoro mukurapa kweatopic dermatitis yakaoma, yakanyanya refractory uveitis mushure mekutapurwa kwemwongo, uye ganda mamiriro vitiligo.Tacrolimus yakatanga kutorwa mumuto wekuvirisa weStreptomyces tsukuba, utachiona hwevhu hunowanikwa muTsukuba, Japan.Zita rekuti tacrolimus rinotorwa nekutora 't' yeTsukuba, zita regomo pakatorwa sampu yevhu, 'acrol' ye macrolide uye 'imus' ye immunosuppressant.Kunyangwe zvimiro zvisina hukama ne cyclosporin, tacrolimus inoratidza yakafanana spectrum ye immunosuppressive mhedzisiro kune uyu mumiririri pamasero uye mamorekuru level.Zvidzidzo zvekutanga zvakaratidza kuti tacrolimus yaive yakasimba immunosuppressant, ichiratidza kanenge ka100-yakakura in vitro potency pane cyclosporin inhibiting T cell activation.Zvidzidzo zvinotevera mu vivo zvakaratidza tacrolimus kuti ishande mukudzvanya zvinongoerekana zvaitika uye kuyedza autoimmune chirwere, uye mukudzivirira alllograft uye kurambwa kwexenograft mumhando dzemhuka dzekuisirwa nhengo.Pakutanga, tacrolimus yaishandiswa kuita systemic immunosuppression yevarwere vakange vaitwa allograft transplants kuti vadzivise kuramba magrafts avo matsva.Nenguva isipi, zvisinei, kuburikidza nerubatsiro rweserendipity yesainzi, zvakaonekwa kuti tacrolimus inogona kuunza mhedzisiro yakanaka mukukanganiswa kweganda mune vamwe varwere vaive vaiswa transplantation.Kuwanikwa kwetacrolimus nekudaro kwakatungamira mukunzwisisa kwakanyanya kweganda pathology, semuenzaniso weatopic dermatitis.Mushure mezvo, kumwe kushandiswa kwepamusoro kwetacrolimus kwakashumwa uye kushandiswa kwemumiririri uyu mudermatology kuri kuwedzera zvishoma nezvishoma.