Temozolomide (TMZ) CAS 85622-93-1 Assay 99.0% ~ 101.0% API Factory High Purity
Supply Temozolomide uye Related Intermediates:
Temozolomide CAS: 85622-93-1
4(5)-Amino-5(4)-Imidazolecarboxamide CAS: 360-97-4
5(4)-Amino-4(5)-Imidazolecarboxamide Hydrochloride CAS: 72-40-2
| Chemical Name | Temozolomide |
| Mashoko anoreva zvakafanana | 3,4-Dihydro-3-Methyl-4-Oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-Carboxamide |
| Nhamba yeCAS | 85622-93-1 |
| Nhamba yeCAT | RF-API29 |
| Stock Status | MuStock, Kugadzirwa Kunokwira Kusvika Matani |
| Molecular Formula | C6H6N6O2 |
| Molecular Weight | 194.15 |
| Melting Point | 212 ℃ dec. |
| Brand | Ruifu Chemical |
| Item | Zvinotsanangurwa |
| Chitarisiko | Ichena kusvika kuChiedza Pink Powder |
| Identification | By IR, HPLC |
| Residual Solvents | Dimethyl Sulphoxide ≤0.50% |
| Related Substances | |
| Kusachena AIC | ≤0.10% |
| Kusachena Kumwechete | ≤0.10% |
| Zorora Zvisina Kuzivikanwa | ≤0.30% |
| Zvose Zvisina Kuchena | ≤0.30% |
| Heavy Metals | ≤10ppm |
| Kurasika paKuomesa | ≤0.50% |
| Residue paIgnition | ≤0.10% |
| Assay | 99.0% ~ 101.0% (HPLC pane yakaomeswa nheyo) |
| Test Standard | Enterprise Standard |
| Usage | Active Pharmaceutical Ingredient (API) |
Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.
Shanghai Ruifu Chemical Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi weTemozolomide (CAS: 85622-93-1) ine mhando yepamusoro.Temozolomide (TMZ) is an oral alkylating agent inoshandiswa kurapa Glioblastoma Multiforme (GBM) uye Astrocytomas, Metastatic Melanoma.
Temozolomide ndiyo yekutanga inoshanda nemuromo-yakatorwa imidazole uye tetrazine-class anticancer drug inova yechizvarwa chechipiri chealkylating agent ine antitumor basa pasina chiropa metabolic activation mushure mekutonga nemuromo.Iyo inoratidzirwa nekupinda nyore nyore kuburikidza neropa-uropi chinovharira, kushivirira kwakanaka uye kusasimudzwa nemimwe mishonga toxicity, uye kuva ne synergistic mhedzisiro neradiotherapy iyo yakakodzera kurapa yakashata glioma kudzoka mushure mekurapa kwakajairika senge glioblastoma multiforme tumors kana degenerative astrocytoma.Mushonga wekutanga wekurapa metastatic melanoma.
Temozolomide yakatanga kugadzirwa neCancer Research UK Group, yozoendeswa kuSchering-Plough Company (United States) kuti igadziriswe.Iyo ine chinyorwa chemakemikari chimiro uye ndeyechina-imidazole inotorwa.Muna 1999, yakatenderwa kupinda mumusika muEU neUS umo chiratidzo chinotenderwa muUnited States chiri kunyanya kurapwa kwemutsara wechipiri glioblastoma multiforme uye degenerative star gliomas uye zviratidzo zvinotenderwa zveEU ndezvekurapa kukura kana kudzorerazve glioblastoma multiforme. iyo yakatove pasi pekurapa kwakajairika.Kushanda kwe temozolomide pakurapa glioblastoma multiforme kwave kucherechedzwa zvakanyanya muEurope.
