Tenofovir Alafenamide Hemifumarate TAF CAS 1392275-56-7 API Factory Anti-HIV High Quality

Tsanangudzo Pfupi

Zita: Tenofovir Alafenamide Hemifumarate (TAF)

CAS: 1392275-56-7

Machena kusvika Anenge Akachena Makristasi kana Crystalline Powder

Chiyero: 98.0% ~ 102.0%

Mushonga weTenofovir, unoshandiswa musanganiswa kurapa hutachiona hweHIV-1

High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

Tumira email kwatiri

Product Detail

Product Tags

Tsanangudzo:

Commerce Supply Tenofovir Related Intermediates:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl Isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl)phosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl)adenine CAS 14047-28-0
Diethyl (Hydroxymethyl)phosphonate CAS 3084-40-0
Adenine CAS 73-24-5

Chemical Properties:

Chemical Name	Tenofovir Alafenamide Hemifumarate
Mashoko anoreva zvakafanana	TAF;GS-7340 Hemifumarate
Nhamba yeCAS	1392275-56-7
Nhamba yeCAT	RF-API91
Stock Status	MuStock, Kugadzirwa Kunokwira Kusvika Mazana emaKilogram
Molecular Formula	C25H33N6O9P
Molecular Weight	592.55
Storage Temperature	Yakavharwa muKuoma, Kwemukamuri Tembiricha
Brand	Ruifu Chemical

Zvinotsanangurwa:

Item	Zvinotsanangurwa
Chitarisiko	Machena kusvika Anenge Akachena Makristasi kana Crystalline Powder
Solubility	Soluble muDimethylformamide, uye Methanol;Zvishoma Soluble mumvura uye THF;Zvishoma Soluble muAcetonitrile uye Insoluble muDichloromethane uye Toluene
Identification A	Iyo IR absorption spectra inofanirwa kuenderana nereferensi
Kuzivikanwa B	Nguva yekuchengeta yenhongonya huru yemhinduro yemuenzaniso mukutsunga kwemukati chromatogram inoenderana neiyo yereferensi mhinduro.
Chiziviso C	Iyo Fumaric Acid yekuchengeta nguva yepamusoro-soro mukutemerwa kwemukati chromatogram inoenderana nepamusoro pereferenzi.
Mvura Yemukati (neKF)	≤1.0%
Kujeka Kwemhinduro	Chaizvoizvo hapana zvidimbu zvinooneka mu2% (w/v) yeMethanol Solution kujekeswa
Residual Solvent
Acetonitrile	≤410ppm
Ethanol	≤5000ppm
Dichloromethane	≤600ppm
Toluene	≤890ppm
Residue paIgnition	≤0.10%
Heavy Metals	≤20ppm
Related Substances
PMPA	≤1.0%
PMPA Anhydride	≤0.75%
Imwe Phenyl PMPA	≤1.0%
Chero Kusachena Kusina Kutaurwa	≤0.15%
Zvose Zvisina Kuchena	≤2.0%
Isomer	≤1.0%
Zviri mukati meFumaric Acid	9.0% ~ 13.0% (pane anhydrous basis)
Microbial Limits
Total Aerobic Microbial Count	≤1000CFU/g
Yeasts uye Molds Count	≤100CFU/g
Escherichia Coli	Absent
Assay	98.0% ~ 102.0% (pane anhydrous uye solvent-isina hwaro)
Test Standard	Enterprise Standard

Package & Kuchengeta:

Package: Bhodhoro, Aluminium foil bag, Cardboard dhiramu, 25kg/Drum, kana zvinoenderana nezvinodiwa nemutengi.

Storage Condition:Chengetedza mumidziyo yakavharwa panzvimbo inotonhorera uye yakaoma;Dzivirira kubva kuchiedza, mwando uye tumbuyu.

Zvakanakira:

FAQ:

Application:

Tenofovir Alafenamide Hemifumarate (TAF, GS-7340 hemifumarate), CAS 1392275-56-7, is nucleotide reverse transcriptase inhibitor (NRTIs) uye novel prodrug yeTenofovir (TFV).Nekuvhara reverse transcriptase, TAF inodzivirira HIV kuti isawanda uye inogona kuderedza huwandu hweHIV mumuviri.Tenofovir alafenamide iprodrug, zvinoreva kuti mushonga usingashandiswe.Mumuviri, tenofovir alafenamide inoshandurwa kuita Tenofovir diphosphate (TFV-DP).Tenofovir Alafenamide Fumarate yakabvumidzwa muna Mbudzi 2015 kurapwa kweHIV-1.